| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
110 genes differentially expressed following the Vilanterol_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.172907 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.17154 |
| MT2A | metallothionein 2A | 0.165539 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.140854 |
| PDE10A | phosphodiesterase 10A | 0.110493 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.108345 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.106396 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.105829 |
| RPS12 | ribosomal protein S12 | 0.102396 |
| RPL26 | ribosomal protein L26 | 0.0998116 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0968621 |
| EGFR | epidermal growth factor receptor | 0.0950796 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0918979 |
| DSPP | dentin sialophosphoprotein | 0.0866443 |
| RIGI | RNA sensor RIG-I | 0.0788896 |
| RPS6 | ribosomal protein S6 | 0.0783292 |
| FAT1 | FAT atypical cadherin 1 | 0.0774579 |
| RPS27A | ribosomal protein S27a | 0.076572 |
| GPC6 | glypican 6 | 0.0708828 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0707071 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0701881 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0681484 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0643709 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0597636 |
| SBF2 | SET binding factor 2 | 0.0561179 |
| PDLIM5 | PDZ and LIM domain 5 | 0.055299 |
| RUNX1 | runt-related transcription factor 1 | 0.0546545 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0478779 |
| RPL19 | ribosomal protein L19 | 0.0475475 |
| RPLP2 | ribosomal protein, large, P2 | 0.0466538 |
| RPS3 | ribosomal protein S3 | 0.0462327 |
| APP | amyloid beta (A4) precursor protein | 0.0457955 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0450133 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0448938 |
| RPL37A | ribosomal protein L37a | 0.0424347 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0422836 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0410536 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0385029 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0380433 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0371918 |
| RPS16 | ribosomal protein S16 | 0.0339336 |
| CDH13 | cadherin 13 | 0.0329006 |
| RORA | RAR-related orphan receptor A | 0.0326286 |
| BBX | bobby sox homolog (Drosophila) | 0.0307407 |
| RPL35A | ribosomal protein L35a | 0.0301341 |
| DST | dystonin | 0.0247552 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.022138 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0212194 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0192774 |
| PRKD3 | protein kinase D3 | 0.0162944 |
| RPL23 | ribosomal protein L23 | 0.0161063 |
| TSC22D2 | TSC22 domain family, member 2 | 0.015699 |
| PRRC2C | proline-rich coiled-coil 2C | 0.013161 |
| TXNRD1 | thioredoxin reductase 1 | 0.00892216 |
| RPLP0 | ribosomal protein, large, P0 | 0.00423876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00375747 |
| TMSB10 | thymosin beta 10 | 0.00354487 |
| AOPEP | aminopeptidase O (putative) | 8.05645E-4 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 6.23681E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.341357 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.256792 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.230507 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.182946 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.157457 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.147044 |
| MYO1E | myosin IE | -0.130479 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.128016 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.123196 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.118959 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105609 |
| INTS6 | integrator complex subunit 6 | -0.102185 |
| LDHA | lactate dehydrogenase A | -0.102052 |
| JMJD1C | jumonji domain containing 1C | -0.0946577 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0931348 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0866468 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0863071 |
| FN1 | fibronectin 1 | -0.0858069 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.084519 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.082296 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0822031 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0803291 |
| PGK1 | phosphoglycerate kinase 1 | -0.0761195 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0721302 |
| PARD3 | par-3 family cell polarity regulator | -0.0688915 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0594743 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0586202 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0582873 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0494457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0473663 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0386391 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0384406 |
| VCL | vinculin | -0.0331755 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0291869 |
| IGF2 | insulin-like growth factor 2 | -0.0290951 |
| PTMA | prothymosin, alpha | -0.0289338 |
| ASPH | aspartate beta-hydroxylase | -0.0268059 |
| ACTG1 | actin gamma 1 | -0.0266524 |
| EFNA5 | ephrin-A5 | -0.0238157 |
| GNAS | GNAS complex locus | -0.0230087 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0218722 |
| ATXN1 | ataxin 1 | -0.0179719 |
| TCF12 | transcription factor 12 | -0.0163836 |
| NDRG1 | N-myc downstream regulated 1 | -0.0157791 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0148721 |
| FTL | ferritin, light polypeptide | -0.00902668 |
| POTEF | POTE ankyrin domain family, member F | -0.008669 |
| MORF4L2 | mortality factor 4 like 2 | -0.00861863 |
| GPHN | gephyrin | -0.00454512 |
| RPS8 | ribosomal protein S8 | -0.00361709 |
| SMYD3 | SET and MYND domain containing 3 | -0.00335009 |
