| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/3009355 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Vicriviroc relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DIPK1B | divergent protein kinase domain 1B | 1.42 |
| TRIM29 | tripartite motif containing 29 | 1.07 |
| WDR90 | WD repeat domain 90 | 1.05 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.91 |
| TENM2 | teneurin transmembrane protein 2 | 0.89 |
| DES | desmin | 0.77 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.75 |
| SLC41A3 | solute carrier family 41, member 3 | 0.73 |
| C19ORF54 | chromosome 19 open reading frame 54 | 0.65 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | 0.58 |
| DOCK3 | dedicator of cytokinesis 3 | 0.57 |
| ECI1 | enoyl-CoA delta isomerase 1 | 0.56 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.54 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.52 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.5 |
| ACTBL2 | actin, beta-like 2 | 0.5 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.46 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.46 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | 0.46 |
| SEPTIN4 | septin 4 | 0.46 |
| TOB1 | transducer of ERBB2, 1 | 0.45 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.45 |
| SYTL2 | synaptotagmin-like 2 | 0.43 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.43 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | 0.43 |
| ZBTB39 | zinc finger and BTB domain containing 39 | 0.41 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 0.41 |
| RPL37A | ribosomal protein L37a | 0.41 |
| TRIM62 | tripartite motif containing 62 | 0.4 |
| ZNF597 | zinc finger protein 597 | 0.39 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.38 |
| ANKRD54 | ankyrin repeat domain 54 | 0.36 |
| CCDC9 | coiled-coil domain containing 9 | 0.35 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.35 |
| RILPL2 | Rab interacting lysosomal protein-like 2 | 0.34 |
| TSPAN33 | tetraspanin 33 | 0.34 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.33 |
| PIMREG | PICALM interacting mitotic regulator | 0.33 |
| ZDHHC2 | zinc finger, DHHC-type containing 2 | 0.32 |
| TEP1 | telomerase-associated protein 1 | 0.32 |
| CCDC66 | coiled-coil domain containing 66 | 0.31 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.31 |
| SLC25A39 | solute carrier family 25, member 39 | 0.31 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.3 |
| H2AZ1 | H2A.Z variant histone 1 | 0.3 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | 0.29 |
| SPPL2B | signal peptide peptidase like 2B | 0.29 |
| ZC3H6 | zinc finger CCCH-type containing 6 | 0.29 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.29 |
| ZNF440 | zinc finger protein 440 | 0.29 |
| FUNDC1 | FUN14 domain containing 1 | 0.29 |
| AMACR | alpha-methylacyl-CoA racemase | 0.28 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) | 0.27 |
| AURKAIP1 | aurora kinase A interacting protein 1 | 0.27 |
| IRX4 | iroquois homeobox 4 | 0.27 |
| FAM20C | family with sequence similarity 20, member C | 0.27 |
| SET | SET nuclear proto-oncogene | 0.27 |
| SUFU | suppressor of fused homolog (Drosophila) | 0.27 |
| SPPL3 | signal peptide peptidase like 3 | 0.26 |
| MT-ND5 | NADH dehydrogenase, subunit 5 (complex I) | 0.26 |
| AXIN2 | axin 2 | 0.26 |
| MLF1 | myeloid leukemia factor 1 | 0.26 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.25 |
| NPHP4 | nephronophthisis 4 | 0.25 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.25 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | 0.25 |
| TIGD1 | tigger transposable element derived 1 | 0.25 |
| MAP2 | microtubule-associated protein 2 | 0.25 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.25 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.25 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.24 |
| CDK10 | cyclin-dependent kinase 10 | 0.23 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.23 |
| VMP1 | vacuole membrane protein 1 | 0.23 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | 0.22 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.22 |
| ADI1 | acireductone dioxygenase 1 | 0.22 |
| GEN1 | GEN1 Holliday junction 5' flap endonuclease | 0.22 |
| MTUS2 | microtubule associated tumor suppressor candidate 2 | 0.22 |
| TNNI3K | TNNI3 interacting kinase | 0.22 |
| DMAC2 | distal membrane arm assembly component 2 | 0.22 |
| TBRG1 | transforming growth factor beta regulator 1 | 0.22 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 | 0.22 |
| PACRGL | PARK2 co-regulated-like | 0.21 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.21 |
| WDR73 | WD repeat domain 73 | 0.21 |
| RPS20 | ribosomal protein S20 | 0.21 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.21 |
| TMEM205 | transmembrane protein 205 | 0.21 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.21 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.21 |
| AGFG2 | ArfGAP with FG repeats 2 | 0.21 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.21 |
| BSG | basigin (Ok blood group) | 0.2 |
| ENTR1 | endosome associated trafficking regulator 1 | 0.2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.2 |
