| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vilanterol_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143662 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0820382 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0711528 |
| STC1 | stanniocalcin 1 | 0.069977 |
| MT2A | metallothionein 2A | 0.0680468 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0622729 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0563298 |
| KYNU | kynureninase | 0.0520115 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0482804 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0467953 |
| HDAC9 | histone deacetylase 9 | 0.0455697 |
| RPS12 | ribosomal protein S12 | 0.044533 |
| ENO1 | enolase 1, (alpha) | 0.0421012 |
| SQSTM1 | sequestosome 1 | 0.0390257 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.035483 |
| RPS6 | ribosomal protein S6 | 0.0336079 |
| HMGA2 | high mobility group AT-hook 2 | 0.0335312 |
| RND3 | Rho family GTPase 3 | 0.0321634 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0320752 |
| BPTF | bromodomain PHD finger transcription factor | 0.0310037 |
| CTSB | cathepsin B | 0.0307533 |
| HLA-B | major histocompatibility complex, class I, B | 0.0293068 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.029172 |
| BICC1 | BicC family RNA binding protein 1 | 0.0290458 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.029037 |
| RPL37A | ribosomal protein L37a | 0.0289301 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0275852 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.026899 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0266099 |
| MT1X | metallothionein 1X | 0.0258091 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0256892 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0256123 |
| INHBA | inhibin, beta A | 0.0255688 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0255109 |
| ARFGEF3 | ARFGEF family member 3 | 0.0246788 |
| RPS8 | ribosomal protein S8 | 0.0241672 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229598 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0227838 |
| DUSP5 | dual specificity phosphatase 5 | 0.0223766 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0219623 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.021938 |
| TUT7 | terminal uridylyl transferase 7 | 0.0216904 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215665 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0215106 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0214235 |
| RPL23 | ribosomal protein L23 | 0.0206009 |
| RPL26 | ribosomal protein L26 | 0.0205808 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0203897 |
| RPS3 | ribosomal protein S3 | 0.0203599 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0201627 |
| INTS6 | integrator complex subunit 6 | 0.0199517 |
| ASPH | aspartate beta-hydroxylase | 0.0199478 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0198917 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0191402 |
| RPS17 | ribosomal protein S17 | 0.0191267 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0187232 |
| GPC6 | glypican 6 | 0.0183956 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0181782 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0181021 |
| VCAN | versican | 0.0179263 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0177435 |
| EFNA5 | ephrin-A5 | 0.017728 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0176319 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0176111 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0171371 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0169632 |
| JMJD1C | jumonji domain containing 1C | 0.0168536 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0165803 |
| PMP22 | peripheral myelin protein 22 | 0.0164092 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0162685 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0161903 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.016108 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0158265 |
| SYAP1 | synapse associated protein 1 | 0.0157105 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0156616 |
| NDRG1 | N-myc downstream regulated 1 | 0.015649 |
| PHF3 | PHD finger protein 3 | 0.0153571 |
| MYO9A | myosin IXA | 0.0152644 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.015223 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0151959 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.015156 |
| GOLGB1 | golgin B1 | 0.0150134 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0150071 |
| RPL37 | ribosomal protein L37 | 0.0149033 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0148702 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0147584 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0146178 |
| TGM2 | transglutaminase 2 | 0.0145724 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0144758 |
| INSR | insulin receptor | 0.0144651 |
| PCBP3 | poly(rC) binding protein 3 | 0.0143037 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0142504 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0140021 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0136644 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0135724 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0133556 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0133157 |
| SON | SON DNA binding protein | 0.0130461 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0128498 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0128023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.15067 |
| FRMD4A | FERM domain containing 4A | -0.140586 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.126696 |
| CADM1 | cell adhesion molecule 1 | -0.115907 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.109622 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0855142 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0683244 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0576161 |
| QKI | QKI, KH domain containing, RNA binding | -0.0574242 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0560138 |
| PDE10A | phosphodiesterase 10A | -0.0558102 |
| ATP13A3 | ATPase type 13A3 | -0.0514016 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0455106 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0442828 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0438877 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.040551 |
| TAPBP | TAP binding protein (tapasin) | -0.0397257 |
| RBM39 | RNA binding motif protein 39 | -0.0369491 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0363434 |
| YBX1 | Y box binding protein 1 | -0.0356714 |
| DST | dystonin | -0.0356216 |
| FNDC3B | fibronectin type III domain containing 3B | -0.035358 |
| VEGFA | vascular endothelial growth factor A | -0.0351567 |
| PCBP2 | poly(rC) binding protein 2 | -0.0350063 |
| ZNF292 | zinc finger protein 292 | -0.0337538 |
| THBS1 | thrombospondin 1 | -0.0335379 |
| SPAG9 | sperm associated antigen 9 | -0.0334473 |
| GOLGA4 | golgin A4 | -0.032929 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0325209 |
| HELZ | helicase with zinc finger | -0.0324166 |
| CDH13 | cadherin 13 | -0.0310412 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0309658 |
| PTMA | prothymosin, alpha | -0.0305904 |
| TENM2 | teneurin transmembrane protein 2 | -0.0304445 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0299584 |
| COL6A3 | collagen, type VI, alpha 3 | -0.029545 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0294505 |
| TNS3 | tensin 3 | -0.0291205 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0288959 |
| EGR1 | early growth response 1 | -0.0286892 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0283359 |
| WTAP | Wilms tumor 1 associated protein | -0.0280293 |
| CCNL1 | cyclin L1 | -0.0276727 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0274977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274164 |
| COL1A2 | collagen, type I, alpha 2 | -0.0273174 |
| DIAPH2 | diaphanous-related formin 2 | -0.0269703 |
| POTEF | POTE ankyrin domain family, member F | -0.0268658 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0267674 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0266545 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.026086 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0260008 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0257337 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0256242 |
| SBF2 | SET binding factor 2 | -0.025336 |
| TMEM123 | transmembrane protein 123 | -0.0252756 |
| TPM4 | tropomyosin 4 | -0.0248102 |
| TPM1 | tropomyosin 1 (alpha) | -0.024548 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0245361 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0245186 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0241379 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0240674 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0234247 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0234048 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0232298 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0231425 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.023027 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.022912 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0228755 |
| MATR3 | matrin 3 | -0.0228524 |
| CTSD | cathepsin D | -0.0227815 |
| TFG | TRK-fused gene | -0.0226999 |
| PGK1 | phosphoglycerate kinase 1 | -0.0226926 |
| RLF | rearranged L-myc fusion | -0.0226523 |
| TMSB10 | thymosin beta 10 | -0.0225178 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0224034 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0222728 |
| ANLN | anillin, actin binding protein | -0.022038 |
| FLNA | filamin A, alpha | -0.0219719 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.021783 |
| ARF4 | ADP-ribosylation factor 4 | -0.0215727 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0214513 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.021296 |
| RTN4 | reticulon 4 | -0.0212701 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0212115 |
| ANXA2 | annexin A2 | -0.0212037 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0211984 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0211484 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0210971 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0209811 |
| AFDN | afadin, adherens junction formation factor | -0.0209434 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0206073 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0205265 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0203425 |
| BNC2 | basonuclin 2 | -0.0201886 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0201315 |
| COL1A1 | collagen, type I, alpha 1 | -0.0199176 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0199021 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0197776 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0194585 |