| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.0738366 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0670125 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0658565 |
| INTS6 | integrator complex subunit 6 | 0.0639788 |
| CEP250 | centrosomal protein 250kDa | 0.063193 |
| DTNA | dystrobrevin, alpha | 0.0594373 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0540924 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.051511 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0504376 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0487668 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0470531 |
| VMP1 | vacuole membrane protein 1 | 0.0428853 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0415273 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0406191 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0401079 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0390296 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0382001 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0350583 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0342485 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0338552 |
| VCL | vinculin | 0.0337435 |
| CDK12 | cyclin-dependent kinase 12 | 0.0326988 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0312855 |
| CCNY | cyclin Y | 0.0306845 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0306843 |
| RTN3 | reticulon 3 | 0.0304846 |
| BBX | bobby sox homolog (Drosophila) | 0.0304096 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0301505 |
| SP100 | SP100 nuclear antigen | 0.0299262 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0294349 |
| NEBL | nebulette | 0.0291903 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0289969 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0284179 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0279477 |
| KRT86 | keratin 86, type II | 0.0277817 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0270801 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0269858 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0266813 |
| FOXO3 | forkhead box O3 | 0.0266577 |
| TPD52 | tumor protein D52 | 0.026446 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0263966 |
| RAD51B | RAD51 paralog B | 0.0263541 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256401 |
| HELZ | helicase with zinc finger | 0.025229 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0250608 |
| ADIPOR2 | adiponectin receptor 2 | 0.0244695 |
| ANKRD11 | ankyrin repeat domain 11 | 0.02427 |
| FAM13A | family with sequence similarity 13, member A | 0.0242442 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0240623 |
| ATF6 | activating transcription factor 6 | 0.0238265 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0238036 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0237062 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0236445 |
| CDK13 | cyclin-dependent kinase 13 | 0.0235785 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0234219 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0233546 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0231698 |
| MSI2 | musashi RNA-binding protein 2 | 0.0231276 |
| CLTC | clathrin, heavy chain (Hc) | 0.0230734 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0228267 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0228188 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.022585 |
| RCOR1 | REST corepressor 1 | 0.0221912 |
| USO1 | USO1 vesicle transport factor | 0.0220437 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219826 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0219784 |
| YAP1 | Yes-associated protein 1 | 0.0217699 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.021683 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0216193 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0215943 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0215834 |
| EFNA5 | ephrin-A5 | 0.0214862 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0214696 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0213417 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.0213272 |
| SHROOM3 | shroom family member 3 | 0.0212525 |
| AEBP2 | AE binding protein 2 | 0.0210355 |
| ZNF207 | zinc finger protein 207 | 0.0210129 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0209432 |
| GOLGB1 | golgin B1 | 0.0208875 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.020867 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0206261 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0204941 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0204816 |
| STXBP4 | syntaxin binding protein 4 | 0.0202451 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0199076 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0198536 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0198358 |
| EXOC4 | exocyst complex component 4 | 0.0198168 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.019761 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0196603 |
| ZNF292 | zinc finger protein 292 | 0.0195246 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0193386 |
| PARD3 | par-3 family cell polarity regulator | 0.0193108 |
| FNIP1 | folliculin interacting protein 1 | 0.0192559 |
| FAM219A | family with sequence similarity 219, member A | 0.0191987 |
