| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.128115 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.12547 |
| RPS6 | ribosomal protein S6 | 0.107068 |
| CAPRIN2 | caprin family member 2 | 0.0917268 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0865296 |
| DST | dystonin | 0.0850736 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0799911 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0742845 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0740659 |
| RPS12 | ribosomal protein S12 | 0.0661607 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0656409 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0640675 |
| TXNIP | thioredoxin interacting protein | 0.0614583 |
| MT1X | metallothionein 1X | 0.0549265 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0543651 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0525009 |
| SPAG9 | sperm associated antigen 9 | 0.0516781 |
| RUNX1 | runt-related transcription factor 1 | 0.0515131 |
| SQSTM1 | sequestosome 1 | 0.0513028 |
| JMJD1C | jumonji domain containing 1C | 0.0433844 |
| MT1E | metallothionein 1E | 0.0431554 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0429803 |
| RPL26 | ribosomal protein L26 | 0.0427611 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0411636 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0410367 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0405746 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0401486 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0399698 |
| RPS27 | ribosomal protein S27 | 0.0395912 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0393523 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.038853 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.038841 |
| RPL23 | ribosomal protein L23 | 0.0383417 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0382953 |
| USP34 | ubiquitin specific peptidase 34 | 0.0374002 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0363403 |
| PRELID2 | PRELI domain containing 2 | 0.0362167 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0352077 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.035157 |
| MKI67 | marker of proliferation Ki-67 | 0.0346958 |
| IPO7 | importin 7 | 0.0344048 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0342729 |
| SLK | STE20-like kinase | 0.0337843 |
| EREG | epiregulin | 0.0332119 |
| BPTF | bromodomain PHD finger transcription factor | 0.0329354 |
| SYAP1 | synapse associated protein 1 | 0.0329223 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0327545 |
| AREG | amphiregulin | 0.0327046 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0326911 |
| RPS17 | ribosomal protein S17 | 0.0324475 |
| CCDC88A | coiled-coil domain containing 88A | 0.0322053 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0319564 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0315772 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0312732 |
| SON | SON DNA binding protein | 0.0310234 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0309629 |
| VEGFC | vascular endothelial growth factor C | 0.0309337 |
| FNIP1 | folliculin interacting protein 1 | 0.0308821 |
| RCOR1 | REST corepressor 1 | 0.0300279 |
| USP12 | ubiquitin specific peptidase 12 | 0.0299805 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0295147 |
| ARRDC3 | arrestin domain containing 3 | 0.0291941 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0291401 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290259 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0290124 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0284931 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0284619 |
| FMNL2 | formin-like 2 | 0.028153 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0280228 |
| YME1L1 | YME1-like 1 ATPase | 0.0277936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273852 |
| PCNX4 | pecanex 4 | 0.0273133 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0271357 |
| RPS2 | ribosomal protein S2 | 0.0271061 |
| RPL36 | ribosomal protein L36 | 0.0269478 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0269336 |
| SET | SET nuclear proto-oncogene | 0.0269186 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0268376 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0268208 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0263862 |
| HOMER1 | homer scaffolding protein 1 | 0.0263108 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0262801 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.026174 |
| ENO1 | enolase 1, (alpha) | 0.0260805 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0260401 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0256345 |
| INTS6 | integrator complex subunit 6 | 0.0254279 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0252285 |
| VMP1 | vacuole membrane protein 1 | 0.0246009 |
| PHF21A | PHD finger protein 21A | 0.0245562 |
| RPS8 | ribosomal protein S8 | 0.0244343 |
| VCL | vinculin | 0.0243929 |
| ERBIN | erbb2 interacting protein | 0.0242957 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0240999 |
| RPL37 | ribosomal protein L37 | 0.0240214 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0240189 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0239747 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0238565 |
| BRD4 | bromodomain containing 4 | 0.0238287 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0237217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.184755 |
