Vesicoureteral Reflux Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A ureteral disease characterized by backward flow of urine from the urinary bladder into the ureter. (Human Disease Ontology, DOID_9620)
External Link https://www.disgenet.org/browser/0/1/0/C1970483
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Genes

44 genes associated with the disease Vesicoureteral Reflux in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AMBP alpha-1-microglobulin/bikunin precursor
ANGPT2 angiopoietin 2
ATM ATM serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CD34 CD34 molecule
COL4A1 collagen, type IV, alpha 1
CRP C-reactive protein, pentraxin-related
CXCL8 chemokine (C-X-C motif) ligand 8
EGF epidermal growth factor
EMP1 epithelial membrane protein 1
EYA1 EYA transcriptional coactivator and phosphatase 1
GFRA1 GDNF family receptor alpha 1
GJA1 gap junction protein, alpha 1, 43kDa
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GREM1 gremlin 1, DAN family BMP antagonist
IL17B interleukin 17B
IL19 interleukin 19
IL20 interleukin 20
KLK1 kallikrein 1
LCN2 lipocalin 2
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
PAX2 paired box 2
PTX3 pentraxin 3, long
REN renin
RET ret proto-oncogene
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLIT2 slit homolog 2 (Drosophila)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOX17 SRY (sex determining region Y)-box 17
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TNXB tenascin XB
UPK1A uroplakin 1A
UPK3A uroplakin 3A
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)