| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.116216 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0918408 |
| ANKRD12 | ankyrin repeat domain 12 | 0.083801 |
| JMJD1C | jumonji domain containing 1C | 0.0788215 |
| RPS6 | ribosomal protein S6 | 0.0659093 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0631603 |
| RTN4 | reticulon 4 | 0.0622388 |
| RPS12 | ribosomal protein S12 | 0.0547946 |
| MMP12 | matrix metallopeptidase 12 | 0.0540149 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0532048 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0484522 |
| AREG | amphiregulin | 0.0481885 |
| VMP1 | vacuole membrane protein 1 | 0.046074 |
| MTAP | methylthioadenosine phosphorylase | 0.0437482 |
| YAP1 | Yes-associated protein 1 | 0.0424997 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0409172 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0385996 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0383844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0380165 |
| RPL23 | ribosomal protein L23 | 0.0379595 |
| TPM3 | tropomyosin 3 | 0.0374546 |
| EDARADD | EDAR-associated death domain | 0.0373512 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0339615 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0327306 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0326825 |
| PCM1 | pericentriolar material 1 | 0.0290589 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289979 |
| PDGFC | platelet derived growth factor C | 0.0286056 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0285435 |
| RSF1 | remodeling and spacing factor 1 | 0.0285365 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0284663 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0277764 |
| TMEM41B | transmembrane protein 41B | 0.0273547 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0270742 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0268953 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0268242 |
| YEATS2 | YEATS domain containing 2 | 0.0265745 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0264658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0261907 |
| RPL12 | ribosomal protein L12 | 0.0260375 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0258621 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0258048 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0255327 |
| RUNX1 | runt-related transcription factor 1 | 0.0254037 |
| NHSL1 | NHS-like 1 | 0.0253178 |
| RBM25 | RNA binding motif protein 25 | 0.0248755 |
| IPO7 | importin 7 | 0.0248748 |
| USP34 | ubiquitin specific peptidase 34 | 0.0245526 |
| PNN | pinin, desmosome associated protein | 0.0243002 |
| VCL | vinculin | 0.0242137 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0238165 |
| ADIPOR2 | adiponectin receptor 2 | 0.0237611 |
| RPL37A | ribosomal protein L37a | 0.0230049 |
| CLTC | clathrin, heavy chain (Hc) | 0.0229694 |
| PRELID2 | PRELI domain containing 2 | 0.022841 |
| ERBIN | erbb2 interacting protein | 0.0224612 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0224521 |
| TENM3 | teneurin transmembrane protein 3 | 0.0220899 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0220761 |
| MED13L | mediator complex subunit 13-like | 0.0218289 |
| YBX3 | Y box binding protein 3 | 0.0216959 |
| RPL35A | ribosomal protein L35a | 0.0215807 |
| RPS8 | ribosomal protein S8 | 0.0212063 |
| TNPO1 | transportin 1 | 0.021128 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0208616 |
| OGA | O-GlcNAcase | 0.0208428 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.020193 |
| BRD4 | bromodomain containing 4 | 0.0201678 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.020042 |
| MKI67 | marker of proliferation Ki-67 | 0.0197601 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 0.0197219 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0195717 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0194393 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0193771 |
| BCHE | butyrylcholinesterase | 0.0192873 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0191432 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0189735 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0189557 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0188861 |
| SETD5 | SET domain containing 5 | 0.0188159 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0188112 |
| NEGR1 | neuronal growth regulator 1 | 0.018693 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0186336 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0185849 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0183557 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0183455 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0182916 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0182884 |
| STAG2 | stromal antigen 2 | 0.0182273 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0181799 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0181688 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0181497 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0177016 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0176148 |
| CANX | calnexin | 0.0173928 |
| RBM39 | RNA binding motif protein 39 | 0.0173772 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0170742 |
| PREPL | prolyl endopeptidase-like | 0.01697 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0169634 |
| DIAPH3 | diaphanous-related formin 3 | 0.016861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.149214 |
| NLGN1 | neuroligin 1 | -0.109417 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0839661 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0614631 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0604675 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0540478 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0509713 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462356 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0454438 |
| LDHA | lactate dehydrogenase A | -0.0423078 |
| SYT1 | synaptotagmin I | -0.0399617 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0396875 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0385617 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0361209 |
| TMSB10 | thymosin beta 10 | -0.0359575 |
| CLDN1 | claudin 1 | -0.034641 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0323279 |
| FTL | ferritin, light polypeptide | -0.0317692 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0315499 |
| GCG | glucagon | -0.0313737 |
| ACTG1 | actin gamma 1 | -0.0309176 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306654 |
| CCND1 | cyclin D1 | -0.0299701 |
| HDLBP | high density lipoprotein binding protein | -0.0295865 |
| PEG10 | paternally expressed 10 | -0.0293 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0287961 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0275246 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0265839 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0263929 |
| ZNF804A | zinc finger protein 804A | -0.026134 |
| GNAS | GNAS complex locus | -0.0255981 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0253267 |
| TGM2 | transglutaminase 2 | -0.0246269 |
| RPS24 | ribosomal protein S24 | -0.0245758 |
| HSPB1 | heat shock 27kDa protein 1 | -0.024288 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0240339 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0239904 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0234475 |
| NPR2 | natriuretic peptide receptor 2 | -0.0228518 |
| PCDH7 | protocadherin 7 | -0.0225728 |
| WDR45B | WD repeat domain 45B | -0.0219526 |
| CCN2 | cellular communication network factor 2 | -0.0217744 |
| YBX1 | Y box binding protein 1 | -0.0215698 |
| RPL39 | ribosomal protein L39 | -0.0214868 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.0214385 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0214257 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0211952 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0211642 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0209038 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0208866 |
| MATR3 | matrin 3 | -0.0207879 |
| RPL27A | ribosomal protein L27a | -0.0206474 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0204686 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0203485 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0203464 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0203317 |
| AHNAK | AHNAK nucleoprotein | -0.0202562 |
| ANXA1 | annexin A1 | -0.0200344 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0198648 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0198645 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0197775 |
| RPS4X | ribosomal protein S4, X-linked | -0.0197612 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.019647 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0195665 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0195569 |
| ATP11A | ATPase, class VI, type 11A | -0.0194844 |
| ARF1 | ADP-ribosylation factor 1 | -0.0193989 |
| SMYD3 | SET and MYND domain containing 3 | -0.0193772 |
| H1-0 | H1.0 linker histone | -0.0193583 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0193443 |
| RPL4 | ribosomal protein L4 | -0.0193435 |
| KIF5B | kinesin family member 5B | -0.0193059 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0192815 |
| LMO7 | LIM domain 7 | -0.0192456 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0190768 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0189513 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0186424 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.018525 |
| UBB | ubiquitin B | -0.0183834 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0181031 |
| AXIN2 | axin 2 | -0.0179678 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0178366 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0177482 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0175039 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0174788 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0173887 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0171969 |
| FMNL2 | formin-like 2 | -0.0171712 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0171406 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0170644 |
| HMGB2 | high mobility group box 2 | -0.0170614 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0166162 |
| TAPBP | TAP binding protein (tapasin) | -0.0164431 |
| TUBA1C | tubulin, alpha 1c | -0.0163209 |
| DKC1 | dyskeratosis congenita 1, dyskerin | -0.0163101 |
| TMEM108 | transmembrane protein 108 | -0.0162431 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0160452 |
| MGAT4C | MGAT4 family, member C | -0.0160328 |
| EDN1 | endothelin 1 | -0.016014 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0159655 |
