| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.230831 |
| CADM1 | cell adhesion molecule 1 | 0.180818 |
| NDRG1 | N-myc downstream regulated 1 | 0.157722 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.155704 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.120413 |
| CDH13 | cadherin 13 | 0.112971 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.108136 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.09969 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0899997 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0763891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0640191 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0568914 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0529082 |
| QKI | QKI, KH domain containing, RNA binding | 0.0501076 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0493298 |
| NAV2 | neuron navigator 2 | 0.0485239 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0450621 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0433649 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0427244 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0417929 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0417741 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0409328 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.040549 |
| TRAM1 | translocation associated membrane protein 1 | 0.0398521 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0390846 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.039056 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0385897 |
| PTK2 | protein tyrosine kinase 2 | 0.0378267 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0375941 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0371798 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0371098 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0370613 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0369427 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0368219 |
| FMNL2 | formin-like 2 | 0.0360954 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0359567 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0349768 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0347289 |
| EGFR | epidermal growth factor receptor | 0.0346192 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0344828 |
| SETD5 | SET domain containing 5 | 0.0340561 |
| COPA | coatomer protein complex, subunit alpha | 0.0337088 |
| CCNY | cyclin Y | 0.0333445 |
| SPAG9 | sperm associated antigen 9 | 0.0330218 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0327911 |
| USP3 | ubiquitin specific peptidase 3 | 0.0322381 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0319915 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0317252 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0316379 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0308831 |
| MRTFA | myocardin related transcription factor A | 0.0306493 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0305371 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.029988 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0298536 |
| PDE10A | phosphodiesterase 10A | 0.0297619 |
| ZNF292 | zinc finger protein 292 | 0.0296966 |
| SESN2 | sestrin 2 | 0.0296581 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0293695 |
| RTN4 | reticulon 4 | 0.0293677 |
| HYOU1 | hypoxia up-regulated 1 | 0.0292372 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0291951 |
| BBX | bobby sox homolog (Drosophila) | 0.0290287 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.028866 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0287946 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286936 |
| OGA | O-GlcNAcase | 0.028672 |
| HIP1 | huntingtin interacting protein 1 | 0.0282626 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0275003 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0272838 |
| VEGFA | vascular endothelial growth factor A | 0.0270871 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0270822 |
| MAP4 | microtubule-associated protein 4 | 0.0270658 |
| RYBP | RING1 and YY1 binding protein | 0.0269508 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0268575 |
| CLINT1 | clathrin interactor 1 | 0.0265262 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0265007 |
| MTDH | metadherin | 0.0264866 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0264195 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0263127 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.026229 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0262147 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0260075 |
| ANO10 | anoctamin 10 | 0.025665 |
| RND3 | Rho family GTPase 3 | 0.0254868 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0253946 |
| TFG | TRK-fused gene | 0.0253052 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0252593 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0251333 |
| CCNL1 | cyclin L1 | 0.025121 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0250698 |
| FAM13A | family with sequence similarity 13, member A | 0.0247076 |
| ADM | adrenomedullin | 0.0245491 |
| RASA2 | RAS p21 protein activator 2 | 0.0244882 |
| RIOK3 | RIO kinase 3 | 0.0244324 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.024341 |
| MYO1B | myosin IB | 0.0242129 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0241019 |
| MYO10 | myosin X | 0.0240477 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.024031 |
