| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.186985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.142262 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0933354 |
| FMNL2 | formin-like 2 | 0.0811517 |
| SPAG9 | sperm associated antigen 9 | 0.0779547 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0756041 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0664499 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0661969 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0610742 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0607456 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.059636 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0567239 |
| NAV2 | neuron navigator 2 | 0.0560849 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0515393 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.051223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0505488 |
| CADM1 | cell adhesion molecule 1 | 0.050379 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0501096 |
| PAX8 | paired box 8 | 0.0498647 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0495762 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0494458 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0493486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0478762 |
| COPA | coatomer protein complex, subunit alpha | 0.0473721 |
| NDRG1 | N-myc downstream regulated 1 | 0.047143 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0470264 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0453336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0432607 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0424802 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0423102 |
| XPO1 | exportin 1 | 0.0415519 |
| INTS6 | integrator complex subunit 6 | 0.0410781 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0399742 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0399114 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0398299 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394524 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0390433 |
| PKM | pyruvate kinase, muscle | 0.0388216 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0385677 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0381568 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0378165 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0373639 |
| ANXA5 | annexin A5 | 0.0361627 |
| MSN | moesin | 0.0359789 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0358366 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0357382 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0357351 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.034579 |
| CXXC1 | CXXC finger protein 1 | 0.0345061 |
| TUBA1B | tubulin, alpha 1b | 0.0345016 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0336091 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0335844 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0331783 |
| TFG | TRK-fused gene | 0.0327016 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323337 |
| HBP1 | HMG-box transcription factor 1 | 0.0323036 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0322549 |
| UBAP2 | ubiquitin associated protein 2 | 0.0320809 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0320794 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0320407 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0320065 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.031946 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0316397 |
| SUCO | SUN domain containing ossification factor | 0.0315847 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0315308 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0313857 |
| RAB18 | RAB18, member RAS oncogene family | 0.0308654 |
| FBXO11 | F-box protein 11 | 0.030809 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.030797 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0307639 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0305761 |
| RND3 | Rho family GTPase 3 | 0.0303243 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0296089 |
| RIGI | RNA sensor RIG-I | 0.0294875 |
| SRP54 | signal recognition particle 54kDa | 0.0294063 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0293996 |
| CTBP2 | C-terminal binding protein 2 | 0.0292428 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.029218 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0290339 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0289251 |
| JAK1 | Janus kinase 1 | 0.0289059 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0288491 |
| SDCBP | syndecan binding protein (syntenin) | 0.0287073 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0286666 |
| USP53 | ubiquitin specific peptidase 53 | 0.028529 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.028275 |
| UBC | ubiquitin C | 0.0282465 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0282324 |
| PCBP2 | poly(rC) binding protein 2 | 0.0282164 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0281334 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0280222 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0280162 |
| HELZ | helicase with zinc finger | 0.0277796 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0276758 |
| HDAC9 | histone deacetylase 9 | 0.0274744 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0273963 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0272968 |
| HIP1 | huntingtin interacting protein 1 | 0.0270622 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0269894 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0269031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.138257 |
| ASPH | aspartate beta-hydroxylase | -0.137514 |
| MT2A | metallothionein 2A | -0.120187 |
| GLIS3 | GLIS family zinc finger 3 | -0.0999197 |
| VIM | vimentin | -0.0990971 |
| GPC6 | glypican 6 | -0.0943283 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0717212 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0692759 |
| TXNRD1 | thioredoxin reductase 1 | -0.0596614 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0562817 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0548776 |
| SMAD3 | SMAD family member 3 | -0.0533621 |
| LOXL2 | lysyl oxidase-like 2 | -0.0509525 |
| FAT1 | FAT atypical cadherin 1 | -0.0483879 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0452513 |
| RPL26 | ribosomal protein L26 | -0.0450962 |
| ETV6 | ets variant 6 | -0.0447247 |
| NRP1 | neuropilin 1 | -0.0440601 |
| OSMR | oncostatin M receptor | -0.0435464 |
| RPS24 | ribosomal protein S24 | -0.0433359 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0432552 |
| STK17A | serine/threonine kinase 17a | -0.0429116 |
| TGFB2 | transforming growth factor, beta 2 | -0.042859 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0425771 |
| TNS3 | tensin 3 | -0.042213 |
| RPL23 | ribosomal protein L23 | -0.0406243 |
| RRBP1 | ribosome binding protein 1 | -0.0383929 |
| RPL9 | ribosomal protein L9 | -0.0363759 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0355477 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0352636 |
| RAI14 | retinoic acid induced 14 | -0.033569 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0327401 |
| VCL | vinculin | -0.032143 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.031563 |
| RPL12 | ribosomal protein L12 | -0.0310026 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0302314 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0301807 |
| RPL31 | ribosomal protein L31 | -0.030038 |
| BICC1 | BicC family RNA binding protein 1 | -0.0300152 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0295486 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0288774 |
| TGFA | transforming growth factor, alpha | -0.0286708 |
| RPL34 | ribosomal protein L34 | -0.0285162 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0283603 |
| HLA-B | major histocompatibility complex, class I, B | -0.0282213 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0281031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0279123 |
| RPLP2 | ribosomal protein, large, P2 | -0.0276478 |
| RPS17 | ribosomal protein S17 | -0.0275284 |
| RPL35A | ribosomal protein L35a | -0.0273895 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0270846 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0267157 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0259736 |
| CDCP1 | CUB domain containing protein 1 | -0.0259471 |
| AOPEP | aminopeptidase O (putative) | -0.0252886 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0252713 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0251352 |
| TPM1 | tropomyosin 1 (alpha) | -0.0251348 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0249286 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0249108 |
| GDA | guanine deaminase | -0.0248849 |
| RPL36A | ribosomal protein L36a | -0.0247111 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0245062 |
| RPS19 | ribosomal protein S19 | -0.0244904 |
| SP3 | Sp3 transcription factor | -0.0244009 |
| RPL37A | ribosomal protein L37a | -0.0240639 |
| PTH2R | parathyroid hormone 2 receptor | -0.0240587 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.024045 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0239005 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0236443 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0235074 |
| PTGR1 | prostaglandin reductase 1 | -0.0234114 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0232359 |
| RPL37 | ribosomal protein L37 | -0.0231932 |
| PHF14 | PHD finger protein 14 | -0.0229708 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.022226 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022172 |
| CCDC146 | coiled-coil domain containing 146 | -0.0221062 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0219703 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.021786 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.021633 |
| RPS4X | ribosomal protein S4, X-linked | -0.0214922 |
| OXR1 | oxidation resistance 1 | -0.0213421 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0212504 |
| CD44 | CD44 molecule (Indian blood group) | -0.0211335 |
| RPL19 | ribosomal protein L19 | -0.0211277 |
| RPS27A | ribosomal protein S27a | -0.0209658 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -0.0209557 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0208544 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0207804 |
| SCFD2 | sec1 family domain containing 2 | -0.0207106 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0207058 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0206969 |
| PTMA | prothymosin, alpha | -0.0206723 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0204247 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0203703 |
| CP | ceruloplasmin (ferroxidase) | -0.0202755 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0202222 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0200883 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0200702 |
