| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.160645 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0989122 |
| MYO1E | myosin IE | 0.0891513 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0870779 |
| RPS12 | ribosomal protein S12 | 0.0732223 |
| RPS6 | ribosomal protein S6 | 0.0711041 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0695932 |
| MT2A | metallothionein 2A | 0.0679564 |
| ENO1 | enolase 1, (alpha) | 0.0639552 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0597021 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0585921 |
| EGFR | epidermal growth factor receptor | 0.0509987 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0504351 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0491973 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0489402 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0473579 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0463209 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0445218 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0401153 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.039224 |
| RPS2 | ribosomal protein S2 | 0.0386145 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0383023 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.036728 |
| MT1X | metallothionein 1X | 0.0363554 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0349837 |
| RPL18 | ribosomal protein L18 | 0.0348728 |
| SVIL | supervillin | 0.0337572 |
| DSPP | dentin sialophosphoprotein | 0.0333794 |
| RPL26 | ribosomal protein L26 | 0.033173 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0327838 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0322222 |
| AREG | amphiregulin | 0.03221 |
| TXNIP | thioredoxin interacting protein | 0.0321847 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0310425 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0309306 |
| B2M | beta-2-microglobulin | 0.029309 |
| MT1E | metallothionein 1E | 0.0292322 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.028212 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0279882 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.027814 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0277257 |
| FOXO1 | forkhead box O1 | 0.02706 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0267646 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0260048 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0256817 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0254127 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0252048 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0247523 |
| NUCB2 | nucleobindin 2 | 0.0238525 |
| KLF6 | Kruppel-like factor 6 | 0.0237503 |
| REEP3 | receptor accessory protein 3 | 0.0236685 |
| FOXP1 | forkhead box P1 | 0.0235805 |
| FTL | ferritin, light polypeptide | 0.0233658 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.023081 |
| RPS19 | ribosomal protein S19 | 0.0230221 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0229586 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0227806 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0227444 |
| RPL8 | ribosomal protein L8 | 0.0227439 |
| AHNAK | AHNAK nucleoprotein | 0.0224939 |
| RNF217 | ring finger protein 217 | 0.0224925 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0223793 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0220494 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0220344 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.021813 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0217255 |
| VCAN | versican | 0.0215759 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0213915 |
| PCDH9 | protocadherin 9 | 0.0213483 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0212249 |
| PLS1 | plastin 1 | 0.0211498 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0210368 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0209546 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0206907 |
| MED13 | mediator complex subunit 13 | 0.0206022 |
| TMC5 | transmembrane channel-like 5 | 0.0204656 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0203021 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0202242 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.020191 |
| PDZD8 | PDZ domain containing 8 | 0.020058 |
| AHI1 | Abelson helper integration site 1 | 0.0199234 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0198826 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0196399 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0196137 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0196044 |
| LMO7 | LIM domain 7 | 0.0195679 |
| RPS3 | ribosomal protein S3 | 0.0194581 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0194071 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0192415 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0190807 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0190306 |
| SET | SET nuclear proto-oncogene | 0.0190289 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0189719 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0189401 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0185508 |
| RPS27 | ribosomal protein S27 | 0.018539 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0184962 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0184133 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0183973 |
| INSR | insulin receptor | 0.0183881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.259853 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.131075 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.128607 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122549 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.107507 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.107119 |
| GPHN | gephyrin | -0.0965053 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0890591 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0890334 |
| VCL | vinculin | -0.0856219 |
| TNS4 | tensin 4 | -0.0793128 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0780287 |
| GOLGA4 | golgin A4 | -0.0767521 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0748765 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0727116 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0629758 |
| TMSB10 | thymosin beta 10 | -0.0628502 |
| ANXA2 | annexin A2 | -0.0627765 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.060064 |
| RNF43 | ring finger protein 43 | -0.0588462 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0527592 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0526044 |
| RPS24 | ribosomal protein S24 | -0.0516323 |
| PKM | pyruvate kinase, muscle | -0.0499324 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0497992 |
| SETD5 | SET domain containing 5 | -0.0492884 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.048291 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0479868 |
| NDRG1 | N-myc downstream regulated 1 | -0.0479632 |
| RBM39 | RNA binding motif protein 39 | -0.0475137 |
| VEGFA | vascular endothelial growth factor A | -0.0467307 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0463279 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0451583 |
| INSIG1 | insulin induced gene 1 | -0.0449501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0449219 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0447192 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0445651 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0435752 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0424962 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0417449 |
| MED13L | mediator complex subunit 13-like | -0.0406958 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0406003 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0403606 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0400784 |
| ACTN4 | actinin, alpha 4 | -0.0400359 |
| TFRC | transferrin receptor | -0.0396392 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0386464 |
| TRIM2 | tripartite motif containing 2 | -0.0384376 |
| USP3 | ubiquitin specific peptidase 3 | -0.0383607 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0377765 |
| HMGA1 | high mobility group AT-hook 1 | -0.0374082 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0372069 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0371456 |
| RRBP1 | ribosome binding protein 1 | -0.0370125 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0368285 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0363655 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0362979 |
| COG5 | component of oligomeric golgi complex 5 | -0.0359902 |
| PCBP2 | poly(rC) binding protein 2 | -0.0359669 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.035961 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0354562 |
| RNF145 | ring finger protein 145 | -0.0352171 |
| FAM13A | family with sequence similarity 13, member A | -0.034698 |
| YBX1 | Y box binding protein 1 | -0.0345861 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342323 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0340607 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0339599 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0338654 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337671 |
| EGR1 | early growth response 1 | -0.0336254 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0333908 |
| FLNB | filamin B, beta | -0.0332556 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0332147 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.033208 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0331878 |
| EREG | epiregulin | -0.0329834 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0327044 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0326946 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0321411 |
| VMP1 | vacuole membrane protein 1 | -0.0321272 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0321219 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0317185 |
| NFIA | nuclear factor I/A | -0.0312709 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0312533 |
| ETNK1 | ethanolamine kinase 1 | -0.0310532 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0310347 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0306312 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0305708 |
| RPL13A | ribosomal protein L13a | -0.0302992 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0301899 |
| ANXA11 | annexin A11 | -0.0301327 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0300953 |
| EZR | ezrin | -0.0300776 |
| NUP58 | nucleoporin 58 | -0.030074 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0300062 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0299382 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0299214 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0296944 |
| FOSL1 | FOS-like antigen 1 | -0.029369 |
| CCNL1 | cyclin L1 | -0.0292494 |