| FOXO3 | forkhead box O3 | 0.0240148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.194565 |
| FN1 | fibronectin 1 | -0.182444 |
| CD44 | CD44 molecule (Indian blood group) | -0.125893 |
| STC1 | stanniocalcin 1 | -0.123348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103306 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0988393 |
| COL1A1 | collagen, type I, alpha 1 | -0.0933656 |
| TMSB10 | thymosin beta 10 | -0.0788816 |
| VIM | vimentin | -0.0671708 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0661595 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0605403 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0554636 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0543759 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0517808 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0489118 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0488881 |
| COL1A2 | collagen, type I, alpha 2 | -0.047129 |
| GLIS3 | GLIS family zinc finger 3 | -0.0464443 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0461875 |
| RPS3 | ribosomal protein S3 | -0.0434161 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0425959 |
| HMGA2 | high mobility group AT-hook 2 | -0.0413898 |
| RRBP1 | ribosome binding protein 1 | -0.039863 |
| OSMR | oncostatin M receptor | -0.0398134 |
| INHBA | inhibin, beta A | -0.0395023 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0368905 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0351057 |
| CALR | calreticulin | -0.0330039 |
| RPL26 | ribosomal protein L26 | -0.0309733 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0303882 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0301675 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0295921 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0292122 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290076 |
| HAS2 | hyaluronan synthase 2 | -0.0279848 |
| RPL7 | ribosomal protein L7 | -0.0276711 |
| POSTN | periostin, osteoblast specific factor | -0.0275697 |
| RPS2 | ribosomal protein S2 | -0.0270455 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0266582 |
| COL3A1 | collagen, type III, alpha 1 | -0.0265749 |
| LDHA | lactate dehydrogenase A | -0.0264783 |
| TMSB4X | thymosin beta 4, X-linked | -0.0259907 |
| RPLP2 | ribosomal protein, large, P2 | -0.0255814 |
| FRMD4A | FERM domain containing 4A | -0.0251745 |
| RPL9 | ribosomal protein L9 | -0.0244793 |
| COL5A1 | collagen, type V, alpha 1 | -0.0242379 |
| ACTG1 | actin gamma 1 | -0.0237123 |
| S100A9 | S100 calcium binding protein A9 | -0.0232702 |
| CAVIN1 | caveolae associated protein 1 | -0.0231145 |
| RPL37A | ribosomal protein L37a | -0.0230067 |
| DUSP6 | dual specificity phosphatase 6 | -0.0229578 |
| RPS8 | ribosomal protein S8 | -0.0228439 |
| S100A6 | S100 calcium binding protein A6 | -0.0226396 |
| RPL30 | ribosomal protein L30 | -0.0221468 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0220464 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0220004 |
| B2M | beta-2-microglobulin | -0.0219216 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0216551 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0216379 |
| RPS19 | ribosomal protein S19 | -0.0213734 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212726 |
| RPS24 | ribosomal protein S24 | -0.0210703 |
| NAV1 | neuron navigator 1 | -0.0209921 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0202124 |
| SMAD3 | SMAD family member 3 | -0.0200351 |
| FAT1 | FAT atypical cadherin 1 | -0.0199496 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0195886 |
| NRP1 | neuropilin 1 | -0.019248 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0192035 |
| HLA-B | major histocompatibility complex, class I, B | -0.0191626 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0189668 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0189247 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0188399 |
| FAM20C | family with sequence similarity 20, member C | -0.0187854 |
| FTL | ferritin, light polypeptide | -0.0187284 |
| ENO1 | enolase 1, (alpha) | -0.018723 |
| LOC112694756 | uncharaterized LOC112694756 | -0.018556 |
| RPL12 | ribosomal protein L12 | -0.0183353 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0183323 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0181722 |
| RPL32 | ribosomal protein L32 | -0.0177639 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0177551 |
| RACK1 | receptor for activated C kinase 1 | -0.0177316 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0174851 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0174139 |
| RPL35A | ribosomal protein L35a | -0.017376 |
| IL6 | interleukin 6 | -0.0172925 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.017142 |
| RPL36 | ribosomal protein L36 | -0.0171386 |
| SERINC1 | serine incorporator 1 | -0.0168399 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0167057 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0163874 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0163848 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0162451 |
| CLMP | CXADR-like membrane protein | -0.0160387 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0159654 |
| TPI1 | triosephosphate isomerase 1 | -0.0159064 |
| MKI67 | marker of proliferation Ki-67 | -0.0157535 |
| LMNA | lamin A/C | -0.0157456 |
| STK38L | serine/threonine kinase 38 like | -0.0157119 |
