| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.12503 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.103038 |
| B2M | beta-2-microglobulin | 0.102248 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.102243 |
| LCN2 | lipocalin 2 | 0.0837735 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0823969 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0751818 |
| ERBIN | erbb2 interacting protein | 0.0716528 |
| MYO1E | myosin IE | 0.0713463 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.062472 |
| TMC5 | transmembrane channel-like 5 | 0.0623963 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0549411 |
| TXNIP | thioredoxin interacting protein | 0.0514951 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0504242 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0488064 |
| EFNB2 | ephrin-B2 | 0.0486174 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0481618 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0459515 |
| ITGA6 | integrin, alpha 6 | 0.045524 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0448315 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0442391 |
| ZNF292 | zinc finger protein 292 | 0.0434268 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0425492 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0412316 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0408755 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.04067 |
| ENO1 | enolase 1, (alpha) | 0.0399128 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0396704 |
| TRIM2 | tripartite motif containing 2 | 0.0393979 |
| RPS6 | ribosomal protein S6 | 0.0392595 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.038816 |
| SMAD3 | SMAD family member 3 | 0.0382657 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0378932 |
| UBC | ubiquitin C | 0.0357716 |
| MAP7 | microtubule-associated protein 7 | 0.0356645 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0349252 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0342909 |
| MED13 | mediator complex subunit 13 | 0.0340264 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.033718 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332717 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0329267 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0325587 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0325127 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0319211 |
| RUNX1 | runt-related transcription factor 1 | 0.0318317 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0312745 |
| LIMA1 | LIM domain and actin binding 1 | 0.0312524 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0308011 |
| AREG | amphiregulin | 0.0305671 |
| ETV6 | ets variant 6 | 0.0301688 |
| SON | SON DNA binding protein | 0.0300699 |
| BCL2L1 | BCL2-like 1 | 0.0297489 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0296019 |
| RBM47 | RNA binding motif protein 47 | 0.0295854 |
| TJP1 | tight junction protein 1 | 0.029264 |
| IFNGR1 | interferon gamma receptor 1 | 0.0292371 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0286869 |
| PDZD8 | PDZ domain containing 8 | 0.0286839 |
| PKM | pyruvate kinase, muscle | 0.0285284 |
| KLF6 | Kruppel-like factor 6 | 0.0283014 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0280704 |
| FMN1 | formin 1 | 0.0279402 |
| YAP1 | Yes-associated protein 1 | 0.0279358 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0275564 |
| STK24 | serine/threonine kinase 24 | 0.0271352 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0269824 |
| PRSS3 | protease, serine, 3 | 0.0268998 |
| EHF | ets homologous factor | 0.0268346 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0264589 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0264276 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0263954 |
| ABHD2 | abhydrolase domain containing 2 | 0.0257336 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0254225 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0253556 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0253288 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0250765 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0250251 |
| KYNU | kynureninase | 0.0249341 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.024738 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0245076 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0237775 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0234682 |
| RPS8 | ribosomal protein S8 | 0.0227613 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0226669 |
| DIAPH1 | diaphanous-related formin 1 | 0.022416 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0223616 |
| JAK1 | Janus kinase 1 | 0.0223341 |
| MCU | mitochondrial calcium uniporter | 0.0223151 |
| SPATA13 | spermatogenesis associated 13 | 0.0221531 |
| MEIS2 | Meis homeobox 2 | 0.0219731 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0218702 |
| IL20RA | interleukin 20 receptor, alpha | 0.0217296 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.021696 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0216621 |
| GPX2 | glutathione peroxidase 2 | 0.0216446 |
| HKDC1 | hexokinase domain containing 1 | 0.0215732 |
| RNF149 | ring finger protein 149 | 0.0214101 |
| AHI1 | Abelson helper integration site 1 | 0.0213567 |
| IRS2 | insulin receptor substrate 2 | 0.0213091 |
| RPL18 | ribosomal protein L18 | 0.0208486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0907078 |
