| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.173141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.135805 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.119367 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.10501 |
| EFNA5 | ephrin-A5 | 0.0724827 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0679311 |
| STEAP4 | STEAP family member 4 | 0.0660985 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0653789 |
| LMO7 | LIM domain 7 | 0.0623899 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0591216 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0483054 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0473999 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0442285 |
| HMGB2 | high mobility group box 2 | 0.0422489 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0389266 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0372596 |
| ASPH | aspartate beta-hydroxylase | 0.0372141 |
| TXNIP | thioredoxin interacting protein | 0.035903 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0344298 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0329265 |
| ARRDC3 | arrestin domain containing 3 | 0.032696 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0302038 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0295988 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0286882 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0281855 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0277379 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0273885 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0272355 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0259695 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0255248 |
| GRAMD2B | GRAM domain containing 2B | 0.0250167 |
| CCNI | cyclin I | 0.0249476 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0248399 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0247152 |
| SGMS2 | sphingomyelin synthase 2 | 0.0245212 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0242478 |
| EGFR | epidermal growth factor receptor | 0.0241768 |
| OCLN | occludin | 0.0236326 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0226996 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0225309 |
| RASAL2 | RAS protein activator like 2 | 0.0224314 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0222242 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0219399 |
| CTSB | cathepsin B | 0.0218412 |
| NTN4 | netrin 4 | 0.0216543 |
| PALLD | palladin, cytoskeletal associated protein | 0.0212368 |
| PARD3 | par-3 family cell polarity regulator | 0.0207473 |
| ENO1 | enolase 1, (alpha) | 0.0206848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0206561 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0202296 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0201011 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0200869 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0200785 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0200663 |
| MKI67 | marker of proliferation Ki-67 | 0.0199008 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0194128 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0193077 |
| EREG | epiregulin | 0.0191877 |
| SMIM14 | small integral membrane protein 14 | 0.019071 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0190488 |
| OSMR | oncostatin M receptor | 0.0189393 |
| TMEM263 | transmembrane protein 263 | 0.0189319 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.018796 |
| FCHO2 | FCH domain only 2 | 0.018615 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0179463 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.017363 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0172091 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0170807 |
| SHROOM3 | shroom family member 3 | 0.01688 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0167089 |
| UBC | ubiquitin C | 0.0166765 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0165779 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0164301 |
| ATXN1 | ataxin 1 | 0.0163308 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.016234 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0162193 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0162165 |
| AREG | amphiregulin | 0.0161574 |
| KLF6 | Kruppel-like factor 6 | 0.0159596 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0156343 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0155703 |
| VGLL3 | vestigial-like family member 3 | 0.0152967 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0152027 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0147554 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0144866 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0144785 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0144313 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0144018 |
| AOPEP | aminopeptidase O (putative) | 0.0143687 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0143241 |
| HOMER2 | homer scaffolding protein 2 | 0.014291 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0141389 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0141334 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0140214 |
| VCL | vinculin | 0.0140014 |
| JMJD1C | jumonji domain containing 1C | 0.0139448 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0139221 |
| TRIM2 | tripartite motif containing 2 | 0.0138754 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0138126 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0138072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.249294 |
| FTL | ferritin, light polypeptide | -0.159026 |
| PTMA | prothymosin, alpha | -0.139228 |
| NDRG1 | N-myc downstream regulated 1 | -0.128052 |
| GRB10 | growth factor receptor-bound protein 10 | -0.126927 |
| ACTG1 | actin gamma 1 | -0.1127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0922793 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0896616 |
| DTNA | dystrobrevin, alpha | -0.0845182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0754909 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0748814 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0722277 |
| TMSB10 | thymosin beta 10 | -0.0710597 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0671931 |
| TPM4 | tropomyosin 4 | -0.0666278 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0650874 |
| HMGA1 | high mobility group AT-hook 1 | -0.0624445 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0620178 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0619337 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.059301 |
| VEGFA | vascular endothelial growth factor A | -0.0591288 |
| PTK2 | protein tyrosine kinase 2 | -0.0584037 |
| CCND1 | cyclin D1 | -0.0583242 |
| MAP1B | microtubule-associated protein 1B | -0.0525696 |
| FOSL1 | FOS-like antigen 1 | -0.0519417 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0514249 |
| RBM25 | RNA binding motif protein 25 | -0.050756 |
| PKM | pyruvate kinase, muscle | -0.0505913 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0488911 |
| CSTB | cystatin B (stefin B) | -0.0488764 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0482241 |
| S100A6 | S100 calcium binding protein A6 | -0.0469103 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0465067 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0463399 |
| PCBP2 | poly(rC) binding protein 2 | -0.0449512 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0445064 |
| LDHA | lactate dehydrogenase A | -0.044077 |
| MEF2A | myocyte enhancer factor 2A | -0.0440484 |
| RBM39 | RNA binding motif protein 39 | -0.0437953 |
| FNDC3B | fibronectin type III domain containing 3B | -0.043755 |
| G0S2 | G0/G1 switch 2 | -0.0431244 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0425944 |
| HLA-B | major histocompatibility complex, class I, B | -0.0420933 |
| RPL35A | ribosomal protein L35a | -0.0420485 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0419855 |
| ZNF292 | zinc finger protein 292 | -0.0417925 |
| MSI2 | musashi RNA-binding protein 2 | -0.0417542 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0413916 |
| PLEC | plectin | -0.0413259 |
| FAM3C | family with sequence similarity 3, member C | -0.0410285 |
| LMNA | lamin A/C | -0.0409817 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0407772 |
| WASF2 | WAS protein family, member 2 | -0.0404497 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0403688 |
| PLAU | plasminogen activator, urokinase | -0.0395126 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0390798 |
| TMSB4X | thymosin beta 4, X-linked | -0.0370789 |
| HLA-A | major histocompatibility complex, class I, A | -0.0362551 |
| CERT1 | ceramide transporter 1 | -0.0358739 |
| VIM | vimentin | -0.0357373 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0355888 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0354309 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0353915 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0352796 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0351804 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0350535 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0349725 |
| JUP | junction plakoglobin | -0.0346965 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0336326 |
| FN1 | fibronectin 1 | -0.0335336 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.033294 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0331177 |
| TPM3 | tropomyosin 3 | -0.0329173 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0328729 |
| CD109 | CD109 molecule | -0.0327061 |
| MSN | moesin | -0.0325784 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0324723 |
| HDGF | hepatoma-derived growth factor | -0.0315635 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0313447 |
| RCOR1 | REST corepressor 1 | -0.0313184 |
| FBXO32 | F-box protein 32 | -0.0308612 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.02989 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0298895 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.02987 |
| S100A10 | S100 calcium binding protein A10 | -0.0295381 |
| SLMAP | sarcolemma associated protein | -0.0292766 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0291184 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0289815 |
| MYO6 | myosin VI | -0.0285449 |
| USP3 | ubiquitin specific peptidase 3 | -0.028485 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0281827 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0275218 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0273195 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0272391 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.026891 |
| RPLP1 | ribosomal protein, large, P1 | -0.0268192 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0267524 |
| EGR1 | early growth response 1 | -0.0264475 |
| ATP11B | ATPase, class VI, type 11B | -0.0262881 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0262143 |