| CCDC170 | coiled-coil domain containing 170 | 0.2 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | 0.2 |
| FAM241A | family with sequence similarity 241 member A | 0.2 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | 0.2 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RAB26 | RAB26, member RAS oncogene family | -0.75 |
| GLRX | glutaredoxin (thioltransferase) | -0.74 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -0.7 |
| HFE | hemochromatosis | -0.68 |
| ZNF888 | zinc finger protein 888 | -0.58 |
| PLAUR | plasminogen activator, urokinase receptor | -0.58 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.56 |
| TULP4 | tubby like protein 4 | -0.56 |
| C15ORF61 | chromosome 15 open reading frame 61 | -0.56 |
| RBKS | ribokinase | -0.54 |
| DMGDH | dimethylglycine dehydrogenase | -0.53 |
| AKNA | AT-hook transcription factor | -0.5 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.49 |
| PRIMPOL | primase and polymerase (DNA-directed) | -0.47 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.47 |
| FSTL1 | follistatin-like 1 | -0.46 |
| ZNF430 | zinc finger protein 430 | -0.45 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.44 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.44 |
| ADCY6 | adenylate cyclase 6 | -0.44 |
| RMDN2 | regulator of microtubule dynamics 2 | -0.43 |
| PPP1R2B | PPP1R2 family member B | -0.43 |
| ATP13A2 | ATPase type 13A2 | -0.43 |
| UVSSA | UV-stimulated scaffold protein A | -0.4 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.39 |
| GJB3 | gap junction protein, beta 3, 31kDa | -0.38 |
| TMEM179B | transmembrane protein 179B | -0.38 |
| UBAP1 | ubiquitin associated protein 1 | -0.37 |
| JUN | jun proto-oncogene | -0.37 |
| MRAS | muscle RAS oncogene homolog | -0.37 |
| BCL9 | B-cell CLL/lymphoma 9 | -0.36 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.35 |
| CEP57 | centrosomal protein 57kDa | -0.35 |
| ZFP1 | ZFP1 zinc finger protein | -0.35 |
| BTBD11 | BTB (POZ) domain containing 11 | -0.35 |
| MT1L | metallothionein 1L (gene/pseudogene) | -0.34 |
| RINL | Ras and Rab interactor-like | -0.34 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.34 |
| SERAC1 | serine active site containing 1 | -0.34 |
| CBR3 | carbonyl reductase 3 | -0.34 |
| TNXB | tenascin XB | -0.34 |
| ZBTB8A | zinc finger and BTB domain containing 8A | -0.34 |
| GGT7 | gamma-glutamyltransferase 7 | -0.34 |
| TSPAN3 | tetraspanin 3 | -0.33 |
| NAGS | N-acetylglutamate synthase | -0.32 |
| ZNF7 | zinc finger protein 7 | -0.32 |
| NCOR1 | nuclear receptor corepressor 1 | -0.32 |
| ZNF564 | zinc finger protein 564 | -0.32 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -0.32 |
| SH2D5 | SH2 domain containing 5 | -0.32 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.32 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.32 |
| KMT5C | lysine methyltransferase 5C | -0.31 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.31 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.31 |
| CLDN3 | claudin 3 | -0.3 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.3 |
| PLA2G12A | phospholipase A2, group XIIA | -0.3 |
| WWC3 | WWC family member 3 | -0.3 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) | -0.3 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | -0.3 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | -0.29 |
| CCNDBP1 | cyclin D-type binding-protein 1 | -0.29 |
| STK16 | serine/threonine kinase 16 | -0.29 |
| FASTK | Fas-activated serine/threonine kinase | -0.29 |
| LETMD1 | LETM1 domain containing 1 | -0.29 |
| N4BP3 | NEDD4 binding protein 3 | -0.28 |
| ZBTB5 | zinc finger and BTB domain containing 5 | -0.28 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.28 |
| ZFP62 | ZFP62 zinc finger protein | -0.28 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | -0.28 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.27 |
| CST6 | cystatin E/M | -0.27 |
| EGR1 | early growth response 1 | -0.27 |
| IFRD1 | interferon-related developmental regulator 1 | -0.27 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -0.27 |
| KCTD21 | potassium channel tetramerization domain containing 21 | -0.27 |
| XIRP1 | xin actin binding repeat containing 1 | -0.27 |
| SNX10 | sorting nexin 10 | -0.27 |
| CDC42SE2 | CDC42 small effector 2 | -0.27 |
| TPM4 | tropomyosin 4 | -0.27 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.27 |
| PLEC | plectin | -0.27 |
| CCDC110 | coiled-coil domain containing 110 | -0.27 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | -0.27 |
| CCDC9B | coiled-coil domain containing 9B | -0.26 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.26 |
| ZNF250 | zinc finger protein 250 | -0.26 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | -0.26 |
| PCDH1 | protocadherin 1 | -0.26 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | -0.26 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | -0.26 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.26 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | -0.26 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | -0.26 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.26 |
| PTMS | parathymosin | -0.26 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.26 |
| ZNF496 | zinc finger protein 496 | -0.26 |
