| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.190998 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.160792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.156731 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.124323 |
| ENO1 | enolase 1, (alpha) | 0.123615 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120525 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.1114 |
| ASPH | aspartate beta-hydroxylase | 0.0825652 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0804387 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0756992 |
| NAV1 | neuron navigator 1 | 0.0691818 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.068196 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.055278 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0540956 |
| CALR | calreticulin | 0.0540893 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0540256 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0524079 |
| STC1 | stanniocalcin 1 | 0.0523628 |
| COL5A1 | collagen, type V, alpha 1 | 0.050925 |
| CANX | calnexin | 0.0496517 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0479416 |
| PRELID2 | PRELI domain containing 2 | 0.0474544 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0471147 |
| WWOX | WW domain containing oxidoreductase | 0.0464118 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0452182 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.044787 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0440923 |
| COL6A3 | collagen, type VI, alpha 3 | 0.042748 |
| HMGA2 | high mobility group AT-hook 2 | 0.0422622 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0378933 |
| INTS6 | integrator complex subunit 6 | 0.0376472 |
| RUNX1 | runt-related transcription factor 1 | 0.0372394 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0361331 |
| NAV2 | neuron navigator 2 | 0.0345026 |
| PRKCA | protein kinase C, alpha | 0.033642 |
| TPM3 | tropomyosin 3 | 0.0331383 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0330315 |
| LDHA | lactate dehydrogenase A | 0.0329053 |
| GPC5 | glypican 5 | 0.0320091 |
| PTK2 | protein tyrosine kinase 2 | 0.0314124 |
| SQSTM1 | sequestosome 1 | 0.0313491 |
| RRM2 | ribonucleotide reductase M2 | 0.0310232 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0308099 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304243 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0302753 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.030105 |
| MCL1 | myeloid cell leukemia 1 | 0.0298515 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.029745 |
| DTNA | dystrobrevin, alpha | 0.0293295 |
| ATXN1 | ataxin 1 | 0.0292932 |
| RAD51B | RAD51 paralog B | 0.0291931 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0290544 |
| TNS1 | tensin 1 | 0.0290392 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0289858 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0289382 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0288549 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0284316 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0283568 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0283466 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.028264 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0277082 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276762 |
| DIAPH2 | diaphanous-related formin 2 | 0.0276004 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0271727 |
| ZNF638 | zinc finger protein 638 | 0.0264827 |
| FRMD4A | FERM domain containing 4A | 0.0262422 |
| PRSS23 | protease, serine, 23 | 0.0261456 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0260831 |
| RCOR1 | REST corepressor 1 | 0.0260718 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0259797 |
| DST | dystonin | 0.0259179 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0253506 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0251301 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0250246 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0249104 |
| GOLGB1 | golgin B1 | 0.0249031 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0248962 |
| CFAP20DC | CFAP20 domain containing | 0.0245941 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.024176 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0241526 |
| HDAC9 | histone deacetylase 9 | 0.0241262 |
| PCBP2 | poly(rC) binding protein 2 | 0.023965 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0235759 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023194 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0231414 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0231298 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0231292 |
| AEBP2 | AE binding protein 2 | 0.023062 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0228432 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0227912 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0225974 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0225544 |
| LRRC23 | leucine rich repeat containing 23 | 0.0225392 |
| PKM | pyruvate kinase, muscle | 0.0224999 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0224861 |
| B2M | beta-2-microglobulin | 0.022378 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0221085 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0218752 |
| CENPF | centromere protein F, 350/400kDa | 0.021764 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0213782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.338287 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.297864 |
| FN1 | fibronectin 1 | -0.214319 |
| TMSB10 | thymosin beta 10 | -0.137895 |
| CD44 | CD44 molecule (Indian blood group) | -0.111244 |
| NDRG1 | N-myc downstream regulated 1 | -0.0972576 |
| MT2A | metallothionein 2A | -0.0914687 |
| TENM2 | teneurin transmembrane protein 2 | -0.0730123 |
| IGF2 | insulin-like growth factor 2 | -0.0652182 |
| GLIS3 | GLIS family zinc finger 3 | -0.0651506 |
| EGR1 | early growth response 1 | -0.0620577 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0579248 |
| LOX | lysyl oxidase | -0.0464598 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0460836 |
| ACTG1 | actin gamma 1 | -0.0458266 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0448362 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0443721 |
| SBF2 | SET binding factor 2 | -0.0441402 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0431923 |
| RTN4 | reticulon 4 | -0.0428002 |
| TNNC1 | troponin C type 1 (slow) | -0.0426821 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0423013 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0376134 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0367563 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0365124 |
| OSMR | oncostatin M receptor | -0.0364951 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0363598 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.036277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0348511 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0343793 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0340534 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0331866 |
| MT1X | metallothionein 1X | -0.0328126 |
| CCND1 | cyclin D1 | -0.0319146 |
| RNF24 | ring finger protein 24 | -0.0316185 |
| RPL35A | ribosomal protein L35a | -0.0306767 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0305482 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.02803 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0277534 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0255994 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0255845 |
| ACTN4 | actinin, alpha 4 | -0.025552 |
| CD109 | CD109 molecule | -0.0253787 |
| RNF149 | ring finger protein 149 | -0.0253773 |
| TUBB | tubulin, beta class I | -0.0252416 |
| IL1B | interleukin 1, beta | -0.0246861 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0245109 |
| RPS19 | ribosomal protein S19 | -0.024415 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0243346 |
| WDR45B | WD repeat domain 45B | -0.0242869 |
| USP3 | ubiquitin specific peptidase 3 | -0.0241761 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.023996 |
| RRBP1 | ribosome binding protein 1 | -0.0238136 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0232502 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.023203 |
| VIM | vimentin | -0.0228825 |
| SPAG9 | sperm associated antigen 9 | -0.021993 |
| PLEC | plectin | -0.0218481 |
| TUBB6 | tubulin, beta 6 class V | -0.0216938 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.021101 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0209726 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.020868 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0208043 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0201187 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0198741 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0197124 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0192581 |
| RASA3 | RAS p21 protein activator 3 | -0.0187807 |
| YBX3 | Y box binding protein 3 | -0.0185445 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0184969 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0184939 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.018419 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0183066 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0181849 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0180209 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0175777 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0173728 |
| AGRN | agrin | -0.017284 |
| DUSP6 | dual specificity phosphatase 6 | -0.0172588 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0172017 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | -0.017083 |
| RLF | rearranged L-myc fusion | -0.0166753 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0165077 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0163919 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0162127 |
| TMEM165 | transmembrane protein 165 | -0.0159772 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0159005 |
| TUBA1B | tubulin, alpha 1b | -0.0156111 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0153854 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0152866 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0151144 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0149164 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0148795 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0148373 |
| TXNIP | thioredoxin interacting protein | -0.0147028 |
| BSG | basigin (Ok blood group) | -0.0145886 |
| TMEM41B | transmembrane protein 41B | -0.0145628 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0145598 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0144255 |
| CDK17 | cyclin-dependent kinase 17 | -0.0143831 |