| PRELID2 | PRELI domain containing 2 | 0.0191716 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0191655 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.019126 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0186884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.291942 |
| RPL19 | ribosomal protein L19 | -0.227361 |
| PTMA | prothymosin, alpha | -0.0826863 |
| TMSB10 | thymosin beta 10 | -0.0699927 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0695759 |
| RPS3 | ribosomal protein S3 | -0.0667159 |
| RPL12 | ribosomal protein L12 | -0.056308 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0513941 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0509998 |
| MT2A | metallothionein 2A | -0.0505308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0477023 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0455298 |
| RPL35A | ribosomal protein L35a | -0.0442296 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0439697 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0401925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0384303 |
| RPS19 | ribosomal protein S19 | -0.0383743 |
| TXNRD1 | thioredoxin reductase 1 | -0.0383034 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0381833 |
| TMSB4X | thymosin beta 4, X-linked | -0.0372663 |
| ACTG1 | actin gamma 1 | -0.0359358 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0358111 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0347489 |
| RPS6 | ribosomal protein S6 | -0.0342938 |
| RPS12 | ribosomal protein S12 | -0.0337469 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0326415 |
| NTN4 | netrin 4 | -0.0324463 |
| PFDN4 | prefoldin subunit 4 | -0.0322122 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0318204 |
| RPS8 | ribosomal protein S8 | -0.0309178 |
| OSMR | oncostatin M receptor | -0.0308854 |
| S100A9 | S100 calcium binding protein A9 | -0.0306914 |
| SET | SET nuclear proto-oncogene | -0.0299594 |
| RPL35 | ribosomal protein L35 | -0.0295384 |
| RPL37 | ribosomal protein L37 | -0.0294438 |
| AREG | amphiregulin | -0.0291301 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0291272 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0289692 |
| B2M | beta-2-microglobulin | -0.027968 |
| KLF6 | Kruppel-like factor 6 | -0.0279644 |
| S100A14 | S100 calcium binding protein A14 | -0.027253 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0270178 |
| KRT19 | keratin 19, type I | -0.0269388 |
| RPL26 | ribosomal protein L26 | -0.0265871 |
| FTL | ferritin, light polypeptide | -0.0264184 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0257939 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0248591 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0245305 |
| S100A8 | S100 calcium binding protein A8 | -0.0242118 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0241203 |
| RPL8 | ribosomal protein L8 | -0.0239444 |
| RPL34 | ribosomal protein L34 | -0.0239259 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0238441 |
| RPS27 | ribosomal protein S27 | -0.0235693 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0231913 |
| DSTN | destrin (actin depolymerizing factor) | -0.0226455 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0225737 |
| CBX3 | chromobox homolog 3 | -0.0222763 |
| S100A6 | S100 calcium binding protein A6 | -0.02214 |
| RPLP2 | ribosomal protein, large, P2 | -0.0220062 |
| RPL9 | ribosomal protein L9 | -0.021865 |
| RPL37A | ribosomal protein L37a | -0.0215113 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.02149 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0214291 |
| RPS29 | ribosomal protein S29 | -0.0210383 |
| CD63 | CD63 molecule | -0.0207989 |
| RPL36A | ribosomal protein L36a | -0.0207973 |
| RPL36 | ribosomal protein L36 | -0.0207303 |
| VIM | vimentin | -0.0203106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0202383 |
| RACK1 | receptor for activated C kinase 1 | -0.0201021 |
| RPS17 | ribosomal protein S17 | -0.0200226 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.020011 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0197847 |
| RPS2 | ribosomal protein S2 | -0.0197586 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0195786 |
| RPL31 | ribosomal protein L31 | -0.0193284 |
| RPL7 | ribosomal protein L7 | -0.0191242 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0190129 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0189179 |
| RPL32 | ribosomal protein L32 | -0.0188224 |
| RPS14 | ribosomal protein S14 | -0.0187865 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0187256 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0186367 |
| RPS24 | ribosomal protein S24 | -0.0185558 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181307 |
| MIEN1 | migration and invasion enhancer 1 | -0.0180458 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0179545 |
| SERF2 | small EDRK-rich factor 2 | -0.017953 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0178397 |
| RPL7A | ribosomal protein L7a | -0.0177528 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0176965 |
| ASPH | aspartate beta-hydroxylase | -0.0175845 |
| EGR1 | early growth response 1 | -0.0174915 |
| RPL30 | ribosomal protein L30 | -0.0174377 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0171763 |
| RPL11 | ribosomal protein L11 | -0.0170619 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0168412 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0168143 |
| S100A11 | S100 calcium binding protein A11 | -0.0166588 |
