| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.156061 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.132374 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11494 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0911581 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0847495 |
| TMC5 | transmembrane channel-like 5 | 0.0772548 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0686616 |
| FTL | ferritin, light polypeptide | 0.0663559 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0606299 |
| EMP1 | epithelial membrane protein 1 | 0.0571342 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.055517 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0524722 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0510063 |
| AGR2 | anterior gradient 2 | 0.0496666 |
| AHNAK | AHNAK nucleoprotein | 0.0483796 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0474285 |
| LMO7 | LIM domain 7 | 0.0474055 |
| RPS6 | ribosomal protein S6 | 0.0471119 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0432057 |
| RPS12 | ribosomal protein S12 | 0.0429822 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0428677 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0427672 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0420083 |
| CANX | calnexin | 0.0417317 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0413143 |
| ANXA1 | annexin A1 | 0.0405035 |
| DSPP | dentin sialophosphoprotein | 0.0397559 |
| ANXA2 | annexin A2 | 0.0392249 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0385675 |
| EPCAM | epithelial cell adhesion molecule | 0.0385208 |
| RPL26 | ribosomal protein L26 | 0.0376518 |
| RPS8 | ribosomal protein S8 | 0.0365433 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0361613 |
| GOLGA4 | golgin A4 | 0.0333125 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0312951 |
| ENO1 | enolase 1, (alpha) | 0.0306692 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0304803 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0303972 |
| RPS2 | ribosomal protein S2 | 0.0302595 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0297259 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0287399 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275548 |
| TXNRD1 | thioredoxin reductase 1 | 0.0271693 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0268399 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0266663 |
| LAMB3 | laminin, beta 3 | 0.0261023 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0260659 |
| SEPTIN9 | septin 9 | 0.0257509 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0253475 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0252723 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0248541 |
| H1-0 | H1.0 linker histone | 0.0247639 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0246502 |
| RPL18 | ribosomal protein L18 | 0.0245651 |
| NDRG1 | N-myc downstream regulated 1 | 0.0245601 |
| AHR | aryl hydrocarbon receptor | 0.0242953 |
| S100P | S100 calcium binding protein P | 0.0242736 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0241377 |
| MKI67 | marker of proliferation Ki-67 | 0.0239721 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0238425 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0235546 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235321 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.0231338 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0230244 |
| SQSTM1 | sequestosome 1 | 0.0229552 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.022836 |
| RPS3 | ribosomal protein S3 | 0.0225104 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0223862 |
| GPX2 | glutathione peroxidase 2 | 0.0221747 |
| SFTPA2 | surfactant protein A2 | 0.0220965 |
| TMEM45B | transmembrane protein 45B | 0.0217327 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0216799 |
| TMF1 | TATA element modulatory factor 1 | 0.0216035 |
| KIF5B | kinesin family member 5B | 0.0212805 |
| HDLBP | high density lipoprotein binding protein | 0.0212772 |
| RPL23 | ribosomal protein L23 | 0.020554 |
| OGA | O-GlcNAcase | 0.0205 |
| HLA-C | major histocompatibility complex, class I, C | 0.0204009 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.020306 |
| MYO6 | myosin VI | 0.0202224 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0201694 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0198493 |
| SERINC1 | serine incorporator 1 | 0.0198428 |
| MTDH | metadherin | 0.0197701 |
| CDK13 | cyclin-dependent kinase 13 | 0.019674 |
| FAM13A | family with sequence similarity 13, member A | 0.0196133 |
| SET | SET nuclear proto-oncogene | 0.0194512 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0192488 |
| UBB | ubiquitin B | 0.0190836 |
| KLF6 | Kruppel-like factor 6 | 0.0188131 |
| MORF4L2 | mortality factor 4 like 2 | 0.018774 |
| SSR1 | signal sequence receptor, alpha | 0.0187527 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0184508 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0184125 |
| MYOF | myoferlin | 0.0184095 |
| GOLGB1 | golgin B1 | 0.0183614 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0183455 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.0181959 |
| PHF3 | PHD finger protein 3 | 0.0179588 |
| CLTC | clathrin, heavy chain (Hc) | 0.0179524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.223647 |
