| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.0935049 |
| MT2A | metallothionein 2A | 0.0796216 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0693627 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0693232 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0636617 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0587051 |
| RPL23 | ribosomal protein L23 | 0.0578576 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0527834 |
| RPS6 | ribosomal protein S6 | 0.0495934 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0485543 |
| RBM39 | RNA binding motif protein 39 | 0.0447264 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0445606 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444304 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0437432 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0392322 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0386853 |
| RPS12 | ribosomal protein S12 | 0.0383682 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.038137 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0369994 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0360326 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0335262 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0328004 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317108 |
| KIF5B | kinesin family member 5B | 0.0309562 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0305341 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0304081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0294696 |
| NNMT | nicotinamide N-methyltransferase | 0.0284624 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0281651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0279467 |
| MED13 | mediator complex subunit 13 | 0.0278511 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0278309 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0264034 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0260017 |
| RPS8 | ribosomal protein S8 | 0.025978 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025808 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0257405 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.025571 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0253746 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.025196 |
| RPS19 | ribosomal protein S19 | 0.0247333 |
| RPS17 | ribosomal protein S17 | 0.0245439 |
| PCBP2 | poly(rC) binding protein 2 | 0.0242593 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0241383 |
| RPL37A | ribosomal protein L37a | 0.0240685 |
| CCNL1 | cyclin L1 | 0.0236852 |
| ZNF207 | zinc finger protein 207 | 0.0235257 |
| TFG | TRK-fused gene | 0.0235161 |
| CUL3 | cullin 3 | 0.0234153 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0230929 |
| INTS6 | integrator complex subunit 6 | 0.0230735 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0230076 |
| SON | SON DNA binding protein | 0.0226659 |
| BRD2 | bromodomain containing 2 | 0.0224962 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0223967 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0219601 |
| MT1X | metallothionein 1X | 0.021907 |
| SIK3 | SIK family kinase 3 | 0.0219065 |
| NCKAP1 | NCK-associated protein 1 | 0.0215638 |
| RNF145 | ring finger protein 145 | 0.0215249 |
| TOP1 | topoisomerase (DNA) I | 0.0213658 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.021128 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0211064 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0210828 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0208039 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0204835 |
| NOP58 | NOP58 ribonucleoprotein | 0.0203774 |
| NUP98 | nucleoporin 98kDa | 0.0202329 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0201809 |
| FUS | FUS RNA binding protein | 0.0201192 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0201083 |
| TPM3 | tropomyosin 3 | 0.0200709 |
| TPD52 | tumor protein D52 | 0.0199997 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0198183 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0197378 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.019613 |
| FOXO3 | forkhead box O3 | 0.0192813 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.019266 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0191481 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0190346 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0188208 |
| PAPOLA | poly(A) polymerase alpha | 0.018775 |
| SPAG9 | sperm associated antigen 9 | 0.018664 |
| KYNU | kynureninase | 0.0186026 |
| RPL26 | ribosomal protein L26 | 0.018457 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0184499 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0183925 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0183415 |
| COPA | coatomer protein complex, subunit alpha | 0.018255 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0182274 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0181328 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0179239 |
| RPS2 | ribosomal protein S2 | 0.017907 |
| USP36 | ubiquitin specific peptidase 36 | 0.0178599 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0178334 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0177796 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0177557 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.017685 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0175704 |
| GOLGA4 | golgin A4 | 0.0175626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.285879 |
| GRAMD1B | GRAM domain containing 1B | -0.151592 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.114322 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.114109 |
| TXNRD1 | thioredoxin reductase 1 | -0.0983449 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0696367 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0632704 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0588249 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0562234 |
| PYGL | phosphorylase, glycogen, liver | -0.0535476 |
| TPM4 | tropomyosin 4 | -0.0525472 |
| CMIP | c-Maf inducing protein | -0.0513035 |
| VIM | vimentin | -0.051238 |
| BICC1 | BicC family RNA binding protein 1 | -0.0510508 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0469472 |
| LDHA | lactate dehydrogenase A | -0.0467976 |
| HDAC9 | histone deacetylase 9 | -0.0466165 |
| NAV3 | neuron navigator 3 | -0.0445068 |
| ACTG1 | actin gamma 1 | -0.042941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0396139 |
| EGR1 | early growth response 1 | -0.0377606 |
| RAD51B | RAD51 paralog B | -0.0371399 |
| CAVIN1 | caveolae associated protein 1 | -0.0333987 |
| SVIL | supervillin | -0.0333368 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0331344 |
| ASPH | aspartate beta-hydroxylase | -0.0327548 |
| S100A6 | S100 calcium binding protein A6 | -0.0326962 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0326899 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0317828 |
| OSMR | oncostatin M receptor | -0.0311403 |
| GLIS3 | GLIS family zinc finger 3 | -0.030905 |
| AK1 | adenylate kinase 1 | -0.030232 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0291333 |
| IER3 | immediate early response 3 | -0.0289155 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0287293 |
| NRG1 | neuregulin 1 | -0.0284728 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0261006 |
| PTMA | prothymosin, alpha | -0.0257187 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0248234 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0239059 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0237604 |
| EGFR | epidermal growth factor receptor | -0.0235956 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0232607 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0225591 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0222313 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0219855 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0218237 |
| POTEF | POTE ankyrin domain family, member F | -0.0216317 |
| NEBL | nebulette | -0.0211725 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0210294 |
| NEGR1 | neuronal growth regulator 1 | -0.020947 |
| WWOX | WW domain containing oxidoreductase | -0.0207854 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0205156 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.020114 |
| MAP1B | microtubule-associated protein 1B | -0.0201099 |
| SEPTIN10 | septin 10 | -0.020087 |
| EXOC4 | exocyst complex component 4 | -0.02003 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199729 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.01964 |
| DST | dystonin | -0.0193334 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0193245 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0188221 |
| CD44 | CD44 molecule (Indian blood group) | -0.0187001 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0184373 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0178341 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0178285 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.017772 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0177588 |
| LAMC2 | laminin, gamma 2 | -0.0172912 |
| FOXP1 | forkhead box P1 | -0.0168774 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0166172 |
| APP | amyloid beta (A4) precursor protein | -0.0165066 |
| ANXA2 | annexin A2 | -0.016479 |
| DNMBP | dynamin binding protein | -0.0161927 |
| RSPO3 | R-spondin 3 | -0.0161903 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0160881 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0160825 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0158376 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0157834 |
| FHIT | fragile histidine triad | -0.0154473 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0154153 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.015312 |
| IGF2 | insulin-like growth factor 2 | -0.0149879 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0149236 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0149229 |
| TPM1 | tropomyosin 1 (alpha) | -0.0148301 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0148055 |
| IL6 | interleukin 6 | -0.0147153 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0145543 |
| CFDP1 | craniofacial development protein 1 | -0.0145507 |
| RIN2 | Ras and Rab interactor 2 | -0.0145166 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0141775 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0141529 |
| THBS1 | thrombospondin 1 | -0.0140832 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0140648 |
| BMP5 | bone morphogenetic protein 5 | -0.0140367 |
| KLF6 | Kruppel-like factor 6 | -0.0140246 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0138669 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0138231 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0137539 |
