| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.242684 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0880815 |
| NTN4 | netrin 4 | 0.0791761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.077202 |
| HMGA2 | high mobility group AT-hook 2 | 0.064392 |
| GLCCI1 | glucocorticoid induced 1 | 0.0573611 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.057147 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0555873 |
| FTL | ferritin, light polypeptide | 0.0538991 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0517979 |
| MT2A | metallothionein 2A | 0.0495208 |
| RPS6 | ribosomal protein S6 | 0.0483417 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0464102 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0440721 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0440328 |
| WLS | wntless Wnt ligand secretion mediator | 0.0432562 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0429741 |
| ECE1 | endothelin converting enzyme 1 | 0.0417916 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0413555 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0399274 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0397289 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0394951 |
| ZNF638 | zinc finger protein 638 | 0.0393691 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0390558 |
| INTS6 | integrator complex subunit 6 | 0.0389921 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.03751 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0356561 |
| AADAC | arylacetamide deacetylase | 0.0348205 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0345051 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0338989 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0326763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0326593 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0324666 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0318065 |
| SQSTM1 | sequestosome 1 | 0.0311508 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0308147 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0306384 |
| SYT1 | synaptotagmin I | 0.0305946 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0304042 |
| TXNIP | thioredoxin interacting protein | 0.0294414 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0293313 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0291963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.029147 |
| MED13 | mediator complex subunit 13 | 0.0286804 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0286645 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0281407 |
| FBXO11 | F-box protein 11 | 0.0281153 |
| IL1R1 | interleukin 1 receptor, type I | 0.0280736 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278452 |
| BPTF | bromodomain PHD finger transcription factor | 0.0275255 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0270081 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.026891 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0266688 |
| PLIN2 | perilipin 2 | 0.0266166 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0266076 |
| RPS8 | ribosomal protein S8 | 0.0265994 |
| RDX | radixin | 0.0262999 |
| LAMA4 | laminin, alpha 4 | 0.0262013 |
| RPS19 | ribosomal protein S19 | 0.025904 |
| FNIP2 | folliculin interacting protein 2 | 0.0257719 |
| OXSR1 | oxidative stress responsive 1 | 0.0253052 |
| STK38L | serine/threonine kinase 38 like | 0.025139 |
| SVIL | supervillin | 0.0245237 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0241713 |
| SFTPA2 | surfactant protein A2 | 0.0238287 |
| FN1 | fibronectin 1 | 0.0236801 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0236685 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0234766 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0234754 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0232614 |
| IFI44L | interferon-induced protein 44-like | 0.0231423 |
| RPLP1 | ribosomal protein, large, P1 | 0.0228881 |
| KSR1 | kinase suppressor of ras 1 | 0.0228328 |
| KYNU | kynureninase | 0.0228324 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0228081 |
| RHCG | Rh family, C glycoprotein | 0.0227477 |
| RIOK3 | RIO kinase 3 | 0.0225864 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0225208 |
| B2M | beta-2-microglobulin | 0.0222296 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0221477 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0221157 |
| ENO1 | enolase 1, (alpha) | 0.0220922 |
| PHF14 | PHD finger protein 14 | 0.0217571 |
| RNF24 | ring finger protein 24 | 0.0214763 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0214554 |
| CPM | carboxypeptidase M | 0.0214552 |
| RPL34 | ribosomal protein L34 | 0.0213088 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0211092 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0209094 |
| IL6ST | interleukin 6 signal transducer | 0.0208607 |
| RNF144A | ring finger protein 144A | 0.0200384 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0198699 |
| SYAP1 | synapse associated protein 1 | 0.0196351 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0195814 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0195609 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0195091 |
| KLHL24 | kelch-like family member 24 | 0.0194994 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0194284 |
| RPS27 | ribosomal protein S27 | 0.0193521 |
| STAG2 | stromal antigen 2 | 0.0191867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.181712 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.181705 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.137464 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.130412 |
| FNDC3B | fibronectin type III domain containing 3B | -0.112277 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.100429 |
| CDH13 | cadherin 13 | -0.100254 |
| OSMR | oncostatin M receptor | -0.0951274 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0885168 |
| TMSB10 | thymosin beta 10 | -0.0817421 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0782176 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0761846 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0735461 |
| GPC6 | glypican 6 | -0.0723616 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0690689 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0681688 |
| EFNA5 | ephrin-A5 | -0.0679565 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0640793 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0637281 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0612989 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0581308 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0554681 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.054537 |
| LOX | lysyl oxidase | -0.0538328 |
| FAM20C | family with sequence similarity 20, member C | -0.0534322 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0526716 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0514025 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0513814 |
| NBAS | neuroblastoma amplified sequence | -0.0497777 |
| CDCP1 | CUB domain containing protein 1 | -0.0493306 |
| NDRG1 | N-myc downstream regulated 1 | -0.0492745 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0488557 |
| CD44 | CD44 molecule (Indian blood group) | -0.0488013 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.048728 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0459769 |
| VEGFA | vascular endothelial growth factor A | -0.0458653 |
| USP34 | ubiquitin specific peptidase 34 | -0.0429802 |
| DNER | delta/notch-like EGF repeat containing | -0.0424194 |
| NRG1 | neuregulin 1 | -0.0422032 |
| STC1 | stanniocalcin 1 | -0.0411177 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0403798 |
| EXOC4 | exocyst complex component 4 | -0.0403791 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0402904 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0401161 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0396467 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0393352 |
| LRRC49 | leucine rich repeat containing 49 | -0.0383713 |
| NAV3 | neuron navigator 3 | -0.038083 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0378429 |
| MTSS1 | metastasis suppressor 1 | -0.0374013 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0372266 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0369077 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0367033 |
| ATG7 | autophagy related 7 | -0.0365991 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0364418 |
| AK1 | adenylate kinase 1 | -0.0360483 |
| EGFR | epidermal growth factor receptor | -0.0359454 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0358059 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0355917 |
| DENND1A | DENN/MADD domain containing 1A | -0.0343093 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0339829 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0337858 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0334857 |
| PCBP2 | poly(rC) binding protein 2 | -0.0334475 |
| TMEM165 | transmembrane protein 165 | -0.0331228 |
| ZNF292 | zinc finger protein 292 | -0.0328275 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0327018 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0325873 |
| RBM39 | RNA binding motif protein 39 | -0.0325726 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0324304 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0323269 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0323039 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0322824 |
| FRMD4A | FERM domain containing 4A | -0.0318222 |
| ATP13A3 | ATPase type 13A3 | -0.0316929 |
| SLC43A3 | solute carrier family 43, member 3 | -0.031496 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0314282 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.031369 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0311711 |
| PARD3 | par-3 family cell polarity regulator | -0.0311406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0310548 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0310052 |
| CTNNBL1 | catenin, beta like 1 | -0.0309626 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0305801 |
| COG5 | component of oligomeric golgi complex 5 | -0.030563 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0302904 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0295186 |
| DYM | dymeclin | -0.029409 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0293693 |
| TMEM131 | transmembrane protein 131 | -0.0291509 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0290554 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0281897 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0281623 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0280152 |
| HPCAL1 | hippocalcin-like 1 | -0.0276815 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0275761 |
| METTL15 | methyltransferase like 15 | -0.0274043 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0268888 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0268403 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0265782 |