| NPSR1 | neuropeptide S receptor 1 | -0.179166 |
| POTEF | POTE ankyrin domain family, member F | -0.136505 |
| TMSB10 | thymosin beta 10 | -0.126601 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.118787 |
| PTMA | prothymosin, alpha | -0.108966 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0714967 |
| VEGFA | vascular endothelial growth factor A | -0.0595558 |
| RUNX1 | runt-related transcription factor 1 | -0.048868 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0457276 |
| CDK6 | cyclin-dependent kinase 6 | -0.0454541 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0445805 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0437742 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0404994 |
| PFN1 | profilin 1 | -0.0404955 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0397683 |
| CLDN7 | claudin 7 | -0.0397091 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0392125 |
| PCBP2 | poly(rC) binding protein 2 | -0.038687 |
| CCNL1 | cyclin L1 | -0.0382352 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0372569 |
| RNF213 | ring finger protein 213 | -0.0368323 |
| S100A6 | S100 calcium binding protein A6 | -0.0365294 |
| FAT1 | FAT atypical cadherin 1 | -0.0361619 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0353203 |
| COBL | cordon-bleu WH2 repeat protein | -0.0346331 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0343303 |
| ETV6 | ets variant 6 | -0.0336958 |
| S100A11 | S100 calcium binding protein A11 | -0.0330062 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0327444 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0323822 |
| LYZ | lysozyme | -0.0315525 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0314346 |
| PRKCA | protein kinase C, alpha | -0.0308898 |
| ITGB4 | integrin, beta 4 | -0.0304928 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0298742 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0296174 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293392 |
| TTYH3 | tweety family member 3 | -0.0283524 |
| KLK10 | kallikrein-related peptidase 10 | -0.0279107 |
| BCL2L1 | BCL2-like 1 | -0.0277812 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0265918 |
| AUTS2 | autism susceptibility candidate 2 | -0.0265603 |
| EGR1 | early growth response 1 | -0.0265014 |
| KRT18 | keratin 18, type I | -0.0258994 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0258813 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0255686 |
| RAD51B | RAD51 paralog B | -0.0255238 |
| TPM4 | tropomyosin 4 | -0.025325 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.025293 |
| KRT7 | keratin 7, type II | -0.025093 |
| CUX1 | cut-like homeobox 1 | -0.0248807 |
| ABHD2 | abhydrolase domain containing 2 | -0.0248346 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0248223 |
| SULF2 | sulfatase 2 | -0.0247151 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0246227 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0239945 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0237817 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0236029 |
| DIAPH2 | diaphanous-related formin 2 | -0.0233699 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0233618 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0228397 |
| YAP1 | Yes-associated protein 1 | -0.0227233 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0226072 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0222835 |
| TJP1 | tight junction protein 1 | -0.0220934 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0218552 |
| CBX3 | chromobox homolog 3 | -0.0217715 |
| IGSF9B | immunoglobulin superfamily, member 9B | -0.0217537 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0216155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.021499 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0212941 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0209917 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0207402 |
| FMNL2 | formin-like 2 | -0.0206872 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0204546 |
| ANXA11 | annexin A11 | -0.0204269 |
| TAPBP | TAP binding protein (tapasin) | -0.0202538 |
| ATXN1 | ataxin 1 | -0.0200802 |
| CCND1 | cyclin D1 | -0.0200772 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0200713 |
| FASN | fatty acid synthase | -0.0200681 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0199022 |
| PTK2 | protein tyrosine kinase 2 | -0.0198686 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0194062 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0192249 |
| TMEM123 | transmembrane protein 123 | -0.0192105 |
| DIAPH1 | diaphanous-related formin 1 | -0.0191786 |
| DEK | DEK proto-oncogene | -0.019005 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0189515 |
| PKM | pyruvate kinase, muscle | -0.0188287 |
| MSI2 | musashi RNA-binding protein 2 | -0.0187461 |
| BMP4 | bone morphogenetic protein 4 | -0.0186211 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0184883 |
| SRPK2 | SRSF protein kinase 2 | -0.0184404 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0184324 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0183521 |
| SMIM44 | small integral membrane protein 44 | -0.0182383 |
| HELLS | helicase, lymphoid-specific | -0.0181612 |
| RRM2 | ribonucleotide reductase M2 | -0.0181274 |
