| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMC4 | structural maintenance of chromosomes 4 | 0.0729545 |
| PCBP2 | poly(rC) binding protein 2 | 0.0610326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0595204 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0500024 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0497179 |
| TMEM41B | transmembrane protein 41B | 0.047405 |
| ZNF292 | zinc finger protein 292 | 0.0463573 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0454954 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0434421 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0424385 |
| VMP1 | vacuole membrane protein 1 | 0.0419146 |
| NEBL | nebulette | 0.0418813 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0410466 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0405744 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0405141 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0404438 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0399999 |
| PCM1 | pericentriolar material 1 | 0.0399772 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0395006 |
| YAP1 | Yes-associated protein 1 | 0.0380764 |
| XPO1 | exportin 1 | 0.0377407 |
| CCNL1 | cyclin L1 | 0.0375264 |
| NLGN1 | neuroligin 1 | 0.0359863 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0337959 |
| MED13L | mediator complex subunit 13-like | 0.0326925 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0325697 |
| RBM25 | RNA binding motif protein 25 | 0.0322595 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304332 |
| RRM2 | ribonucleotide reductase M2 | 0.0301662 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0295154 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0288227 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0287814 |
| SEPTIN7 | septin 7 | 0.028651 |
| NEK7 | NIMA-related kinase 7 | 0.0285437 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0284075 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0274205 |
| CCDC88A | coiled-coil domain containing 88A | 0.0274038 |
| EDN1 | endothelin 1 | 0.0272926 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.027215 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0269116 |
| WWOX | WW domain containing oxidoreductase | 0.0267571 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0267482 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0261576 |
| ZNF638 | zinc finger protein 638 | 0.0259458 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.025511 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0255092 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0254594 |
| TENM3 | teneurin transmembrane protein 3 | 0.0254405 |
| NKTR | natural killer cell triggering receptor | 0.0254092 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0254021 |
| FBXO11 | F-box protein 11 | 0.0251755 |
| EPHA6 | EPH receptor A6 | 0.0250709 |
| EDARADD | EDAR-associated death domain | 0.0249646 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.024768 |
| ECT2 | epithelial cell transforming 2 | 0.0246162 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0245024 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0233753 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0231658 |
| TBK1 | TANK-binding kinase 1 | 0.0228698 |
| TPR | translocated promoter region, nuclear basket protein | 0.0228092 |
| CPOX | coproporphyrinogen oxidase | 0.0227469 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0227239 |
| TJP1 | tight junction protein 1 | 0.0226803 |
| EXOC6B | exocyst complex component 6B | 0.0226535 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0226452 |
| RSF1 | remodeling and spacing factor 1 | 0.0226325 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.022329 |
| CIP2A | cellular inhibitor of PP2A | 0.0223042 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0222354 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0221361 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0218562 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0218196 |
| RAD51B | RAD51 paralog B | 0.0217448 |
| CENPF | centromere protein F, 350/400kDa | 0.0216397 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.021494 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0214815 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0214736 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.021437 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0214343 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0212031 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0210209 |
| PEG10 | paternally expressed 10 | 0.020832 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0204577 |
| NF1 | neurofibromin 1 | 0.0202559 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0202495 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0202413 |
| TFG | TRK-fused gene | 0.0202331 |
| TPI1 | triosephosphate isomerase 1 | 0.0201666 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0199831 |
| PTMA | prothymosin, alpha | 0.0199702 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0196409 |
| PRKCI | protein kinase C, iota | 0.019355 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.019348 |
| RBM39 | RNA binding motif protein 39 | 0.0192597 |
| FAM13B | family with sequence similarity 13, member B | 0.019081 |
| SETD5 | SET domain containing 5 | 0.0190186 |
| USP34 | ubiquitin specific peptidase 34 | 0.0186653 |
