| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.19585 |
| FAM13A | family with sequence similarity 13, member A | 0.113836 |
| MEF2A | myocyte enhancer factor 2A | 0.0973646 |
| VMP1 | vacuole membrane protein 1 | 0.0949531 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0929983 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0908315 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0882717 |
| TLE4 | transducin-like enhancer of split 4 | 0.0874672 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0833588 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0766154 |
| CRH | corticotropin releasing hormone | 0.0742555 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0722084 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0717725 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0706163 |
| DTNA | dystrobrevin, alpha | 0.0694756 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0688479 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0638094 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0634035 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0617938 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0590998 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0558573 |
| SP100 | SP100 nuclear antigen | 0.0537243 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0532891 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0523228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0512451 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0509981 |
| TPM1 | tropomyosin 1 (alpha) | 0.050593 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0495642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.049092 |
| PCBP2 | poly(rC) binding protein 2 | 0.0468851 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0466322 |
| EGR1 | early growth response 1 | 0.046182 |
| RPS6 | ribosomal protein S6 | 0.0455191 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0451391 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0441237 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0424645 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0419368 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.040168 |
| AMOTL1 | angiomotin like 1 | 0.0392424 |
| HELZ | helicase with zinc finger | 0.0391147 |
| ZNF148 | zinc finger protein 148 | 0.0383631 |
| THBS1 | thrombospondin 1 | 0.0382018 |
| FRMD5 | FERM domain containing 5 | 0.0380776 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0379875 |
| RNF145 | ring finger protein 145 | 0.0378164 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0375429 |
| MCL1 | myeloid cell leukemia 1 | 0.0375142 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0372913 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0369992 |
| ASPH | aspartate beta-hydroxylase | 0.036436 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0352441 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0352169 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0350189 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0349682 |
| QKI | QKI, KH domain containing, RNA binding | 0.0348485 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0346315 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0346156 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0345242 |
| INTS6 | integrator complex subunit 6 | 0.0344924 |
| FLT1 | fms-related tyrosine kinase 1 | 0.034441 |
| MYO1E | myosin IE | 0.0344203 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0341257 |
| FERMT2 | fermitin family member 2 | 0.0338732 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0338403 |
| MED13 | mediator complex subunit 13 | 0.033772 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0335358 |
| EHBP1 | EH domain binding protein 1 | 0.0335263 |
| VEGFA | vascular endothelial growth factor A | 0.0332049 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0330739 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0325781 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0323523 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.032244 |
| RAD51B | RAD51 paralog B | 0.0321843 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0321469 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0320615 |
| SIK3 | SIK family kinase 3 | 0.0316646 |
| FAM162A | family with sequence similarity 162, member A | 0.0314901 |
| B2M | beta-2-microglobulin | 0.0314658 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0313643 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0312998 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0307787 |
| RCOR1 | REST corepressor 1 | 0.0306039 |
| PCM1 | pericentriolar material 1 | 0.0304045 |
| PCBP3 | poly(rC) binding protein 3 | 0.0303796 |
| TPM4 | tropomyosin 4 | 0.0302422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0299762 |
| DNM3 | dynamin 3 | 0.0297235 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0294188 |
| SIK2 | salt-inducible kinase 2 | 0.0293994 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0293384 |
| SETBP1 | SET binding protein 1 | 0.0291883 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0291324 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0289483 |
| RPL19 | ribosomal protein L19 | 0.0285477 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0282682 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0281861 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279489 |
| SETD5 | SET domain containing 5 | 0.0279039 |
| HIP1 | huntingtin interacting protein 1 | 0.0275633 |
| TOP1 | topoisomerase (DNA) I | 0.0272567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEIS2 | Meis homeobox 2 | -0.0974986 |
| COL1A1 | collagen, type I, alpha 1 | -0.0929412 |
| SYT1 | synaptotagmin I | -0.090828 |
| PTMA | prothymosin, alpha | -0.088299 |
| ACTG1 | actin gamma 1 | -0.0880749 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0826389 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.07508 |
| LPIN1 | lipin 1 | -0.0712369 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0661868 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0659214 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0654071 |
| AOPEP | aminopeptidase O (putative) | -0.0648842 |
| FMN1 | formin 1 | -0.0638264 |
| GOLGA4 | golgin A4 | -0.0568236 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0538069 |
| STC1 | stanniocalcin 1 | -0.0517552 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0514397 |
| TMSB10 | thymosin beta 10 | -0.0496421 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0482049 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0477357 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0475118 |
| H3-3B | H3.3 histone B | -0.0440869 |
| CADM2 | cell adhesion molecule 2 | -0.0439086 |
| VIM | vimentin | -0.043108 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0429898 |
| RPL38 | ribosomal protein L38 | -0.0419741 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0413089 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0411984 |
| CCND1 | cyclin D1 | -0.0404367 |
| LSAMP | limbic system-associated membrane protein | -0.0399792 |
| MATR3 | matrin 3 | -0.0398101 |
| PHF3 | PHD finger protein 3 | -0.0395321 |
| MT2A | metallothionein 2A | -0.0388617 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0381572 |
| GNAS | GNAS complex locus | -0.0372509 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0371534 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0371081 |
| RPS24 | ribosomal protein S24 | -0.0368049 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359373 |
| USP3 | ubiquitin specific peptidase 3 | -0.0359007 |
| ATXN10 | ataxin 10 | -0.0357242 |
| RPL4 | ribosomal protein L4 | -0.0351224 |
| PDE8A | phosphodiesterase 8A | -0.0349332 |
| NRP1 | neuropilin 1 | -0.0347336 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0343607 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0340526 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0339625 |
| COL3A1 | collagen, type III, alpha 1 | -0.033274 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0323725 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0321669 |
| TBX2 | T-box 2 | -0.031675 |
| KLF6 | Kruppel-like factor 6 | -0.031195 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0308212 |
| HMGA1 | high mobility group AT-hook 1 | -0.0308046 |
| RNF213 | ring finger protein 213 | -0.0306673 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0306425 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0304209 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.030193 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301832 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.029716 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0294195 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0291072 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0289537 |
| MAP1B | microtubule-associated protein 1B | -0.0288407 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0287665 |
| NRG1 | neuregulin 1 | -0.0285775 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0285554 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0284539 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0283125 |
| RPL34 | ribosomal protein L34 | -0.0282238 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0282035 |
| ZNF804A | zinc finger protein 804A | -0.0278643 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.027693 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0273269 |
| SYNJ2 | synaptojanin 2 | -0.0272795 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0272536 |
| ANXA2 | annexin A2 | -0.0269464 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0266619 |
| AFDN | afadin, adherens junction formation factor | -0.0265242 |
| PHOX2B | paired-like homeobox 2b | -0.0260975 |
| KIF21A | kinesin family member 21A | -0.0260198 |
| OSMR | oncostatin M receptor | -0.025776 |
| TRIB2 | tribbles pseudokinase 2 | -0.0257209 |
| BMERB1 | bMERB domain containing 1 | -0.0256398 |
| PRSS3 | protease, serine, 3 | -0.0253716 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0250796 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0250688 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0249333 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0248155 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0248058 |
| CDC27 | cell division cycle 27 | -0.0246037 |
| ANGPT1 | angiopoietin 1 | -0.0245873 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0244887 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0242259 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0240624 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0237323 |
| RO60 | Ro60, Y RNA binding protein | -0.0237291 |
| TOX | thymocyte selection-associated high mobility group box | -0.0236747 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0234438 |
| KLHL5 | kelch-like family member 5 | -0.0233023 |
