| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.339538 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.134309 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.130342 |
| INTS6 | integrator complex subunit 6 | 0.115867 |
| MYO1E | myosin IE | 0.101883 |
| ANXA2 | annexin A2 | 0.101361 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.098651 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0939955 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0814229 |
| EGR1 | early growth response 1 | 0.079833 |
| SMAD3 | SMAD family member 3 | 0.079666 |
| EZR | ezrin | 0.0788288 |
| RNF213 | ring finger protein 213 | 0.0760865 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0695909 |
| EFNB2 | ephrin-B2 | 0.068397 |
| TJP1 | tight junction protein 1 | 0.0683048 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0675319 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0649785 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0608385 |
| VCL | vinculin | 0.0579543 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0577213 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0548752 |
| RIGI | RNA sensor RIG-I | 0.0537167 |
| FNDC3B | fibronectin type III domain containing 3B | 0.052817 |
| SPAG9 | sperm associated antigen 9 | 0.0516982 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0512044 |
| KYNU | kynureninase | 0.050686 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0490668 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0483876 |
| SQSTM1 | sequestosome 1 | 0.0458612 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0454388 |
| MX2 | MX dynamin-like GTPase 2 | 0.0453181 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0450475 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0434688 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0427536 |
| VMP1 | vacuole membrane protein 1 | 0.0425996 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0423644 |
| ETV6 | ets variant 6 | 0.0419994 |
| DUSP10 | dual specificity phosphatase 10 | 0.0408406 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0400511 |
| USP53 | ubiquitin specific peptidase 53 | 0.0399507 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.039205 |
| LIPH | lipase, member H | 0.0359407 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0340615 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0340475 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0326609 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0326109 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0319725 |
| UBAP2 | ubiquitin associated protein 2 | 0.0316176 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0315201 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0312846 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0308736 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0304278 |
| AREG | amphiregulin | 0.0301708 |
| NABP1 | nucleic acid binding protein 1 | 0.0301341 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0300758 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0300121 |
| MCU | mitochondrial calcium uniporter | 0.0297502 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0296659 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0296237 |
| PRKCA | protein kinase C, alpha | 0.0295008 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0290637 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0290616 |
| MORF4L2 | mortality factor 4 like 2 | 0.0278786 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0275961 |
| LIMA1 | LIM domain and actin binding 1 | 0.0275885 |
| TRIM2 | tripartite motif containing 2 | 0.0274774 |
| TNNC1 | troponin C type 1 (slow) | 0.0274072 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0273972 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0270482 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0270456 |
| SIK3 | SIK family kinase 3 | 0.0270295 |
| B2M | beta-2-microglobulin | 0.0269697 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0267398 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0265927 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.026501 |
| ANXA1 | annexin A1 | 0.0264815 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262585 |
| TMC5 | transmembrane channel-like 5 | 0.0261127 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0261057 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.02606 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0257886 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0251261 |
| MYO5B | myosin VB | 0.0250857 |
| OXSR1 | oxidative stress responsive 1 | 0.0250509 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0249399 |
| SLK | STE20-like kinase | 0.0245945 |
| TUT7 | terminal uridylyl transferase 7 | 0.0242108 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0240553 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0240355 |
| SEC24A | SEC24 family member A | 0.0240168 |
| APOL1 | apolipoprotein L, 1 | 0.0238191 |
| DIAPH1 | diaphanous-related formin 1 | 0.0237932 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0237395 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0237229 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0236995 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0236953 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0236517 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0234446 |
