| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vilanterol perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vilanterol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.207309 |
| SQSTM1 | sequestosome 1 | 0.106366 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0954452 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0896798 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0838933 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0795639 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0784668 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0769984 |
| ASPH | aspartate beta-hydroxylase | 0.0749024 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0596017 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0574849 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.053909 |
| TPR | translocated promoter region, nuclear basket protein | 0.053776 |
| ENO1 | enolase 1, (alpha) | 0.0532946 |
| VCL | vinculin | 0.0527638 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0507156 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0500906 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0495539 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0473023 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0472395 |
| ITGA1 | integrin, alpha 1 | 0.0461574 |
| HMGA2 | high mobility group AT-hook 2 | 0.0455802 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.044233 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0436806 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0434229 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0427602 |
| INTS6 | integrator complex subunit 6 | 0.0425906 |
| AEBP2 | AE binding protein 2 | 0.0422981 |
| GPATCH2L | G patch domain containing 2-like | 0.0399927 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0376555 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0368021 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0356342 |
| RAI14 | retinoic acid induced 14 | 0.0353249 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0349088 |
| DUSP6 | dual specificity phosphatase 6 | 0.0345528 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0336087 |
| STC2 | stanniocalcin 2 | 0.0334339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0330004 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0322979 |
| NTN4 | netrin 4 | 0.0320504 |
| CDK13 | cyclin-dependent kinase 13 | 0.0308429 |
| RAB10 | RAB10, member RAS oncogene family | 0.0308385 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0307179 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0305194 |
| TMEM156 | transmembrane protein 156 | 0.0304197 |
| RPS12 | ribosomal protein S12 | 0.030413 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.02996 |
| FNIP1 | folliculin interacting protein 1 | 0.0296517 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0285941 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.028581 |
| IRS2 | insulin receptor substrate 2 | 0.0281722 |
| CD109 | CD109 molecule | 0.0281535 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0281473 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0281304 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0280208 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0279699 |
| ATF6 | activating transcription factor 6 | 0.0273326 |
| GLUL | glutamate-ammonia ligase | 0.0271465 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0270224 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0268475 |
| UBAP2 | ubiquitin associated protein 2 | 0.0267777 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0264078 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0263828 |
| EREG | epiregulin | 0.026366 |
| KLHL5 | kelch-like family member 5 | 0.0262493 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0262133 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0261355 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0254351 |
| BPTF | bromodomain PHD finger transcription factor | 0.0251339 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0250923 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0248518 |
| PCBP3 | poly(rC) binding protein 3 | 0.0248389 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0247985 |
| SFTPA2 | surfactant protein A2 | 0.0246915 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0245724 |
| MYO1E | myosin IE | 0.0245622 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0245476 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0244293 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.024313 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0242462 |
| PALLD | palladin, cytoskeletal associated protein | 0.0240494 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0240346 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0238837 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0238427 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0238286 |
| UBN2 | ubinuclein 2 | 0.0237644 |
| USP34 | ubiquitin specific peptidase 34 | 0.0237349 |
| FN1 | fibronectin 1 | 0.023498 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0232322 |
| PLIN2 | perilipin 2 | 0.0229553 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0229342 |
| RCOR1 | REST corepressor 1 | 0.0228097 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0227294 |
| SON | SON DNA binding protein | 0.022688 |
| CCDC138 | coiled-coil domain containing 138 | 0.0226289 |
| FERMT2 | fermitin family member 2 | 0.0222442 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0221694 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.022098 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0219601 |
| CTBP2 | C-terminal binding protein 2 | 0.0217849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.107228 |
| TMSB10 | thymosin beta 10 | -0.0938503 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0816916 |
| MT2A | metallothionein 2A | -0.0800312 |
| S100A6 | S100 calcium binding protein A6 | -0.0630308 |
| VIM | vimentin | -0.0618312 |
| PTMA | prothymosin, alpha | -0.0601166 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0582704 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0576269 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0513839 |
| RPLP1 | ribosomal protein, large, P1 | -0.0468407 |
| FTL | ferritin, light polypeptide | -0.0455444 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0422141 |
| SMOX | spermine oxidase | -0.0401888 |
| OSMR | oncostatin M receptor | -0.0400401 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0397492 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0340505 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0335703 |
| CDC27 | cell division cycle 27 | -0.0296468 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0287518 |
| RTN4 | reticulon 4 | -0.028218 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0279181 |
| PKM | pyruvate kinase, muscle | -0.0277492 |
| CDCP1 | CUB domain containing protein 1 | -0.0271798 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0262733 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.026241 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0261454 |
| CD44 | CD44 molecule (Indian blood group) | -0.026086 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0259693 |
| VEGFA | vascular endothelial growth factor A | -0.0256237 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0247728 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0245475 |
| FOSL1 | FOS-like antigen 1 | -0.0245451 |
| TMEM131 | transmembrane protein 131 | -0.0243432 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0236742 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0233215 |
| ITGB5 | integrin, beta 5 | -0.0232619 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.023251 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0231589 |
| TMEM165 | transmembrane protein 165 | -0.0229618 |
| MAP1B | microtubule-associated protein 1B | -0.0229532 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0224188 |
| NUP58 | nucleoporin 58 | -0.0222751 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0222355 |
| HMGA1 | high mobility group AT-hook 1 | -0.0217565 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0215802 |
| SERF2 | small EDRK-rich factor 2 | -0.0215575 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0213987 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0213498 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0211417 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0210092 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0210082 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0205651 |
| SRPK2 | SRSF protein kinase 2 | -0.0205414 |
| PFN1 | profilin 1 | -0.0205252 |
| NRG1 | neuregulin 1 | -0.0204105 |
| FOXP1 | forkhead box P1 | -0.0203482 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0202439 |
| RBM39 | RNA binding motif protein 39 | -0.020197 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0197698 |
| DENND4C | DENN/MADD domain containing 4C | -0.0197638 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0197595 |
| ZNF292 | zinc finger protein 292 | -0.0196808 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0196236 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0195167 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0194987 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0194419 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0193425 |
| RPS19 | ribosomal protein S19 | -0.019155 |
| YBX1 | Y box binding protein 1 | -0.0191142 |
| PGK1 | phosphoglycerate kinase 1 | -0.019112 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0185735 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.0182987 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0181223 |
| COG5 | component of oligomeric golgi complex 5 | -0.0180751 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0179739 |
| CST3 | cystatin C | -0.0179106 |
| SUCO | SUN domain containing ossification factor | -0.0178573 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0177791 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0177785 |
| RPS20 | ribosomal protein S20 | -0.0177482 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0176028 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0175965 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0175092 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0174896 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0174052 |
| IL6 | interleukin 6 | -0.0171451 |
| RHEB | Ras homolog enriched in brain | -0.0171223 |
| CCNL1 | cyclin L1 | -0.0169626 |
| FAM3C | family with sequence similarity 3, member C | -0.0169341 |
| SMYD3 | SET and MYND domain containing 3 | -0.0169283 |
| FAM168B | family with sequence similarity 168, member B | -0.0169084 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0169064 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0166837 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0166283 |
| CENPF | centromere protein F, 350/400kDa | -0.0166166 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.016601 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0165536 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0165335 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0164384 |