| LYZ | lysozyme | -0.0650733 |
| SP100 | SP100 nuclear antigen | -0.053928 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0526962 |
| INTS6 | integrator complex subunit 6 | -0.0514508 |
| RNF213 | ring finger protein 213 | -0.0504112 |
| MUC20 | mucin 20, cell surface associated | -0.0491125 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0470445 |
| RIGI | RNA sensor RIG-I | -0.0448235 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0405677 |
| NPSR1 | neuropeptide S receptor 1 | -0.0381033 |
| PLSCR2 | phospholipid scramblase 2 | -0.0376769 |
| XAF1 | XIAP associated factor 1 | -0.0352938 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0327182 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0322436 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0308791 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0288482 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0269545 |
| EGR1 | early growth response 1 | -0.0269043 |
| RAD51B | RAD51 paralog B | -0.0254683 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0249758 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248371 |
| HLA-E | major histocompatibility complex, class I, E | -0.0245131 |
| RPS24 | ribosomal protein S24 | -0.0233921 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0227965 |
| CANX | calnexin | -0.0222742 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0222427 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0221873 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0221559 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0221103 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0216238 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0210832 |
| RPL31 | ribosomal protein L31 | -0.0199616 |
| MMP7 | matrix metallopeptidase 7 | -0.0197742 |
| POU2F2 | POU class 2 homeobox 2 | -0.0194211 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0193918 |
| HM13 | histocompatibility (minor) 13 | -0.0185218 |
| VIM | vimentin | -0.0176834 |
| MX1 | MX dynamin-like GTPase 1 | -0.0175775 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0173192 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0172669 |
| TNS4 | tensin 4 | -0.0164806 |
| HMGB1 | high mobility group box 1 | -0.0163582 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0162932 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0161459 |
| KPNB1 | karyopherin (importin) beta 1 | -0.015911 |
| NDRG1 | N-myc downstream regulated 1 | -0.015336 |
| PMP22 | peripheral myelin protein 22 | -0.0151618 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0150952 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0150003 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0149228 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0147514 |
| FUS | FUS RNA binding protein | -0.014409 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0142786 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.014244 |
| FOSL1 | FOS-like antigen 1 | -0.0141399 |
| S100A6 | S100 calcium binding protein A6 | -0.014082 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0140224 |
| R3HDM2 | R3H domain containing 2 | -0.0139488 |
| DENND1A | DENN/MADD domain containing 1A | -0.0138645 |
| ACTG1 | actin gamma 1 | -0.0138375 |
| CUX1 | cut-like homeobox 1 | -0.0138083 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0136868 |
| IER3 | immediate early response 3 | -0.0135548 |
| FRMD5 | FERM domain containing 5 | -0.0134229 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0133685 |
| SELENOS | selenoprotein S | -0.0133258 |
| CCDC32 | coiled-coil domain containing 32 | -0.0132687 |
| LRRC23 | leucine rich repeat containing 23 | -0.0132627 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0130677 |
| AGR2 | anterior gradient 2 | -0.0129135 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0128775 |
| IGF2 | insulin-like growth factor 2 | -0.0123886 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0122038 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0121683 |
| APOL6 | apolipoprotein L, 6 | -0.0121465 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0119991 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.0119334 |
| HDLBP | high density lipoprotein binding protein | -0.0118886 |
| BRI3BP | BRI3 binding protein | -0.0118715 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0117244 |
| RPLP1 | ribosomal protein, large, P1 | -0.0115501 |
| TPM4 | tropomyosin 4 | -0.0115444 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0115087 |
| RPL38 | ribosomal protein L38 | -0.0114688 |
| RPL7A | ribosomal protein L7a | -0.0114269 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0114219 |
| TRIM25 | tripartite motif containing 25 | -0.0114122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0113019 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0112928 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0112146 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0112102 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0111469 |
| USP18 | ubiquitin specific peptidase 18 | -0.0111068 |
| MYO1D | myosin ID | -0.0110091 |
| TUFT1 | tuftelin 1 | -0.0109027 |
| FBXO39 | F-box protein 39 | -0.0108764 |
| TRIM56 | tripartite motif containing 56 | -0.0108355 |
| RPL5 | ribosomal protein L5 | -0.0108112 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0108033 |