| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vilanterol_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.141201 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.128353 |
| MYO1E | myosin IE | 0.111206 |
| DSCAM | Down syndrome cell adhesion molecule | 0.105146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0810822 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0792589 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0768806 |
| STC1 | stanniocalcin 1 | 0.0759238 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0705946 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0648653 |
| PLAUR | plasminogen activator, urokinase receptor | 0.06437 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0628098 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.062773 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0620597 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0610473 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0609074 |
| LAMB3 | laminin, beta 3 | 0.0607384 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0605396 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0594474 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0561391 |
| EZR | ezrin | 0.0538356 |
| KATNBL1 | katanin p80 subunit B-like 1 | 0.0513432 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.049508 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0494702 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0489559 |
| KLF6 | Kruppel-like factor 6 | 0.0488971 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0487569 |
| IGF2 | insulin-like growth factor 2 | 0.0487402 |
| LAMC2 | laminin, gamma 2 | 0.0486886 |
| LMO7 | LIM domain 7 | 0.0474382 |
| MYO5B | myosin VB | 0.0473433 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0473152 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0467315 |
| NDRG1 | N-myc downstream regulated 1 | 0.0462278 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0461084 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0455437 |
| KYNU | kynureninase | 0.0454049 |
| EFNA5 | ephrin-A5 | 0.0443439 |
| MXD1 | MAX dimerization protein 1 | 0.0441539 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0439906 |
| ABHD17C | abhydrolase domain containing 17C | 0.0438409 |
| RNF145 | ring finger protein 145 | 0.0431995 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0417996 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0415923 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0411053 |
| TUSC3 | tumor suppressor candidate 3 | 0.040733 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.040731 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0406039 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0405831 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0403311 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.039405 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0393396 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0390222 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0382944 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0381195 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0380707 |
| PHF3 | PHD finger protein 3 | 0.0378871 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0370275 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0369932 |
| VMP1 | vacuole membrane protein 1 | 0.0369021 |
| H3-3B | H3.3 histone B | 0.0365767 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0363921 |
| CDC73 | cell division cycle 73 | 0.036219 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0361357 |
| RBM39 | RNA binding motif protein 39 | 0.0355495 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.035522 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0354168 |
| NUP153 | nucleoporin 153kDa | 0.035362 |
| EP300 | E1A binding protein p300 | 0.0353462 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0338247 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0337918 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0334076 |
| DSPP | dentin sialophosphoprotein | 0.0333399 |
| IRS2 | insulin receptor substrate 2 | 0.0333196 |
| INTS6 | integrator complex subunit 6 | 0.0329567 |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.0324679 |
| TJP1 | tight junction protein 1 | 0.0321532 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0321198 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0320895 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.032078 |
| MYO1B | myosin IB | 0.0320062 |
| FOXO1 | forkhead box O1 | 0.031976 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0316584 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0315057 |
| PTGES2 | prostaglandin E synthase 2 | 0.0311987 |
| ANXA1 | annexin A1 | 0.031057 |
| NHSL1 | NHS-like 1 | 0.031016 |
| DIAPH1 | diaphanous-related formin 1 | 0.0309672 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0308309 |
| GRAMD2B | GRAM domain containing 2B | 0.0307822 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0301205 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.029955 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0295768 |
| TPI1 | triosephosphate isomerase 1 | 0.0294047 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0292962 |
| SBF2 | SET binding factor 2 | 0.0292163 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0291779 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0288077 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.028615 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0284154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.084102 |
| TMSB10 | thymosin beta 10 | -0.0648301 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0628259 |
| EGR1 | early growth response 1 | -0.0621741 |
| ASPH | aspartate beta-hydroxylase | -0.062075 |
| TMEM165 | transmembrane protein 165 | -0.0615938 |
| DST | dystonin | -0.057111 |
| USP34 | ubiquitin specific peptidase 34 | -0.056335 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0537715 |
| LSAMP | limbic system-associated membrane protein | -0.0532474 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0532021 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0509739 |
| SETD5 | SET domain containing 5 | -0.0507474 |
| FLNB | filamin B, beta | -0.0505857 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0492251 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0481589 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0480263 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0466312 |
| RBM25 | RNA binding motif protein 25 | -0.0457296 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0457181 |
| SRPK2 | SRSF protein kinase 2 | -0.0441049 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.044037 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0433394 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0429961 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0429398 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0424533 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0420371 |
| RPL23 | ribosomal protein L23 | -0.0414781 |
| FMNL2 | formin-like 2 | -0.0410722 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0401052 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0398634 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0396638 |
| TXNIP | thioredoxin interacting protein | -0.0396472 |
| CALR | calreticulin | -0.0393048 |
| TLK1 | tousled-like kinase 1 | -0.0388677 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.038411 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0383963 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0381852 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0380186 |
| SLTM | SAFB-like, transcription modulator | -0.037825 |
| MRTFA | myocardin related transcription factor A | -0.0377285 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0369427 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0362314 |
| NBEAL1 | neurobeachin-like 1 | -0.036191 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0354355 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.035088 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0349141 |
| ZNF638 | zinc finger protein 638 | -0.034683 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0344938 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0342452 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0340673 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0333579 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0332622 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0331843 |
| FNBP1 | formin binding protein 1 | -0.0328955 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0325532 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0324409 |
| RSF1 | remodeling and spacing factor 1 | -0.0323876 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0320318 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0319038 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0318183 |
| DSG2 | desmoglein 2 | -0.0317648 |
| DMXL2 | Dmx-like 2 | -0.0317179 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0316777 |
| NUP58 | nucleoporin 58 | -0.0316288 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0314138 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0311471 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0309346 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0309188 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0308922 |
| MTDH | metadherin | -0.0304298 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0302586 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0301281 |
| RPL18 | ribosomal protein L18 | -0.0300873 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0297719 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0297391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0296346 |
| RIGI | RNA sensor RIG-I | -0.0296077 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0295555 |
| SPAG9 | sperm associated antigen 9 | -0.029553 |
| S100A11 | S100 calcium binding protein A11 | -0.0295426 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0295001 |
| SEPTIN9 | septin 9 | -0.0289149 |
| EHBP1 | EH domain binding protein 1 | -0.0286843 |
| DIAPH2 | diaphanous-related formin 2 | -0.0286712 |
| SEPTIN7 | septin 7 | -0.0286666 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.028345 |
| RPS27A | ribosomal protein S27a | -0.0283201 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0281721 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0281548 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0279418 |
| GLG1 | golgi glycoprotein 1 | -0.027727 |
| ZFR | zinc finger RNA binding protein | -0.0276907 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0275126 |
| FOSL1 | FOS-like antigen 1 | -0.0273125 |
| PDE8A | phosphodiesterase 8A | -0.0271989 |
| JUN | jun proto-oncogene | -0.0271941 |
| RPS4X | ribosomal protein S4, X-linked | -0.0270716 |
| LASP1 | LIM and SH3 protein 1 | -0.027034 |
| POTEF | POTE ankyrin domain family, member F | -0.0270105 |
