| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.226797 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.141531 |
| CADM2 | cell adhesion molecule 2 | 0.122838 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0838726 |
| PCDH9 | protocadherin 9 | 0.0778943 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0773252 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.062123 |
| ITGAV | integrin, alpha V | 0.0609791 |
| NTM | neurotrimin | 0.0573917 |
| COL3A1 | collagen, type III, alpha 1 | 0.0569105 |
| RPS6 | ribosomal protein S6 | 0.0555187 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0554325 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0536584 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0533024 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0516165 |
| RPS2 | ribosomal protein S2 | 0.045529 |
| RPS8 | ribosomal protein S8 | 0.045269 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0438279 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0436399 |
| LRRC4C | leucine rich repeat containing 4C | 0.0426707 |
| MEIS2 | Meis homeobox 2 | 0.0410587 |
| ENO1 | enolase 1, (alpha) | 0.0407766 |
| RPL35A | ribosomal protein L35a | 0.0396214 |
| RPS3 | ribosomal protein S3 | 0.0391793 |
| PRKD1 | protein kinase D1 | 0.0390741 |
| SMYD3 | SET and MYND domain containing 3 | 0.0388881 |
| PGK1 | phosphoglycerate kinase 1 | 0.038858 |
| CDH19 | cadherin 19, type 2 | 0.038663 |
| H1-0 | H1.0 linker histone | 0.0382678 |
| RPL26 | ribosomal protein L26 | 0.0374433 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0369942 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0365863 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0361874 |
| BPTF | bromodomain PHD finger transcription factor | 0.0351594 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0349808 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0345043 |
| PHIP | pleckstrin homology domain interacting protein | 0.03352 |
| SNX6 | sorting nexin 6 | 0.0307376 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0302842 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0297921 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0294828 |
| NF1 | neurofibromin 1 | 0.0290778 |
| RPS16 | ribosomal protein S16 | 0.028752 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0278974 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0278478 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0274881 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0270717 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.026727 |
| NCOR1 | nuclear receptor corepressor 1 | 0.026646 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0264877 |
| USP25 | ubiquitin specific peptidase 25 | 0.0263969 |
| NBEA | neurobeachin | 0.026086 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0253265 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0252183 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0250113 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0249415 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0248887 |
| FBXO17 | F-box protein 17 | 0.0246652 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0246513 |
| COL5A2 | collagen, type V, alpha 2 | 0.0244946 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0244543 |
| RCOR1 | REST corepressor 1 | 0.024191 |
| HMCN1 | hemicentin 1 | 0.0239708 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0238683 |
| CEP350 | centrosomal protein 350kDa | 0.0237852 |
| RPS25 | ribosomal protein S25 | 0.0235183 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0233132 |
| THOC2 | THO complex 2 | 0.0232125 |
| COL1A2 | collagen, type I, alpha 2 | 0.0227617 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0226746 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0222155 |
| TRIM2 | tripartite motif containing 2 | 0.0219691 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0218896 |
| SERF2 | small EDRK-rich factor 2 | 0.0218761 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0217468 |
| DPYD | dihydropyrimidine dehydrogenase | 0.021507 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0214342 |
| CENPP | centromere protein P | 0.0210258 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0210011 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0209624 |
| WWOX | WW domain containing oxidoreductase | 0.020859 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0205225 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0204645 |
| TLK1 | tousled-like kinase 1 | 0.0203966 |
| R3HDM1 | R3H domain containing 1 | 0.0201249 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0201243 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0200021 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0200011 |
| RPS17 | ribosomal protein S17 | 0.0198883 |
| DRC8 | dynein regulatory complex subunit 8 | 0.0196741 |
| TMF1 | TATA element modulatory factor 1 | 0.0196613 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0196255 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0194952 |
| USP1 | ubiquitin specific peptidase 1 | 0.0194226 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0192445 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0191558 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0191507 |
| FOXP2 | forkhead box P2 | 0.0191245 |
