| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.161039 |
| RPS6 | ribosomal protein S6 | 0.0726358 |
| ZNF608 | zinc finger protein 608 | 0.0674972 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0633658 |
| ANXA1 | annexin A1 | 0.0501542 |
| DSCAM | Down syndrome cell adhesion molecule | 0.048253 |
| RPS12 | ribosomal protein S12 | 0.0482235 |
| HDAC9 | histone deacetylase 9 | 0.0478066 |
| RPS8 | ribosomal protein S8 | 0.0465792 |
| RPS3 | ribosomal protein S3 | 0.0441057 |
| PDGFC | platelet derived growth factor C | 0.0432566 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0406955 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0402429 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0396195 |
| RPL31 | ribosomal protein L31 | 0.039483 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0390424 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0387558 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0357747 |
| EXT1 | exostosin glycosyltransferase 1 | 0.033017 |
| ECT2 | epithelial cell transforming 2 | 0.0317521 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0311151 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0307578 |
| RPS2 | ribosomal protein S2 | 0.0302522 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0298984 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0284867 |
| RPL23 | ribosomal protein L23 | 0.0283171 |
| EZR | ezrin | 0.0281171 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0280467 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0273103 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0269138 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0263975 |
| RPL26 | ribosomal protein L26 | 0.0261291 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0261291 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0260037 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0258015 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0248688 |
| RPL18 | ribosomal protein L18 | 0.0247475 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0245817 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0240283 |
| SLMAP | sarcolemma associated protein | 0.023824 |
| SON | SON DNA binding protein | 0.0236061 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0234828 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0233872 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0232539 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0231806 |
| PCM1 | pericentriolar material 1 | 0.0231312 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0228209 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0227855 |
| JUN | jun proto-oncogene | 0.0227253 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0219778 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0218987 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0218888 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0214765 |
| TMEM65 | transmembrane protein 65 | 0.0214511 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0211875 |
| RPL36 | ribosomal protein L36 | 0.0211014 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0209855 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0207124 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0205406 |
| SNX14 | sorting nexin 14 | 0.0204083 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0202771 |
| CREBBP | CREB binding protein | 0.0202117 |
| PLPP3 | phospholipid phosphatase 3 | 0.020143 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0199429 |
| MED13 | mediator complex subunit 13 | 0.019866 |
| OGA | O-GlcNAcase | 0.0198584 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0198409 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0198074 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0197242 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0196613 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0196508 |
| GOLGB1 | golgin B1 | 0.0194361 |
| TXNIP | thioredoxin interacting protein | 0.0193087 |
| USP47 | ubiquitin specific peptidase 47 | 0.0191098 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0190676 |
| FN1 | fibronectin 1 | 0.0190149 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0188463 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0187175 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0186864 |
| PRDM2 | PR domain containing 2, with ZNF domain | 0.0183755 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.018357 |
| YLPM1 | YLP motif containing 1 | 0.0182705 |
| RPL7 | ribosomal protein L7 | 0.0182069 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0181211 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0180633 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.0180627 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.018059 |
| SPAG9 | sperm associated antigen 9 | 0.0179839 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0179809 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0178726 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0177265 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0176771 |
| RLF | rearranged L-myc fusion | 0.0175902 |
| PAPOLA | poly(A) polymerase alpha | 0.0175272 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.017441 |
| RACK1 | receptor for activated C kinase 1 | 0.0173239 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.0172989 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.017234 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0172007 |
| TRIM24 | tripartite motif containing 24 | 0.0171856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.239546 |
| PKM | pyruvate kinase, muscle | -0.119506 |
| TMSB4X | thymosin beta 4, X-linked | -0.105419 |
| BMP10 | bone morphogenetic protein 10 | -0.0925293 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0911586 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0855213 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0843044 |
| VCL | vinculin | -0.0804373 |
| AHNAK | AHNAK nucleoprotein | -0.0683611 |
| NBEA | neurobeachin | -0.0678162 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0672022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0603702 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0599058 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0539 |
| POTEF | POTE ankyrin domain family, member F | -0.0528925 |
| FHIT | fragile histidine triad | -0.0520822 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0518761 |
| S100A4 | S100 calcium binding protein A4 | -0.051396 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0484866 |
| FOXP1 | forkhead box P1 | -0.047983 |
| LDHA | lactate dehydrogenase A | -0.0478214 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0478046 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0459461 |
| PYGB | phosphorylase, glycogen; brain | -0.0441723 |
| NAV2 | neuron navigator 2 | -0.0424764 |
| DENND1A | DENN/MADD domain containing 1A | -0.0415776 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414788 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.040637 |
| TPM4 | tropomyosin 4 | -0.0402532 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0402052 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0399234 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0398767 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0380703 |
| DSTN | destrin (actin depolymerizing factor) | -0.0376836 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0373668 |
| RAD51B | RAD51 paralog B | -0.0371922 |
| DUSP4 | dual specificity phosphatase 4 | -0.0371764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0358269 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0357276 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0356084 |
| TXNRD1 | thioredoxin reductase 1 | -0.03531 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.035038 |
| CENPF | centromere protein F, 350/400kDa | -0.0335247 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0334818 |
| NFIA | nuclear factor I/A | -0.0329327 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.032559 |
| NEBL | nebulette | -0.0324372 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0324075 |
| EXOC4 | exocyst complex component 4 | -0.0317155 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0316762 |
| ANLN | anillin, actin binding protein | -0.0316422 |
| SMYD3 | SET and MYND domain containing 3 | -0.030422 |
| DIAPH3 | diaphanous-related formin 3 | -0.0301201 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0297379 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.028458 |
| GLI2 | GLI family zinc finger 2 | -0.0283261 |
| NMD3 | NMD3 ribosome export adaptor | -0.027608 |
| CD47 | CD47 molecule | -0.0274877 |
| PLXNA2 | plexin A2 | -0.0271639 |
| GPHN | gephyrin | -0.0270332 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0269136 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0266444 |
| RPLP0 | ribosomal protein, large, P0 | -0.0266169 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0262254 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0260355 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0258801 |
| PTMS | parathymosin | -0.0258396 |
| MATR3 | matrin 3 | -0.0256145 |
| MACROD2 | MACRO domain containing 2 | -0.0255983 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0255302 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0252285 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0250758 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0243584 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0239949 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0238753 |
| DIAPH2 | diaphanous-related formin 2 | -0.0237546 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0235294 |
| CCNL1 | cyclin L1 | -0.0235077 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0234975 |
| RPL5 | ribosomal protein L5 | -0.0234419 |
| RYR2 | ryanodine receptor 2 (cardiac) | -0.0232699 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0231412 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0230993 |
| PDE7B | phosphodiesterase 7B | -0.0229817 |
| MSI2 | musashi RNA-binding protein 2 | -0.0229776 |
| TOB1 | transducer of ERBB2, 1 | -0.0229354 |
| LOXL3 | lysyl oxidase-like 3 | -0.022868 |
| TPI1 | triosephosphate isomerase 1 | -0.0227165 |
| SMIM44 | small integral membrane protein 44 | -0.0227077 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0224833 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0224691 |
| PARD3 | par-3 family cell polarity regulator | -0.0222578 |
| RPS24 | ribosomal protein S24 | -0.0221618 |
| RTN4 | reticulon 4 | -0.0218719 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0218716 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0218667 |
| RIGI | RNA sensor RIG-I | -0.0217909 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0213781 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0208904 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0207903 |
