| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.220701 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0807154 |
| TXNRD1 | thioredoxin reductase 1 | 0.0789045 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0555918 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.049707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0457825 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0447123 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0439937 |
| YBX3 | Y box binding protein 3 | 0.0436409 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0419329 |
| JMJD1C | jumonji domain containing 1C | 0.0413371 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0411862 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.037029 |
| FBXO11 | F-box protein 11 | 0.035416 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0324235 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0323291 |
| HOMER1 | homer scaffolding protein 1 | 0.0320739 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0317926 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0310188 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303036 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303035 |
| TMEM41B | transmembrane protein 41B | 0.0300339 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.029761 |
| STC1 | stanniocalcin 1 | 0.0295186 |
| OGA | O-GlcNAcase | 0.0290199 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0279453 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265914 |
| SET | SET nuclear proto-oncogene | 0.025668 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0254668 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0253154 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0250378 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.024631 |
| RPL37A | ribosomal protein L37a | 0.0244647 |
| ADIPOR2 | adiponectin receptor 2 | 0.0236726 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0236275 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0235555 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0230617 |
| ERBIN | erbb2 interacting protein | 0.022901 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0225602 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.0222906 |
| STK4 | serine/threonine kinase 4 | 0.0222615 |
| PREPL | prolyl endopeptidase-like | 0.0221501 |
| IER3 | immediate early response 3 | 0.0220671 |
| RPS6 | ribosomal protein S6 | 0.0220018 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0217694 |
| SQSTM1 | sequestosome 1 | 0.0215799 |
| R3HDM2 | R3H domain containing 2 | 0.0213983 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0212257 |
| XPOT | exportin, tRNA | 0.0209193 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207766 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0202589 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.020232 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0202054 |
| TUT7 | terminal uridylyl transferase 7 | 0.0194887 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0194166 |
| KLF6 | Kruppel-like factor 6 | 0.0193383 |
| RPS12 | ribosomal protein S12 | 0.0192704 |
| MYPN | myopalladin | 0.0192493 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0191986 |
| TPM2 | tropomyosin 2 (beta) | 0.019055 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0189683 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0189352 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.018868 |
| CTTN | cortactin | 0.0188262 |
| FAM199X | family with sequence similarity 199, X-linked | 0.0186298 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.018043 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0178814 |
| RNF145 | ring finger protein 145 | 0.0177572 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0176103 |
| GPHN | gephyrin | 0.0175523 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0174006 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0170879 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0170727 |
| DST | dystonin | 0.0170025 |
| CREM | cAMP responsive element modulator | 0.0169472 |
| RPS3 | ribosomal protein S3 | 0.0168796 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0168111 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0167683 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0167556 |
| LUZP1 | leucine zipper protein 1 | 0.0167172 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0164824 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0164558 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0162525 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0161804 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0161531 |
| TJP1 | tight junction protein 1 | 0.0160646 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0159627 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0158517 |
| CAPRIN2 | caprin family member 2 | 0.0158232 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0158207 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0157459 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0157046 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.0152747 |
| NRG1 | neuregulin 1 | 0.0152189 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0150929 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0150653 |
| RPS8 | ribosomal protein S8 | 0.0149078 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0148605 |
| HMOX1 | heme oxygenase 1 | 0.0148406 |
| MYO10 | myosin X | 0.014754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171584 |
| RAD51B | RAD51 paralog B | -0.148791 |
| EGR1 | early growth response 1 | -0.134147 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.123415 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.11906 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0938924 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0875386 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0830267 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0709209 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0702361 |
| ATXN1 | ataxin 1 | -0.0636096 |
| PTMA | prothymosin, alpha | -0.0631561 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0630935 |
| TAPBP | TAP binding protein (tapasin) | -0.0618053 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0615005 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0600174 |
| EXOC4 | exocyst complex component 4 | -0.0588898 |
| SMAD3 | SMAD family member 3 | -0.0577736 |
| BBX | bobby sox homolog (Drosophila) | -0.0570084 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0568541 |
| TMSB10 | thymosin beta 10 | -0.0547236 |
| PYGL | phosphorylase, glycogen, liver | -0.0539816 |
| POTEF | POTE ankyrin domain family, member F | -0.0534009 |
| RYR3 | ryanodine receptor 3 | -0.0532572 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0509533 |
| USP34 | ubiquitin specific peptidase 34 | -0.0504264 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0497103 |
| PTK2 | protein tyrosine kinase 2 | -0.0496108 |
| HMGA2 | high mobility group AT-hook 2 | -0.0490481 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.048638 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0479083 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0474293 |
| SBF2 | SET binding factor 2 | -0.0470628 |
| RNF213 | ring finger protein 213 | -0.0469305 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0464915 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0464554 |
| LDHA | lactate dehydrogenase A | -0.0448062 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0446215 |
| ADAR | adenosine deaminase, RNA-specific | -0.0445123 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.044041 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.043911 |
| DENND1A | DENN/MADD domain containing 1A | -0.0435796 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.043054 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.042998 |
| NCOA7 | nuclear receptor coactivator 7 | -0.042248 |
| OSMR | oncostatin M receptor | -0.0419492 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0419153 |
| PCBP2 | poly(rC) binding protein 2 | -0.0418146 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0408464 |
| VIM | vimentin | -0.0404122 |
| EGFR | epidermal growth factor receptor | -0.0403922 |
| PDE10A | phosphodiesterase 10A | -0.0400471 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0384023 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0382262 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0380939 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0378719 |
| PFN1 | profilin 1 | -0.0378282 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0377844 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0368111 |
| BSG | basigin (Ok blood group) | -0.0362795 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0362722 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0358159 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0353267 |
| YBX1 | Y box binding protein 1 | -0.0347598 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0345976 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0341504 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.034082 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0340424 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0339553 |
| GRAMD1B | GRAM domain containing 1B | -0.0338533 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0332132 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0325722 |
| PARD3 | par-3 family cell polarity regulator | -0.0315553 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0310232 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0309408 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0305898 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.030473 |
| RPLP0 | ribosomal protein, large, P0 | -0.0300615 |
| TPI1 | triosephosphate isomerase 1 | -0.0298875 |
| TAOK1 | TAO kinase 1 | -0.0297321 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0295002 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0292034 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0291482 |
| CCND2 | cyclin D2 | -0.0290583 |
| AGRN | agrin | -0.0290532 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0288035 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0285009 |
| COPA | coatomer protein complex, subunit alpha | -0.0284502 |
| FMN1 | formin 1 | -0.0282733 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0280199 |
| CCNL1 | cyclin L1 | -0.0276743 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0276076 |
| NBAS | neuroblastoma amplified sequence | -0.027435 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0271863 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268565 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.026784 |
| AEBP2 | AE binding protein 2 | -0.0267268 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0266727 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.026479 |
| NABP1 | nucleic acid binding protein 1 | -0.0262772 |
