| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.161722 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.133395 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.123351 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.107145 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0925945 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0923157 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0905376 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0805936 |
| HMGA2 | high mobility group AT-hook 2 | 0.0784101 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0731875 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.071481 |
| STC1 | stanniocalcin 1 | 0.0677289 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0676062 |
| FN1 | fibronectin 1 | 0.066118 |
| RND3 | Rho family GTPase 3 | 0.0645677 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0622919 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0604199 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0569933 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0559685 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.055329 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.055099 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0530897 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0526847 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0524061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0518769 |
| IL6ST | interleukin 6 signal transducer | 0.051333 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0503975 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0499516 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0497777 |
| RPS6 | ribosomal protein S6 | 0.0488238 |
| RPS12 | ribosomal protein S12 | 0.0472875 |
| SQSTM1 | sequestosome 1 | 0.0468222 |
| ENO1 | enolase 1, (alpha) | 0.0464637 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0464427 |
| NAV1 | neuron navigator 1 | 0.0456588 |
| SON | SON DNA binding protein | 0.0454117 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0427445 |
| RPS2 | ribosomal protein S2 | 0.0426493 |
| INHBA | inhibin, beta A | 0.041947 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0411958 |
| COL6A3 | collagen, type VI, alpha 3 | 0.039785 |
| POSTN | periostin, osteoblast specific factor | 0.0389867 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0384052 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0358603 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0358467 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0357347 |
| CLTC | clathrin, heavy chain (Hc) | 0.0356037 |
| GOLGB1 | golgin B1 | 0.0355794 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0352436 |
| HDAC9 | histone deacetylase 9 | 0.034672 |
| RPS3 | ribosomal protein S3 | 0.0341836 |
| AGO3 | argonaute RISC catalytic component 3 | 0.033656 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0328846 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0325215 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319236 |
| VMP1 | vacuole membrane protein 1 | 0.031903 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0314546 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0313695 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0310091 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0308517 |
| PGM3 | phosphoglucomutase 3 | 0.0305455 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0305174 |
| ATF4 | activating transcription factor 4 | 0.0303811 |
| SFTPA2 | surfactant protein A2 | 0.0303599 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0300535 |
| COL3A1 | collagen, type III, alpha 1 | 0.0298938 |
| TMF1 | TATA element modulatory factor 1 | 0.0294013 |
| ERBIN | erbb2 interacting protein | 0.0293546 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0289463 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285983 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0284842 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.028402 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0281084 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0280776 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.028002 |
| NAV2 | neuron navigator 2 | 0.027974 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0275805 |
| EP300 | E1A binding protein p300 | 0.0270737 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.026801 |
| RACK1 | receptor for activated C kinase 1 | 0.0263205 |
| MRTFA | myocardin related transcription factor A | 0.0261183 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0260422 |
| RPL37A | ribosomal protein L37a | 0.0259409 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0258304 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0256177 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0255866 |
| RPL18 | ribosomal protein L18 | 0.0254485 |
| SDC2 | syndecan 2 | 0.0253506 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0253426 |
| JAK1 | Janus kinase 1 | 0.0253149 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0252829 |
| BRD4 | bromodomain containing 4 | 0.0252301 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0252144 |
| CDK13 | cyclin-dependent kinase 13 | 0.0251325 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0250249 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0249836 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.024972 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0246957 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0246824 |
| INTS6 | integrator complex subunit 6 | 0.0244847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.174614 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.160957 |
| TPM4 | tropomyosin 4 | -0.160837 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158281 |
| COL1A1 | collagen, type I, alpha 1 | -0.124935 |
| PTMA | prothymosin, alpha | -0.099897 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.09884 |
| IER3 | immediate early response 3 | -0.0969877 |
| FTL | ferritin, light polypeptide | -0.0684772 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0678314 |
| CDH13 | cadherin 13 | -0.0670946 |
| CAVIN1 | caveolae associated protein 1 | -0.0668519 |
| COL1A2 | collagen, type I, alpha 2 | -0.0596286 |
| TMSB10 | thymosin beta 10 | -0.0542841 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0523919 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0523452 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0517147 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0492075 |
| CD44 | CD44 molecule (Indian blood group) | -0.0445791 |
| RRBP1 | ribosome binding protein 1 | -0.0443745 |
| TMSB4X | thymosin beta 4, X-linked | -0.042109 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0420315 |
| LOXL2 | lysyl oxidase-like 2 | -0.040964 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0407112 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0390714 |
| RPLP1 | ribosomal protein, large, P1 | -0.0384168 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0379827 |
| MAP1B | microtubule-associated protein 1B | -0.0365848 |
| ANXA2 | annexin A2 | -0.0360408 |
| LOX | lysyl oxidase | -0.0359794 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0357716 |
| SBF2 | SET binding factor 2 | -0.0355172 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0351078 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0347733 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0323786 |
| YBX1 | Y box binding protein 1 | -0.0319763 |
| SMAD3 | SMAD family member 3 | -0.0317731 |
| CALR | calreticulin | -0.0316849 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0313772 |
| RLF | rearranged L-myc fusion | -0.030865 |
| LDHA | lactate dehydrogenase A | -0.0305028 |
| PXDN | peroxidasin | -0.0302458 |
| USP3 | ubiquitin specific peptidase 3 | -0.0301955 |
| S100A6 | S100 calcium binding protein A6 | -0.0301806 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0296776 |
| PKM | pyruvate kinase, muscle | -0.0292801 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0274013 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0272456 |
| MT2A | metallothionein 2A | -0.0268207 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.026408 |
| COL5A1 | collagen, type V, alpha 1 | -0.0262567 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258139 |
| RAD51B | RAD51 paralog B | -0.025728 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0248159 |
| SERINC3 | serine incorporator 3 | -0.0243335 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0242928 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239379 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0239263 |
| CADM1 | cell adhesion molecule 1 | -0.0238796 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0237353 |
| WDR45B | WD repeat domain 45B | -0.0235229 |
| FOSL1 | FOS-like antigen 1 | -0.0234013 |
| AXL | AXL receptor tyrosine kinase | -0.0229921 |
| RPLP0 | ribosomal protein, large, P0 | -0.0227138 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0226854 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0226817 |
| BNC2 | basonuclin 2 | -0.0226529 |
| RPL38 | ribosomal protein L38 | -0.0225853 |
| HDLBP | high density lipoprotein binding protein | -0.0222818 |
| PRELID2 | PRELI domain containing 2 | -0.0221733 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0221341 |
| HAS2 | hyaluronan synthase 2 | -0.021951 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.021912 |
| CALD1 | caldesmon 1 | -0.0217467 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0216781 |
| RPS24 | ribosomal protein S24 | -0.021618 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0215856 |
| HLA-E | major histocompatibility complex, class I, E | -0.021195 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.021037 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0209804 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0209191 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0206059 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0206023 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0203574 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0202743 |
| RPL19 | ribosomal protein L19 | -0.0202311 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0202037 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0199909 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0199791 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0199688 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199213 |
| ZNF292 | zinc finger protein 292 | -0.019866 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0197065 |
| SEPTIN7 | septin 7 | -0.0196576 |
| TPM1 | tropomyosin 1 (alpha) | -0.0195033 |
| SYNJ2 | synaptojanin 2 | -0.0194893 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0194524 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0193945 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0193881 |
| CCDC91 | coiled-coil domain containing 91 | -0.0192211 |
