| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.181897 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.16881 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.111831 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0695319 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0658132 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.063962 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0635851 |
| STC1 | stanniocalcin 1 | 0.0626689 |
| INTS6 | integrator complex subunit 6 | 0.0601552 |
| MTSS1 | metastasis suppressor 1 | 0.0598984 |
| CALB1 | calbindin 1, 28kDa | 0.0590977 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0547009 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0536221 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.053099 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0527929 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0527545 |
| B2M | beta-2-microglobulin | 0.0507792 |
| PALLD | palladin, cytoskeletal associated protein | 0.0505104 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0497467 |
| RAI14 | retinoic acid induced 14 | 0.048047 |
| SULF2 | sulfatase 2 | 0.0473156 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0466894 |
| HMGA2 | high mobility group AT-hook 2 | 0.0452556 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0449074 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0446576 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0418173 |
| RPS8 | ribosomal protein S8 | 0.0407969 |
| TXNIP | thioredoxin interacting protein | 0.0395395 |
| RPS6 | ribosomal protein S6 | 0.0384298 |
| LAMC2 | laminin, gamma 2 | 0.0379433 |
| DST | dystonin | 0.0379083 |
| AHNAK | AHNAK nucleoprotein | 0.037822 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0373756 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0363791 |
| SQSTM1 | sequestosome 1 | 0.0344716 |
| PLS3 | plastin 3 | 0.0341343 |
| MTAP | methylthioadenosine phosphorylase | 0.0338025 |
| MT2A | metallothionein 2A | 0.0337674 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0324639 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0323533 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0322795 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0322695 |
| RIGI | RNA sensor RIG-I | 0.0321146 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0320499 |
| RNF217 | ring finger protein 217 | 0.0319121 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0316272 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0308949 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0307228 |
| ITGB8 | integrin, beta 8 | 0.0306412 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0304691 |
| GRAMD1B | GRAM domain containing 1B | 0.0301734 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0286892 |
| RPL11 | ribosomal protein L11 | 0.0284285 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0274975 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0271275 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0270225 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0269999 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0266201 |
| DGKH | diacylglycerol kinase, eta | 0.0265841 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0265603 |
| SP100 | SP100 nuclear antigen | 0.0258593 |
| SVIL | supervillin | 0.0256421 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0246438 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0245344 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0243895 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0242125 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0241815 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0241392 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241269 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0241027 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0240433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0237898 |
| FAM107B | family with sequence similarity 107, member B | 0.0237684 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0235938 |
| AOPEP | aminopeptidase O (putative) | 0.0234743 |
| CUX1 | cut-like homeobox 1 | 0.023078 |
| SIK3 | SIK family kinase 3 | 0.0228622 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0228344 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0227522 |
| AMOTL1 | angiomotin like 1 | 0.0225285 |
| FBXO11 | F-box protein 11 | 0.0220265 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0217194 |
| RPL37A | ribosomal protein L37a | 0.0215394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0215183 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0211913 |
| MYOF | myoferlin | 0.0211869 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.02103 |
| MKI67 | marker of proliferation Ki-67 | 0.0209429 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0209399 |
| RPLP1 | ribosomal protein, large, P1 | 0.0206693 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0206446 |
| CSTB | cystatin B (stefin B) | 0.020558 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0204062 |
| JMJD1C | jumonji domain containing 1C | 0.0203737 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.020245 |
| KIAA1671 | KIAA1671 | 0.0201454 |
| REEP3 | receptor accessory protein 3 | 0.0200938 |
| OXSR1 | oxidative stress responsive 1 | 0.0200928 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0200768 |
| MXRA5 | matrix-remodelling associated 5 | 0.0200624 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.162785 |
| NDRG1 | N-myc downstream regulated 1 | -0.122997 |
| SULF1 | sulfatase 1 | -0.0891401 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0676123 |
| MEF2A | myocyte enhancer factor 2A | -0.0592164 |
| NRG1 | neuregulin 1 | -0.0585015 |
| BCL2L1 | BCL2-like 1 | -0.0564866 |
| POTEF | POTE ankyrin domain family, member F | -0.0541035 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0505612 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0499847 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0497708 |
| EPHA2 | EPH receptor A2 | -0.0484794 |
| RIN2 | Ras and Rab interactor 2 | -0.048443 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0468768 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0456405 |
| TMSB10 | thymosin beta 10 | -0.0452453 |
| RBM39 | RNA binding motif protein 39 | -0.0452371 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0450466 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0433861 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0426049 |
| EMP1 | epithelial membrane protein 1 | -0.0410184 |
| METTL15 | methyltransferase like 15 | -0.0409402 |
| GOLGA4 | golgin A4 | -0.0408754 |
| TGM2 | transglutaminase 2 | -0.0399813 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0397067 |
| KIAA1217 | KIAA1217 | -0.0395506 |
| MSN | moesin | -0.039285 |
| PKM | pyruvate kinase, muscle | -0.0388929 |
| CLU | clusterin | -0.0382895 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0382407 |
| PLEC | plectin | -0.0380045 |
| FOSL1 | FOS-like antigen 1 | -0.0378345 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0368384 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0367294 |
| PDLIM1 | PDZ and LIM domain 1 | -0.0364306 |
| DSTN | destrin (actin depolymerizing factor) | -0.0363674 |
| MYO10 | myosin X | -0.0360857 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0360541 |
| SBF2 | SET binding factor 2 | -0.0349931 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.034791 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -0.0345323 |
| PRELID2 | PRELI domain containing 2 | -0.0338731 |
| LAMA5 | laminin, alpha 5 | -0.0334745 |
| FLNA | filamin A, alpha | -0.0332195 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0331493 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0328241 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0327152 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.032072 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0318303 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0316477 |
| EGR1 | early growth response 1 | -0.0315793 |
| EZR | ezrin | -0.0313349 |
| ITGA6 | integrin, alpha 6 | -0.0312582 |
| EFHD2 | EF-hand domain family, member D2 | -0.031184 |
| ANXA11 | annexin A11 | -0.030277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0300491 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0295924 |
| ITGB4 | integrin, beta 4 | -0.0292699 |
| PFN1 | profilin 1 | -0.029165 |
| LMNA | lamin A/C | -0.0288692 |
| COG5 | component of oligomeric golgi complex 5 | -0.0287251 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0284649 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02813 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.027533 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0273771 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0268807 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0264621 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0263407 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0261173 |
| SMAD3 | SMAD family member 3 | -0.0261053 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0259947 |
| CD47 | CD47 molecule | -0.0259508 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0255942 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0255259 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0253129 |
| ZNF292 | zinc finger protein 292 | -0.0252936 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0250194 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0245189 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0244817 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0244202 |
| MYADM | myeloid-associated differentiation marker | -0.0238909 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0237966 |
| NPTN | neuroplastin | -0.023676 |
| CCNL1 | cyclin L1 | -0.0235769 |
| CALU | calumenin | -0.0235506 |
| COPA | coatomer protein complex, subunit alpha | -0.0233677 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0232937 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0230057 |
| ANLN | anillin, actin binding protein | -0.0226476 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0226238 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0225974 |
| GATA6 | GATA binding protein 6 | -0.0223121 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.022168 |
| TAPBP | TAP binding protein (tapasin) | -0.0219219 |
| NBAS | neuroblastoma amplified sequence | -0.021888 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0217946 |
| ARF4 | ADP-ribosylation factor 4 | -0.0216606 |
| NF1 | neurofibromin 1 | -0.0216412 |
| WASF2 | WAS protein family, member 2 | -0.0216029 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0212278 |
