| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.148955 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.10754 |
| RPS12 | ribosomal protein S12 | 0.103241 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0946398 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0916251 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0832742 |
| RPS6 | ribosomal protein S6 | 0.0780139 |
| RPL26 | ribosomal protein L26 | 0.0710538 |
| RPS8 | ribosomal protein S8 | 0.0704344 |
| RPS3 | ribosomal protein S3 | 0.0686172 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0637063 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0635398 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0601718 |
| RPL37A | ribosomal protein L37a | 0.0578058 |
| SQSTM1 | sequestosome 1 | 0.0566852 |
| FMNL2 | formin-like 2 | 0.0561888 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0554013 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0537624 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0530386 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.052292 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0496538 |
| PRELID2 | PRELI domain containing 2 | 0.0469625 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0460373 |
| KYNU | kynureninase | 0.0459528 |
| RPS2 | ribosomal protein S2 | 0.0424784 |
| ENO1 | enolase 1, (alpha) | 0.0423785 |
| FNDC3A | fibronectin type III domain containing 3A | 0.041997 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0407956 |
| RPS17 | ribosomal protein S17 | 0.0392387 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0389829 |
| INHBA | inhibin, beta A | 0.0384531 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384314 |
| RPS27 | ribosomal protein S27 | 0.0383223 |
| MAP7 | microtubule-associated protein 7 | 0.0374883 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0373624 |
| RACK1 | receptor for activated C kinase 1 | 0.0368211 |
| INTS6 | integrator complex subunit 6 | 0.0349759 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0344087 |
| RPL31 | ribosomal protein L31 | 0.0342923 |
| RPL9 | ribosomal protein L9 | 0.0333271 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0332503 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0330549 |
| RAD51B | RAD51 paralog B | 0.0323091 |
| RPL37 | ribosomal protein L37 | 0.0322404 |
| XYLT1 | xylosyltransferase I | 0.0304362 |
| RPL12 | ribosomal protein L12 | 0.0292175 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0285095 |
| RPS27A | ribosomal protein S27a | 0.0281504 |
| SMAD2 | SMAD family member 2 | 0.0281037 |
| RPL11 | ribosomal protein L11 | 0.027696 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0272829 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0270451 |
| STC1 | stanniocalcin 1 | 0.0269021 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0265781 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0259825 |
| CTBP2 | C-terminal binding protein 2 | 0.0258638 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0252157 |
| DNER | delta/notch-like EGF repeat containing | 0.0250135 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0249064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0242937 |
| DENND1A | DENN/MADD domain containing 1A | 0.024113 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0239787 |
| ZNF638 | zinc finger protein 638 | 0.0237647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0234486 |
| SET | SET nuclear proto-oncogene | 0.0230764 |
| SFTPA2 | surfactant protein A2 | 0.0227379 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0224829 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0223766 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0222574 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0219035 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0218978 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0216052 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0215798 |
| OXSR1 | oxidative stress responsive 1 | 0.0215502 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0215281 |
| SVIL | supervillin | 0.0214232 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0212665 |
| RPL36A | ribosomal protein L36a | 0.0212229 |
| RPL35A | ribosomal protein L35a | 0.0212204 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0210762 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0209562 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0206105 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0202349 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201049 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0199425 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0197195 |
| CDK13 | cyclin-dependent kinase 13 | 0.0194493 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0194133 |
| RPL34 | ribosomal protein L34 | 0.0191151 |
| RORA | RAR-related orphan receptor A | 0.0189904 |
| RPS29 | ribosomal protein S29 | 0.0189332 |
| RPS24 | ribosomal protein S24 | 0.0189074 |
| RPL18 | ribosomal protein L18 | 0.0186182 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0185731 |
| IRS2 | insulin receptor substrate 2 | 0.0185164 |
| RPL4 | ribosomal protein L4 | 0.0184618 |
| CHL1 | cell adhesion molecule L1-like | 0.0184613 |
| AHNAK | AHNAK nucleoprotein | 0.018404 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.018139 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0181254 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.121609 |
| GDA | guanine deaminase | -0.118651 |
| TXNRD1 | thioredoxin reductase 1 | -0.111743 |
| TMSB10 | thymosin beta 10 | -0.0929679 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0861801 |
| ASPH | aspartate beta-hydroxylase | -0.0841929 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0814138 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0769293 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0733773 |
| PTMA | prothymosin, alpha | -0.0731863 |
| SMYD3 | SET and MYND domain containing 3 | -0.0694752 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0690702 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0673042 |
| EFNA5 | ephrin-A5 | -0.064815 |
| NRCAM | neuronal cell adhesion molecule | -0.0629645 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0623438 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0618146 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0589347 |
| FN1 | fibronectin 1 | -0.0565089 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0552114 |
| MYOF | myoferlin | -0.0549426 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0527618 |
| RTN4 | reticulon 4 | -0.052161 |
| MFF | mitochondrial fission factor | -0.051134 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0495749 |
| RTN1 | reticulon 1 | -0.0477548 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0477083 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0468194 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.045513 |
| LAMB1 | laminin, beta 1 | -0.0441324 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0433282 |
| PCBP2 | poly(rC) binding protein 2 | -0.0432251 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0431948 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0427249 |
| TBXT | T-box transcription factor T | -0.0426296 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0395867 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0393075 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.038801 |
| CENPF | centromere protein F, 350/400kDa | -0.0380467 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377528 |
| PALLD | palladin, cytoskeletal associated protein | -0.0365709 |
| CD109 | CD109 molecule | -0.0363443 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0359274 |
| POTEF | POTE ankyrin domain family, member F | -0.0358605 |
| NEK7 | NIMA-related kinase 7 | -0.0352767 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.035155 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0349612 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0326326 |
| YBX1 | Y box binding protein 1 | -0.0320214 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0313715 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0305842 |
| OSMR | oncostatin M receptor | -0.0301755 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0300454 |
| PFN1 | profilin 1 | -0.0297226 |
| FTL | ferritin, light polypeptide | -0.0290019 |
| CTSC | cathepsin C | -0.0290007 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0289882 |
| COL5A2 | collagen, type V, alpha 2 | -0.0286938 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0286143 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0284485 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0278593 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0271454 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0269216 |
| BSG | basigin (Ok blood group) | -0.0260362 |
| PTEN | phosphatase and tensin homolog | -0.0258998 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0257475 |
| EGR1 | early growth response 1 | -0.0252699 |
| S100A6 | S100 calcium binding protein A6 | -0.0252061 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0251994 |
| VMP1 | vacuole membrane protein 1 | -0.0251108 |
| ENAH | enabled homolog (Drosophila) | -0.0249789 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0244745 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0244213 |
| HLA-A | major histocompatibility complex, class I, A | -0.0242393 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0241621 |
| LDHA | lactate dehydrogenase A | -0.0241587 |
| MSN | moesin | -0.0240481 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0234759 |
| PKM | pyruvate kinase, muscle | -0.0233843 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0233165 |
| GLIS3 | GLIS family zinc finger 3 | -0.0227593 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.022624 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0226096 |
| MAP1B | microtubule-associated protein 1B | -0.0225298 |
| SRPK2 | SRSF protein kinase 2 | -0.0224327 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0224031 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0223444 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0221519 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0220768 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0220735 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0219555 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0218993 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0218928 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0218783 |
| PCBP3 | poly(rC) binding protein 3 | -0.0218354 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.0216588 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0214305 |
| TPM4 | tropomyosin 4 | -0.0213157 |
| TUBA1B | tubulin, alpha 1b | -0.021313 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0207311 |
