| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.216261 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.128888 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.128363 |
| MT2A | metallothionein 2A | 0.113407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0987683 |
| SVIL | supervillin | 0.0903107 |
| FOXP1 | forkhead box P1 | 0.0879414 |
| APOB | apolipoprotein B | 0.0842979 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0752114 |
| DSPP | dentin sialophosphoprotein | 0.0713421 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0705558 |
| RPS6 | ribosomal protein S6 | 0.0626021 |
| RPS12 | ribosomal protein S12 | 0.053414 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0501825 |
| BCL2L1 | BCL2-like 1 | 0.0459722 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.044746 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0428425 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0422004 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0419706 |
| RPL23 | ribosomal protein L23 | 0.0406339 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0397829 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0379372 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0373533 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.035557 |
| AHR | aryl hydrocarbon receptor | 0.0351951 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0339169 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0328653 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.032334 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0320611 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320126 |
| SMAD3 | SMAD family member 3 | 0.0307735 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0303282 |
| INTS6 | integrator complex subunit 6 | 0.0300724 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0295701 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0293677 |
| ATXN1 | ataxin 1 | 0.0289227 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0285578 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0277533 |
| ITGA6 | integrin, alpha 6 | 0.0277429 |
| TF | transferrin | 0.0274885 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0270039 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0268111 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0267314 |
| RPL35A | ribosomal protein L35a | 0.0265856 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0265588 |
| MRTFA | myocardin related transcription factor A | 0.0258264 |
| EHBP1 | EH domain binding protein 1 | 0.0257399 |
| JAK1 | Janus kinase 1 | 0.0256945 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0256195 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0255476 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0255309 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0253262 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.0249891 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0247021 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0243554 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0240337 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0238778 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0238243 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0236644 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0231708 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0229998 |
| KLF6 | Kruppel-like factor 6 | 0.0228154 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0227063 |
| MYO1E | myosin IE | 0.0221574 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0219707 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0219583 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0219232 |
| KYNU | kynureninase | 0.0215777 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.021516 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0213766 |
| HNMT | histamine N-methyltransferase | 0.0213723 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213506 |
| TLE4 | transducin-like enhancer of split 4 | 0.0213303 |
| SQSTM1 | sequestosome 1 | 0.0211525 |
| ANKRD11 | ankyrin repeat domain 11 | 0.02101 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0208782 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0207427 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0204223 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0204118 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0200834 |
| FUS | FUS RNA binding protein | 0.0198387 |
| KIF5B | kinesin family member 5B | 0.0197447 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0195304 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0191837 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0191834 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0191747 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0189021 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0187943 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0187684 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.0186445 |
| DUSP16 | dual specificity phosphatase 16 | 0.0186087 |
| RPL37A | ribosomal protein L37a | 0.0184202 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0183848 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0183771 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0180503 |
| SON | SON DNA binding protein | 0.0180256 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0179475 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0178211 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0177772 |
| RPLP2 | ribosomal protein, large, P2 | 0.0177446 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.219598 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.202068 |
| C3 | complement component 3 | -0.176431 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0987861 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0717134 |
| HMGA1 | high mobility group AT-hook 1 | -0.067822 |
| AHSG | alpha-2-HS-glycoprotein | -0.066501 |
| APOA2 | apolipoprotein A-II | -0.0651672 |
| TMSB10 | thymosin beta 10 | -0.0544936 |
| GPC6 | glypican 6 | -0.0536096 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0523795 |
| NDRG1 | N-myc downstream regulated 1 | -0.052306 |
| PLIN2 | perilipin 2 | -0.0521707 |
| MSI2 | musashi RNA-binding protein 2 | -0.0468822 |
| FTL | ferritin, light polypeptide | -0.0462513 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0451615 |
| VEGFA | vascular endothelial growth factor A | -0.0414352 |
| FN1 | fibronectin 1 | -0.0410325 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0408548 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0406292 |
| LDHA | lactate dehydrogenase A | -0.0400226 |
| PERP | PERP, TP53 apoptosis effector | -0.0397779 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0388118 |
| LYZ | lysozyme | -0.0378511 |
| PKM | pyruvate kinase, muscle | -0.036825 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0366945 |
| TPM4 | tropomyosin 4 | -0.0365707 |
| TMEM123 | transmembrane protein 123 | -0.0362108 |
| EGR1 | early growth response 1 | -0.0356276 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0338374 |
| WDR45B | WD repeat domain 45B | -0.0338231 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0334278 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329893 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0323858 |
| CPE | carboxypeptidase E | -0.0316321 |
| UBC | ubiquitin C | -0.0316209 |
| SDC4 | syndecan 4 | -0.0311446 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0304106 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0300129 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0298048 |
| POTEF | POTE ankyrin domain family, member F | -0.0291431 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0288575 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0286812 |
| GDF15 | growth differentiation factor 15 | -0.0278843 |
| QKI | QKI, KH domain containing, RNA binding | -0.0276473 |
| GSE1 | Gse1 coiled-coil protein | -0.0276256 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0270781 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0268914 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.0267339 |
| GNAS | GNAS complex locus | -0.0265469 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0262152 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0259682 |
| NGLY1 | N-glycanase 1 | -0.0255934 |
| INSIG2 | insulin induced gene 2 | -0.0255026 |
| YBX1 | Y box binding protein 1 | -0.0252823 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0246447 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0245914 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0244314 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0237276 |
| HLA-A | major histocompatibility complex, class I, A | -0.023209 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0228182 |
| PEG3 | paternally expressed 3 | -0.0227021 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.022656 |
| RPLP0 | ribosomal protein, large, P0 | -0.0223 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0218433 |
| RPS24 | ribosomal protein S24 | -0.0212433 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211513 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0210769 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0210387 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0209189 |
| RPS14 | ribosomal protein S14 | -0.020825 |
| GOLGA4 | golgin A4 | -0.0205788 |
| SERINC3 | serine incorporator 3 | -0.0204054 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0200133 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0197094 |
| ACTN1 | actinin, alpha 1 | -0.0196935 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0196783 |
| GLG1 | golgi glycoprotein 1 | -0.0196696 |
| SBF2 | SET binding factor 2 | -0.0193216 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0191407 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0190137 |
| ZNF207 | zinc finger protein 207 | -0.0189524 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0188487 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0187627 |
| GSPT1 | G1 to S phase transition 1 | -0.0186784 |
| TPD52 | tumor protein D52 | -0.0185806 |
| CHKA | choline kinase alpha | -0.018254 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0181738 |
| PFN1 | profilin 1 | -0.0181568 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0179746 |
| ADM | adrenomedullin | -0.0179415 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.017929 |
| NBAS | neuroblastoma amplified sequence | -0.0179058 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.017824 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0177699 |
| PCBP2 | poly(rC) binding protein 2 | -0.0177504 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0175357 |
| DTNA | dystrobrevin, alpha | -0.0175022 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0174368 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0174048 |