| TMSB10 | thymosin beta 10 | -0.117321 |
| PTMA | prothymosin, alpha | -0.116639 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.109212 |
| CD44 | CD44 molecule (Indian blood group) | -0.105726 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.105002 |
| TMSB4X | thymosin beta 4, X-linked | -0.0966966 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0940064 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0835788 |
| CFAP299 | cilia and flagella associated protein 299 | -0.081519 |
| APP | amyloid beta (A4) precursor protein | -0.077614 |
| HLA-B | major histocompatibility complex, class I, B | -0.0772963 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0690223 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0689634 |
| TNS3 | tensin 3 | -0.067654 |
| RIGI | RNA sensor RIG-I | -0.0612556 |
| POTEF | POTE ankyrin domain family, member F | -0.0606929 |
| LDHA | lactate dehydrogenase A | -0.0585719 |
| CADM2 | cell adhesion molecule 2 | -0.0579825 |
| PGK1 | phosphoglycerate kinase 1 | -0.056583 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.055778 |
| RNF213 | ring finger protein 213 | -0.0508207 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0506185 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0504064 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0500807 |
| ACTG1 | actin gamma 1 | -0.0488332 |
| EFNA5 | ephrin-A5 | -0.0485951 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0447885 |
| PTK2 | protein tyrosine kinase 2 | -0.0444138 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0438135 |
| TP63 | tumor protein p63 | -0.0405435 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0404173 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0390921 |
| ANXA1 | annexin A1 | -0.0384346 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0376775 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.037477 |
| EXOC4 | exocyst complex component 4 | -0.0370915 |
| RPS24 | ribosomal protein S24 | -0.0359693 |
| FTL | ferritin, light polypeptide | -0.0356053 |
| EHBP1 | EH domain binding protein 1 | -0.0355028 |
| COL5A2 | collagen, type V, alpha 2 | -0.0345119 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0333693 |
| CAVIN1 | caveolae associated protein 1 | -0.032578 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0322421 |
| S100A6 | S100 calcium binding protein A6 | -0.0322168 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0320335 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0314974 |
| RAD51B | RAD51 paralog B | -0.0311279 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0305363 |
| TAPBP | TAP binding protein (tapasin) | -0.0304687 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0299667 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0297935 |
| RPS27A | ribosomal protein S27a | -0.0295093 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0294951 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0294812 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0293422 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0292418 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0288603 |
| LRRC49 | leucine rich repeat containing 49 | -0.0287063 |
| RGS4 | regulator of G-protein signaling 4 | -0.0284221 |
| SBF2 | SET binding factor 2 | -0.0283226 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0282514 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0274952 |
| RBM25 | RNA binding motif protein 25 | -0.0273022 |
| ANXA2 | annexin A2 | -0.0268034 |
| TPM4 | tropomyosin 4 | -0.0256294 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0254575 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0254071 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0253508 |
| SMYD3 | SET and MYND domain containing 3 | -0.02525 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0251679 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0246507 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0245022 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0243836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0243179 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0242986 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0239394 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0239128 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0238501 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0235141 |
| GNAS | GNAS complex locus | -0.023442 |
| SYT1 | synaptotagmin I | -0.0232292 |
| HLA-E | major histocompatibility complex, class I, E | -0.0230525 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0229175 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0228431 |
| RPL7A | ribosomal protein L7a | -0.0220706 |
| EPHA4 | EPH receptor A4 | -0.0218526 |
| RAI1 | retinoic acid induced 1 | -0.0218443 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0216031 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.021514 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0214297 |
| HLA-A | major histocompatibility complex, class I, A | -0.0214279 |
| TFRC | transferrin receptor | -0.0213648 |
| SRGN | serglycin | -0.0212598 |
| ENOSF1 | enolase superfamily member 1 | -0.0210882 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0210548 |
| SUMF1 | sulfatase modifying factor 1 | -0.0209382 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208124 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0208019 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0207271 |