| FBXO27 | F-box protein 27 | 0.0190637 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0189688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | -0.107427 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0906978 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0791264 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0772777 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0734244 |
| VIM | vimentin | -0.062868 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0625505 |
| ZNF292 | zinc finger protein 292 | -0.0583135 |
| POTEF | POTE ankyrin domain family, member F | -0.0565172 |
| SPAG9 | sperm associated antigen 9 | -0.056214 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0507327 |
| QKI | QKI, KH domain containing, RNA binding | -0.0503193 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0494827 |
| MTF2 | metal response element binding transcription factor 2 | -0.0484917 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0464188 |
| WDR43 | WD repeat domain 43 | -0.0463919 |
| USP3 | ubiquitin specific peptidase 3 | -0.0457798 |
| EMP1 | epithelial membrane protein 1 | -0.0431418 |
| PCBP2 | poly(rC) binding protein 2 | -0.0431075 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0413274 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0412852 |
| PFN1 | profilin 1 | -0.0402718 |
| SYT1 | synaptotagmin I | -0.0397207 |
| YBX1 | Y box binding protein 1 | -0.0389067 |
| SRP54 | signal recognition particle 54kDa | -0.0386186 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.038125 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0380234 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0366577 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0361655 |
| APP | amyloid beta (A4) precursor protein | -0.0359999 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0359883 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0359529 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0359334 |
| RTN4 | reticulon 4 | -0.0355801 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0355284 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0354694 |
| MPG | N-methylpurine-DNA glycosylase | -0.0353509 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0351363 |
| ANXA2 | annexin A2 | -0.0334398 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0333236 |
| PTMA | prothymosin, alpha | -0.0331854 |
| NOP58 | NOP58 ribonucleoprotein | -0.0329474 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0327459 |
| HDAC9 | histone deacetylase 9 | -0.0326228 |
| FBXO11 | F-box protein 11 | -0.0324303 |
| RHOH | ras homolog family member H | -0.032405 |
| ENAH | enabled homolog (Drosophila) | -0.0322447 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0311404 |
| HBS1L | HBS1-like translational GTPase | -0.0309619 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0308196 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0306841 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0306831 |
| DST | dystonin | -0.030589 |
| TMSB4X | thymosin beta 4, X-linked | -0.0303761 |
| CCN2 | cellular communication network factor 2 | -0.0302663 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0298889 |
| RHEB | Ras homolog enriched in brain | -0.0296854 |
| HMGB1 | high mobility group box 1 | -0.0296773 |
| SHROOM3 | shroom family member 3 | -0.0295471 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0294613 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | -0.0293841 |
| ZNF207 | zinc finger protein 207 | -0.0289019 |
| PRR16 | proline rich 16 | -0.0288023 |
| THBS1 | thrombospondin 1 | -0.0287796 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0285852 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0284768 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0284722 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0284179 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0279987 |
| NUP58 | nucleoporin 58 | -0.0278487 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.027588 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0274968 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0273754 |
| USP53 | ubiquitin specific peptidase 53 | -0.0271546 |
| EVI5 | ecotropic viral integration site 5 | -0.0269158 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0266345 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0264472 |
| NRG1 | neuregulin 1 | -0.0263424 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0262345 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0259949 |
| CDC73 | cell division cycle 73 | -0.0259066 |
| DSTN | destrin (actin depolymerizing factor) | -0.0258502 |
| TMEM64 | transmembrane protein 64 | -0.025824 |
| MED13L | mediator complex subunit 13-like | -0.0256208 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0252494 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0252218 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.0249508 |
| METAP2 | methionyl aminopeptidase 2 | -0.0248464 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0248303 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0246648 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245969 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0244357 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0239449 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0238947 |
| CENPF | centromere protein F, 350/400kDa | -0.0237552 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0236308 |
| GNAS | GNAS complex locus | -0.0235697 |
| RBM33 | RNA binding motif protein 33 | -0.0235033 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0233406 |
| ZNF217 | zinc finger protein 217 | -0.0230154 |
