| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.161552 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.15978 |
| PLAT | plasminogen activator, tissue | 0.153699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0947152 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0877376 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0869252 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0848354 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0781092 |
| AHNAK | AHNAK nucleoprotein | 0.0778612 |
| DST | dystonin | 0.0746634 |
| SON | SON DNA binding protein | 0.0679845 |
| HDAC9 | histone deacetylase 9 | 0.0663473 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0653844 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0631529 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.062503 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0587179 |
| CANX | calnexin | 0.0586681 |
| PODXL | podocalyxin-like | 0.0567567 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0565587 |
| SEPTIN7 | septin 7 | 0.0540862 |
| SQSTM1 | sequestosome 1 | 0.0517764 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0500857 |
| PRELID2 | PRELI domain containing 2 | 0.0491968 |
| MAP1B | microtubule-associated protein 1B | 0.0474262 |
| ASPH | aspartate beta-hydroxylase | 0.0473534 |
| ANKRD11 | ankyrin repeat domain 11 | 0.044889 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0443646 |
| MT1X | metallothionein 1X | 0.0440621 |
| TLE4 | transducin-like enhancer of split 4 | 0.043422 |
| CD44 | CD44 molecule (Indian blood group) | 0.0431443 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.042362 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0419411 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0417068 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.04142 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0411971 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0407883 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0403126 |
| FLNA | filamin A, alpha | 0.0386291 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0385894 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0379119 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0373383 |
| NEK7 | NIMA-related kinase 7 | 0.0370643 |
| B2M | beta-2-microglobulin | 0.0350538 |
| EFNA5 | ephrin-A5 | 0.034163 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0338415 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0335538 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0332004 |
| POTEF | POTE ankyrin domain family, member F | 0.032916 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.032729 |
| RND3 | Rho family GTPase 3 | 0.0324684 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0321506 |
| OGA | O-GlcNAcase | 0.031923 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0317248 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0313318 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0313159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0306309 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.030601 |
| ERBIN | erbb2 interacting protein | 0.0305371 |
| SET | SET nuclear proto-oncogene | 0.0303979 |
| JMJD1C | jumonji domain containing 1C | 0.0300622 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298925 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0298247 |
| PRSS23 | protease, serine, 23 | 0.0295888 |
| RTN4 | reticulon 4 | 0.0294249 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0293558 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0292212 |
| ENO1 | enolase 1, (alpha) | 0.0289356 |
| CBX3 | chromobox homolog 3 | 0.0287601 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.028268 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0277267 |
| BPTF | bromodomain PHD finger transcription factor | 0.0270582 |
| MSN | moesin | 0.0270341 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0270305 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.026883 |
| CLTC | clathrin, heavy chain (Hc) | 0.026675 |
| RUNX1 | runt-related transcription factor 1 | 0.0262464 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0261579 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0259729 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0257876 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0256937 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0255808 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0252772 |
| SFTPA2 | surfactant protein A2 | 0.025271 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0250225 |
| ANXA1 | annexin A1 | 0.0250196 |
| NAV2 | neuron navigator 2 | 0.0249391 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0249065 |
| VEGFC | vascular endothelial growth factor C | 0.0248524 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0246322 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0246288 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0243477 |
| ACTN4 | actinin, alpha 4 | 0.0242272 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0241565 |
| SERINC1 | serine incorporator 1 | 0.0240266 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0239007 |
| SP100 | SP100 nuclear antigen | 0.02385 |
| UBXN4 | UBX domain protein 4 | 0.0237913 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0237756 |
| INTS6 | integrator complex subunit 6 | 0.023616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.303443 |
| VIM | vimentin | -0.200248 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.124416 |
| PTMA | prothymosin, alpha | -0.0987518 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0938857 |
| LOX | lysyl oxidase | -0.0915075 |
| FBN1 | fibrillin 1 | -0.0732342 |
| COL1A2 | collagen, type I, alpha 2 | -0.0728828 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0705837 |
| AUTS2 | autism susceptibility candidate 2 | -0.0664215 |
| LOXL2 | lysyl oxidase-like 2 | -0.0632944 |
| S100A6 | S100 calcium binding protein A6 | -0.0604385 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0562716 |
| TPM4 | tropomyosin 4 | -0.0561458 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0561043 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0517671 |
| GPC6 | glypican 6 | -0.0449605 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0428745 |
| HLA-E | major histocompatibility complex, class I, E | -0.042312 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0417975 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414266 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0407508 |
| THBS2 | thrombospondin 2 | -0.0406538 |
| HLA-B | major histocompatibility complex, class I, B | -0.0403763 |
| NDRG1 | N-myc downstream regulated 1 | -0.0399754 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0386065 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0374212 |
| FTL | ferritin, light polypeptide | -0.0354467 |
| CAVIN1 | caveolae associated protein 1 | -0.0354019 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0353182 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0350003 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0344334 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0332273 |
| UBC | ubiquitin C | -0.0324944 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0324837 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.031894 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.030726 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0299511 |
| MEIS2 | Meis homeobox 2 | -0.0297011 |
| TMSB10 | thymosin beta 10 | -0.0294053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0288776 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0288126 |
| INSIG1 | insulin induced gene 1 | -0.0284327 |
| COL5A2 | collagen, type V, alpha 2 | -0.0274268 |
| TPM1 | tropomyosin 1 (alpha) | -0.0272151 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0270635 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0265876 |
| SBF2 | SET binding factor 2 | -0.0251763 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0250025 |
| TNS3 | tensin 3 | -0.0249127 |
| FRMD5 | FERM domain containing 5 | -0.0242451 |
| ANXA2 | annexin A2 | -0.0241614 |
| COL5A1 | collagen, type V, alpha 1 | -0.023611 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0230466 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0228816 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0223477 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0223079 |
| MSI2 | musashi RNA-binding protein 2 | -0.0215676 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0215322 |
| CUX1 | cut-like homeobox 1 | -0.0211972 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0211643 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0208331 |
| TENM3 | teneurin transmembrane protein 3 | -0.0207038 |
| FRMD4A | FERM domain containing 4A | -0.0204514 |
| VEGFA | vascular endothelial growth factor A | -0.0203633 |
| MTSS1 | metastasis suppressor 1 | -0.0203298 |
| TMOD1 | tropomodulin 1 | -0.0202307 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0202209 |
| TAPBP | TAP binding protein (tapasin) | -0.0197402 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.019512 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0195024 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0194492 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0192463 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0192413 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0192306 |
| NPR2 | natriuretic peptide receptor 2 | -0.0188524 |
| TUBB6 | tubulin, beta 6 class V | -0.0188148 |
| GDF15 | growth differentiation factor 15 | -0.0188086 |
| NBAS | neuroblastoma amplified sequence | -0.0188022 |
| IL32 | interleukin 32 | -0.0187737 |
| SERINC3 | serine incorporator 3 | -0.0186851 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0186575 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0185342 |
| COL1A1 | collagen, type I, alpha 1 | -0.0184357 |
| LDHA | lactate dehydrogenase A | -0.0182905 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0182088 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0182002 |
| RAD51B | RAD51 paralog B | -0.0181522 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.01799 |
| RPS13 | ribosomal protein S13 | -0.0179871 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0179438 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0178939 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0178294 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.0178031 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0177492 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0175949 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0175682 |
| FNBP4 | formin binding protein 4 | -0.0175518 |
| RAI14 | retinoic acid induced 14 | -0.0175109 |
| HDLBP | high density lipoprotein binding protein | -0.0174615 |