| POF1B | premature ovarian failure, 1B | 0.0233363 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.155377 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.112879 |
| PTMA | prothymosin, alpha | -0.103632 |
| RPS6 | ribosomal protein S6 | -0.0789999 |
| FTL | ferritin, light polypeptide | -0.0774709 |
| HLA-B | major histocompatibility complex, class I, B | -0.0771164 |
| RPL35A | ribosomal protein L35a | -0.0673276 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0668129 |
| TXNRD1 | thioredoxin reductase 1 | -0.0646771 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.058974 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0541219 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0524341 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515618 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0505322 |
| TMSB10 | thymosin beta 10 | -0.0502187 |
| RUNX1 | runt-related transcription factor 1 | -0.0471319 |
| RNF43 | ring finger protein 43 | -0.0463703 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0451666 |
| NDRG1 | N-myc downstream regulated 1 | -0.0441732 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0438607 |
| LYZ | lysozyme | -0.0429567 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0429193 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0421293 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0417716 |
| LCN2 | lipocalin 2 | -0.0409149 |
| PHF3 | PHD finger protein 3 | -0.0400894 |
| H1-0 | H1.0 linker histone | -0.0400086 |
| RPL34 | ribosomal protein L34 | -0.0390378 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0383534 |
| HLA-C | major histocompatibility complex, class I, C | -0.0372593 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.037219 |
| RPS8 | ribosomal protein S8 | -0.0369119 |
| PTGR1 | prostaglandin reductase 1 | -0.0366591 |
| RPL23 | ribosomal protein L23 | -0.0362657 |
| GNAS | GNAS complex locus | -0.0361672 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0360438 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0355292 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0354023 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0346228 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0334528 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332896 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0331863 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0329831 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0327611 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0327028 |
| CANX | calnexin | -0.0320029 |
| RPS3 | ribosomal protein S3 | -0.031633 |
| RPL12 | ribosomal protein L12 | -0.0313915 |
| EPCAM | epithelial cell adhesion molecule | -0.0313401 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0307483 |
| SBF2 | SET binding factor 2 | -0.0306735 |
| RPS12 | ribosomal protein S12 | -0.0306169 |
| RPS13 | ribosomal protein S13 | -0.0304371 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0302839 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0302699 |
| RPS24 | ribosomal protein S24 | -0.0301096 |
| KLHL24 | kelch-like family member 24 | -0.0300847 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0295709 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0288143 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0285373 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0283393 |
| S100A6 | S100 calcium binding protein A6 | -0.0279815 |
| XAF1 | XIAP associated factor 1 | -0.0278937 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278099 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0275343 |
| DIAPH3 | diaphanous-related formin 3 | -0.0275059 |
| RBM39 | RNA binding motif protein 39 | -0.0271428 |
| NCKAP5 | NCK-associated protein 5 | -0.0269327 |
| AOPEP | aminopeptidase O (putative) | -0.0265702 |
| UBAC2 | UBA domain containing 2 | -0.0263854 |
| RAD51B | RAD51 paralog B | -0.0263586 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0262171 |
| RPL31 | ribosomal protein L31 | -0.026161 |
| AHNAK | AHNAK nucleoprotein | -0.0257414 |
| RPS29 | ribosomal protein S29 | -0.0251742 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0251283 |
| BRCA2 | breast cancer 2, early onset | -0.0250839 |
| RPS11 | ribosomal protein S11 | -0.0250745 |
| RPL19 | ribosomal protein L19 | -0.0250251 |
| MUC20 | mucin 20, cell surface associated | -0.0249397 |
| RPL38 | ribosomal protein L38 | -0.0248332 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0247507 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0247476 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0245754 |
| RPS16 | ribosomal protein S16 | -0.0245262 |
| RPL37A | ribosomal protein L37a | -0.0243742 |
| PCED1B | PC-esterase domain containing 1B | -0.0242234 |
| TMEM51 | transmembrane protein 51 | -0.0240933 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0240615 |
| SPATA13 | spermatogenesis associated 13 | -0.0240022 |
| TMEM62 | transmembrane protein 62 | -0.0239929 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0237719 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0237095 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0236377 |
| FOXP1 | forkhead box P1 | -0.0234947 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0234344 |
| CLYBL | citrate lyase beta like | -0.0234038 |
| RPL9 | ribosomal protein L9 | -0.0233843 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0232416 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0231132 |