| TNPO1 | transportin 1 | 0.0186593 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0186428 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.018558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.176276 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.157499 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.150623 |
| VIM | vimentin | -0.123125 |
| YBX3 | Y box binding protein 3 | -0.120629 |
| AREG | amphiregulin | -0.10897 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0919302 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0850533 |
| HMGA2 | high mobility group AT-hook 2 | -0.0820825 |
| MMP12 | matrix metallopeptidase 12 | -0.0760612 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0745301 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0733925 |
| ANXA1 | annexin A1 | -0.0624828 |
| PRDX1 | peroxiredoxin 1 | -0.0612607 |
| RPL23 | ribosomal protein L23 | -0.0571105 |
| BCHE | butyrylcholinesterase | -0.0565422 |
| TXNRD1 | thioredoxin reductase 1 | -0.0551433 |
| RASAL2 | RAS protein activator like 2 | -0.0548314 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0528188 |
| EHBP1 | EH domain binding protein 1 | -0.050976 |
| RPL26 | ribosomal protein L26 | -0.0455287 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0447744 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0425378 |
| AHNAK | AHNAK nucleoprotein | -0.041641 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0413063 |
| EZR | ezrin | -0.0407761 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.039215 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0386885 |
| RPS12 | ribosomal protein S12 | -0.0381885 |
| ACTG1 | actin gamma 1 | -0.0379278 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0371104 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0368659 |
| CLDN1 | claudin 1 | -0.0364276 |
| RPL35A | ribosomal protein L35a | -0.0345211 |
| FTL | ferritin, light polypeptide | -0.0338507 |
| CALD1 | caldesmon 1 | -0.0335088 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0334668 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0324422 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.03243 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0321638 |
| S100A6 | S100 calcium binding protein A6 | -0.0320579 |
| RTN4 | reticulon 4 | -0.0319651 |
| EGFR | epidermal growth factor receptor | -0.031894 |
| RPL12 | ribosomal protein L12 | -0.0304259 |
| ZNF804A | zinc finger protein 804A | -0.0303572 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0290188 |
| RPS6 | ribosomal protein S6 | -0.0286694 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0283454 |
| RPS3 | ribosomal protein S3 | -0.0269676 |
| ASPH | aspartate beta-hydroxylase | -0.026648 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0256644 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0256154 |
| S100A11 | S100 calcium binding protein A11 | -0.025353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0250955 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0240059 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0236096 |
| TUBB | tubulin, beta class I | -0.023589 |
| RPL3 | ribosomal protein L3 | -0.0234071 |
| LMO7 | LIM domain 7 | -0.0232056 |
| RPS27A | ribosomal protein S27a | -0.0229753 |
| INTS6 | integrator complex subunit 6 | -0.0228583 |
| TUBA1B | tubulin, alpha 1b | -0.0223125 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0222809 |
| MAP1B | microtubule-associated protein 1B | -0.0221308 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0219933 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0208585 |
| KLF6 | Kruppel-like factor 6 | -0.0206955 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0201789 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0197456 |
| RPS8 | ribosomal protein S8 | -0.0193427 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.019284 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0191982 |
| RPL34 | ribosomal protein L34 | -0.0190032 |
| RPS17 | ribosomal protein S17 | -0.0188977 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0185245 |
| NABP1 | nucleic acid binding protein 1 | -0.0185174 |
| DST | dystonin | -0.0184603 |
| USP53 | ubiquitin specific peptidase 53 | -0.0179905 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0178823 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0176755 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0175887 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0174208 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0174019 |
| RPLP0 | ribosomal protein, large, P0 | -0.0173908 |
| RPL4 | ribosomal protein L4 | -0.0171884 |
| CUX1 | cut-like homeobox 1 | -0.0171088 |
| CDV3 | CDV3 homolog (mouse) | -0.0170959 |
| STIP1 | stress-induced phosphoprotein 1 | -0.0170637 |
| MYPN | myopalladin | -0.016963 |
| RPS14 | ribosomal protein S14 | -0.0169258 |
| RAB10 | RAB10, member RAS oncogene family | -0.0167871 |
| NHSL1 | NHS-like 1 | -0.0166646 |
| RPS24 | ribosomal protein S24 | -0.0166122 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0165011 |
| EPHA5 | EPH receptor A5 | -0.0164867 |
| RPS2 | ribosomal protein S2 | -0.0164657 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0164079 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0163102 |
| SLC39A11 | solute carrier family 39, member 11 | -0.016216 |
| RPL19 | ribosomal protein L19 | -0.0160805 |
