| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.281009 |
| EGFR | epidermal growth factor receptor | 0.201683 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.118928 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0923529 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0838574 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0825091 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.081994 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0813169 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0726704 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0702876 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0601422 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0559046 |
| DST | dystonin | 0.0502877 |
| MMP12 | matrix metallopeptidase 12 | 0.0476504 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0475773 |
| EGR1 | early growth response 1 | 0.0470374 |
| GOLGB1 | golgin B1 | 0.0469163 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0457202 |
| CADM1 | cell adhesion molecule 1 | 0.0433247 |
| FAM13A | family with sequence similarity 13, member A | 0.0383469 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0382329 |
| FAM107B | family with sequence similarity 107, member B | 0.0381146 |
| LOXL2 | lysyl oxidase-like 2 | 0.037617 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0375794 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0369186 |
| GPATCH2L | G patch domain containing 2-like | 0.0368561 |
| ZNF395 | zinc finger protein 395 | 0.0367842 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.036682 |
| DENND4A | DENN/MADD domain containing 4A | 0.0365254 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0361909 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0361458 |
| TNS3 | tensin 3 | 0.0361317 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0360903 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0360612 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0359081 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.034902 |
| MYO1B | myosin IB | 0.0339393 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0338767 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0337986 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0336893 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0334178 |
| MYOF | myoferlin | 0.0326429 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.032412 |
| LDHA | lactate dehydrogenase A | 0.0322817 |
| HDAC9 | histone deacetylase 9 | 0.0319633 |
| NABP1 | nucleic acid binding protein 1 | 0.0313041 |
| ANXA2 | annexin A2 | 0.0306221 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0303752 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.029822 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0297995 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0295804 |
| HLA-B | major histocompatibility complex, class I, B | 0.0287039 |
| FRMD4A | FERM domain containing 4A | 0.0287038 |
| DTNA | dystrobrevin, alpha | 0.0282297 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0278464 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0278035 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0271867 |
| CDK6 | cyclin-dependent kinase 6 | 0.0271773 |
| CPNE1 | copine I | 0.0267518 |
| TUT4 | terminal uridylyl transferase 4 | 0.0265714 |
| COPA | coatomer protein complex, subunit alpha | 0.026514 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0261829 |
| HELZ | helicase with zinc finger | 0.026134 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.025899 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0255784 |
| MYLK | myosin light chain kinase | 0.0250713 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0246966 |
| FNIP1 | folliculin interacting protein 1 | 0.0246296 |
| HLA-A | major histocompatibility complex, class I, A | 0.024532 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0242128 |
| MAGT1 | magnesium transporter 1 | 0.0241098 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.024072 |
| ZNF292 | zinc finger protein 292 | 0.0239943 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.023977 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0236632 |
| HIP1 | huntingtin interacting protein 1 | 0.023653 |
| GDF15 | growth differentiation factor 15 | 0.0235697 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0235166 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0231212 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0230645 |
| PLIN2 | perilipin 2 | 0.0229925 |
| NAV3 | neuron navigator 3 | 0.0229667 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0229485 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0229355 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0229191 |
| TPM4 | tropomyosin 4 | 0.0226937 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0226926 |
| SMYD3 | SET and MYND domain containing 3 | 0.0225592 |
| ATF4 | activating transcription factor 4 | 0.0224547 |
| DYM | dymeclin | 0.0224118 |
| PCNX4 | pecanex 4 | 0.0221585 |
| GPC5 | glypican 5 | 0.0220582 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0220176 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0214474 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0213583 |
| GOLGA4 | golgin A4 | 0.0210465 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0210017 |
| JMJD1C | jumonji domain containing 1C | 0.0209537 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0209336 |
| FBXO11 | F-box protein 11 | 0.0208532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.126119 |
| MT2A | metallothionein 2A | -0.113521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110694 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.10464 |
| AHNAK | AHNAK nucleoprotein | -0.0981486 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0790449 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0753831 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.069043 |
| TMSB10 | thymosin beta 10 | -0.0689109 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0652024 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0635439 |
| RPS27A | ribosomal protein S27a | -0.0599474 |
| AUTS2 | autism susceptibility candidate 2 | -0.0588451 |
| CANX | calnexin | -0.0571591 |
| UBC | ubiquitin C | -0.0505702 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0505688 |
| MT1X | metallothionein 1X | -0.0503615 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0460004 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0459137 |
| TXNRD1 | thioredoxin reductase 1 | -0.0454963 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0454556 |
| PTMA | prothymosin, alpha | -0.0439057 |
| PTK2 | protein tyrosine kinase 2 | -0.0427358 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0423648 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0421167 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0414418 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0411322 |
| TXNIP | thioredoxin interacting protein | -0.0389967 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0375403 |
| RPS3 | ribosomal protein S3 | -0.0362987 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0362793 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0355902 |
| KYNU | kynureninase | -0.0355173 |
| NLGN1 | neuroligin 1 | -0.0353725 |
| CD44 | CD44 molecule (Indian blood group) | -0.0343561 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0339544 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.033825 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0336351 |
| STK17A | serine/threonine kinase 17a | -0.0335914 |
| TCF12 | transcription factor 12 | -0.0325793 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0325593 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0320741 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.031924 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0314311 |
| PHF14 | PHD finger protein 14 | -0.0314068 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.031051 |
| SDC4 | syndecan 4 | -0.0307173 |
| ZNF841 | zinc finger protein 841 | -0.0303518 |
| SYT1 | synaptotagmin I | -0.0302086 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0299213 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0297836 |
| PLEC | plectin | -0.0297464 |
| GLCCI1 | glucocorticoid induced 1 | -0.0294896 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0294801 |
| RPLP2 | ribosomal protein, large, P2 | -0.0294356 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0293359 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0293321 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0292313 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0287446 |
| RACK1 | receptor for activated C kinase 1 | -0.0284211 |
| RPL28 | ribosomal protein L28 | -0.0283762 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0283408 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0282662 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0275812 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0275278 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0274255 |
| RPL23 | ribosomal protein L23 | -0.0273998 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0272002 |
| CEP128 | centrosomal protein 128kDa | -0.0271943 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0271589 |
| EHBP1 | EH domain binding protein 1 | -0.0270915 |
| URI1 | URI1, prefoldin-like chaperone | -0.0269974 |
| FTL | ferritin, light polypeptide | -0.0269174 |
| ASPH | aspartate beta-hydroxylase | -0.0267315 |
| APP | amyloid beta (A4) precursor protein | -0.0265948 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0265947 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0265667 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.025907 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0255271 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0254808 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0253689 |
| GANAB | glucosidase, alpha; neutral AB | -0.025196 |
| VCL | vinculin | -0.025167 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0251503 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.025093 |
| RPL12 | ribosomal protein L12 | -0.0250832 |
| FAF2 | Fas associated factor family member 2 | -0.0250595 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0248866 |
| PCBP3 | poly(rC) binding protein 3 | -0.0245382 |
| WWOX | WW domain containing oxidoreductase | -0.0245314 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0245275 |
| ACTN1 | actinin, alpha 1 | -0.0245104 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0244515 |
| BRD4 | bromodomain containing 4 | -0.0243448 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0243423 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0239032 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0238023 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0237678 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0237186 |
| PARVA | parvin, alpha | -0.0236988 |
