| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.119811 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.113238 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.110039 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0945978 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0770026 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0683782 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0676001 |
| HDAC9 | histone deacetylase 9 | 0.0602414 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0599066 |
| FN1 | fibronectin 1 | 0.0550272 |
| NAV2 | neuron navigator 2 | 0.0545567 |
| SP100 | SP100 nuclear antigen | 0.0524435 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0510662 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0504921 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0499425 |
| B2M | beta-2-microglobulin | 0.0487857 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0470569 |
| S100A10 | S100 calcium binding protein A10 | 0.0451975 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0448616 |
| CSTB | cystatin B (stefin B) | 0.0446881 |
| SUCNR1 | succinate receptor 1 | 0.0418475 |
| RIGI | RNA sensor RIG-I | 0.04178 |
| MX2 | MX dynamin-like GTPase 2 | 0.0396314 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0387085 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0386365 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0384374 |
| LDHA | lactate dehydrogenase A | 0.0383779 |
| VIM | vimentin | 0.0377585 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0376815 |
| VCL | vinculin | 0.0376012 |
| SQSTM1 | sequestosome 1 | 0.0371725 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.037104 |
| SEPTIN7 | septin 7 | 0.0356894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345966 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0335166 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0322983 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0322153 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.031485 |
| OGA | O-GlcNAcase | 0.0313754 |
| MSI2 | musashi RNA-binding protein 2 | 0.0308655 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0306692 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303635 |
| CANX | calnexin | 0.0300438 |
| MEIS2 | Meis homeobox 2 | 0.0295535 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0294808 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0290477 |
| PRELID2 | PRELI domain containing 2 | 0.0286732 |
| PKM | pyruvate kinase, muscle | 0.0283466 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279453 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0278758 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.026047 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0259683 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0257837 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0257446 |
| STC1 | stanniocalcin 1 | 0.0254022 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0247773 |
| XPO1 | exportin 1 | 0.0244792 |
| TUFT1 | tuftelin 1 | 0.0244786 |
| RUNX1 | runt-related transcription factor 1 | 0.024452 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0244331 |
| CALR | calreticulin | 0.024312 |
| TPM3 | tropomyosin 3 | 0.0241627 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0239937 |
| ZNF292 | zinc finger protein 292 | 0.023861 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0237924 |
| JMJD1C | jumonji domain containing 1C | 0.0237125 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0236266 |
| NAV1 | neuron navigator 1 | 0.0235653 |
| DST | dystonin | 0.0232084 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227975 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0227946 |
| ANXA2 | annexin A2 | 0.0227931 |
| CD109 | CD109 molecule | 0.0222728 |
| RNF213 | ring finger protein 213 | 0.0220773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0216561 |
| HELZ | helicase with zinc finger | 0.021624 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0213021 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0211544 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0208282 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0205299 |
| PRSS23 | protease, serine, 23 | 0.0202795 |
| PRKCE | protein kinase C, epsilon | 0.0201846 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0200619 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0199457 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0198333 |
| CENPF | centromere protein F, 350/400kDa | 0.0197284 |
| GOLGA4 | golgin A4 | 0.0197128 |
| MYOF | myoferlin | 0.0196654 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0195991 |
| LRRC17 | leucine rich repeat containing 17 | 0.0194842 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0194577 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0193896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0193439 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0193039 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0189795 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0189227 |
| PMP22 | peripheral myelin protein 22 | 0.0186124 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0185429 |
| MMP12 | matrix metallopeptidase 12 | 0.0185011 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.018468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.238363 |
| TMSB10 | thymosin beta 10 | -0.16639 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.164679 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0992387 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.095672 |
| CDH13 | cadherin 13 | -0.0812563 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0765465 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0749329 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0730819 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0689877 |
| PODXL | podocalyxin-like | -0.0689428 |
| NDRG1 | N-myc downstream regulated 1 | -0.0611314 |
| FLNB | filamin B, beta | -0.0478695 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0441102 |
| OXTR | oxytocin receptor | -0.0413086 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0388953 |
| MT2A | metallothionein 2A | -0.0373128 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.037039 |
| LOX | lysyl oxidase | -0.0367 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0366853 |
| LOXL2 | lysyl oxidase-like 2 | -0.0358655 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0345178 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0317875 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0317587 |
| PLAT | plasminogen activator, tissue | -0.031705 |
| FBN1 | fibrillin 1 | -0.0292959 |
| TXNRD1 | thioredoxin reductase 1 | -0.0292208 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0280043 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0277992 |
| AHNAK | AHNAK nucleoprotein | -0.0271731 |
| ACTG1 | actin gamma 1 | -0.0269426 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0255552 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0254163 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0249476 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.024679 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0237045 |
| LMO7 | LIM domain 7 | -0.0229591 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0224724 |
| KRT81 | keratin 81, type II | -0.0223753 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.022063 |
| KLF6 | Kruppel-like factor 6 | -0.0218702 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0213245 |
| CCND1 | cyclin D1 | -0.0211198 |
| PFN1 | profilin 1 | -0.0205203 |
| COL3A1 | collagen, type III, alpha 1 | -0.0204907 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0200518 |
| THBS2 | thrombospondin 2 | -0.0198652 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193652 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0193332 |
| RPL23 | ribosomal protein L23 | -0.0191536 |
| MT1X | metallothionein 1X | -0.0191425 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0190776 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0186208 |
| RPL12 | ribosomal protein L12 | -0.0183734 |
| CCN2 | cellular communication network factor 2 | -0.0181864 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0181205 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.018017 |
| CAVIN1 | caveolae associated protein 1 | -0.0174801 |
| ACTN4 | actinin, alpha 4 | -0.0174166 |
| POTEF | POTE ankyrin domain family, member F | -0.0174028 |
| PLCB4 | phospholipase C, beta 4 | -0.0171474 |
| BSG | basigin (Ok blood group) | -0.0170328 |
| FMN2 | formin 2 | -0.0169141 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0167056 |
| TUBB | tubulin, beta class I | -0.0165498 |
| RPS19 | ribosomal protein S19 | -0.016517 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0163973 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0159953 |
| RPL35A | ribosomal protein L35a | -0.0159168 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0157387 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.015644 |
| MPP7 | membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) | -0.0155496 |
| RACK1 | receptor for activated C kinase 1 | -0.015534 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0155122 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0152447 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0150664 |
| ERBIN | erbb2 interacting protein | -0.0149137 |
| FTL | ferritin, light polypeptide | -0.0147086 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0146715 |
| RPL34 | ribosomal protein L34 | -0.0145462 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0145042 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0145003 |
| RRBP1 | ribosome binding protein 1 | -0.0143808 |
| RPS23 | ribosomal protein S23 | -0.0143302 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0142348 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0142226 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0142174 |
| ECM1 | extracellular matrix protein 1 | -0.0141299 |
| RPL28 | ribosomal protein L28 | -0.0139807 |
| SMIM44 | small integral membrane protein 44 | -0.0137483 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0136566 |
| RPS14 | ribosomal protein S14 | -0.0135622 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0135487 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0134419 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0133679 |
| GDI1 | GDP dissociation inhibitor 1 | -0.0133319 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.013294 |
| MYADM | myeloid-associated differentiation marker | -0.0132842 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0132549 |
| CCDC85A | coiled-coil domain containing 85A | -0.0132144 |
