| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0924212 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0642196 |
| LMO7 | LIM domain 7 | 0.059157 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0575915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0515716 |
| LAMA4 | laminin, alpha 4 | 0.0423081 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0388927 |
| SMAD3 | SMAD family member 3 | 0.0386744 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.037634 |
| INTS6 | integrator complex subunit 6 | 0.0370245 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0361125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0279651 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0278803 |
| PRR5L | proline rich 5 like | 0.0277573 |
| CCNYL1 | cyclin Y-like 1 | 0.0277454 |
| FAT1 | FAT atypical cadherin 1 | 0.0274278 |
| PLK2 | polo-like kinase 2 | 0.025229 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0250684 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0247723 |
| SGMS2 | sphingomyelin synthase 2 | 0.024763 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0233914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0213912 |
| POF1B | premature ovarian failure, 1B | 0.0203475 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0200328 |
| HMGB2 | high mobility group box 2 | 0.0198273 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0195742 |
| CTBP2 | C-terminal binding protein 2 | 0.0195208 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.019398 |
| CENPF | centromere protein F, 350/400kDa | 0.0185986 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0182263 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0172595 |
| MKI67 | marker of proliferation Ki-67 | 0.01711 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0168414 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0162998 |
| SERINC5 | serine incorporator 5 | 0.0161679 |
| ECT2 | epithelial cell transforming 2 | 0.0159168 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0156692 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0156152 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0155542 |
| AREG | amphiregulin | 0.0150737 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0145376 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0144819 |
| WWOX | WW domain containing oxidoreductase | 0.0143675 |
| MMP7 | matrix metallopeptidase 7 | 0.0142179 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0142104 |
| EMP1 | epithelial membrane protein 1 | 0.0141762 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0139581 |
| KRT20 | keratin 20, type I | 0.0138924 |
| HOMER1 | homer scaffolding protein 1 | 0.0136391 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0136171 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0132695 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0131763 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0130851 |
| VCL | vinculin | 0.0129933 |
| DUSP16 | dual specificity phosphatase 16 | 0.0129803 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0129096 |
| RRM2 | ribonucleotide reductase M2 | 0.0126396 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0126181 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0125155 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0122381 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0119929 |
| FAM107B | family with sequence similarity 107, member B | 0.0117674 |
| UTRN | utrophin | 0.0116651 |
| KITLG | KIT ligand | 0.0116177 |
| TJP1 | tight junction protein 1 | 0.0115192 |
| EFNB2 | ephrin-B2 | 0.0114891 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0112457 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0112445 |
| PDE10A | phosphodiesterase 10A | 0.011209 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0111795 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0110247 |
| HMGB1 | high mobility group box 1 | 0.0109771 |
| CAPN8 | calpain 8 | 0.0108904 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0107041 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0106288 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0106269 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0106243 |
| RCOR1 | REST corepressor 1 | 0.0105586 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0101192 |
| SERTAD2 | SERTA domain containing 2 | 0.00996841 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.00996444 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.00988504 |
| CLPTM1L | CLPTM1-like | 0.00986971 |
| CENPE | centromere protein E, 312kDa | 0.00982705 |
| CLIC5 | chloride intracellular channel 5 | 0.00979838 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.00975487 |
| KRT18 | keratin 18, type I | 0.00967665 |
| TLE4 | transducin-like enhancer of split 4 | 0.00967335 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0096317 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00957992 |
| TUFT1 | tuftelin 1 | 0.00950804 |
| PDZD8 | PDZ domain containing 8 | 0.00948827 |
| NMUR2 | neuromedin U receptor 2 | 0.00945555 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0093696 |
| TENM1 | teneurin transmembrane protein 1 | 0.00931974 |
| NABP1 | nucleic acid binding protein 1 | 0.00910333 |
| NUCB2 | nucleobindin 2 | 0.00896937 |
| AGR2 | anterior gradient 2 | 0.00892946 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00891911 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00888996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.30407 |
| FTL | ferritin, light polypeptide | -0.197787 |
| TXNRD1 | thioredoxin reductase 1 | -0.184335 |
| TMSB10 | thymosin beta 10 | -0.109947 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0917229 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0751019 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0747198 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.074079 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0718085 |
| RPS6 | ribosomal protein S6 | -0.0671912 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0662927 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0648988 |
| RPLP1 | ribosomal protein, large, P1 | -0.0592794 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0577593 |
| FRY | furry homolog (Drosophila) | -0.0575645 |
| RPS19 | ribosomal protein S19 | -0.0537206 |
| RPL35A | ribosomal protein L35a | -0.0528796 |
| S100A6 | S100 calcium binding protein A6 | -0.0522687 |
| RPL23 | ribosomal protein L23 | -0.0512071 |
| PTMA | prothymosin, alpha | -0.0505676 |
| ACTN4 | actinin, alpha 4 | -0.0503728 |
| EZR | ezrin | -0.0502211 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0499115 |
| ANXA2 | annexin A2 | -0.0495211 |
| B2M | beta-2-microglobulin | -0.0479316 |
| RPLP2 | ribosomal protein, large, P2 | -0.0478881 |
| ZNF292 | zinc finger protein 292 | -0.0478578 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0470428 |
| ACTG1 | actin gamma 1 | -0.0459988 |
| TMC5 | transmembrane channel-like 5 | -0.0458381 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0449938 |
| PGK1 | phosphoglycerate kinase 1 | -0.0444173 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0437629 |
| RTN4 | reticulon 4 | -0.0432175 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0431145 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0428785 |
| JMJD1C | jumonji domain containing 1C | -0.0413278 |
| WASF2 | WAS protein family, member 2 | -0.0409768 |
| RPS21 | ribosomal protein S21 | -0.0402147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395831 |
| PTK2 | protein tyrosine kinase 2 | -0.0394789 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.039359 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0389542 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0384865 |
| NF1 | neurofibromin 1 | -0.0384245 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0382768 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0382214 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0379647 |
| KLF6 | Kruppel-like factor 6 | -0.0377299 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0376231 |
| EGR1 | early growth response 1 | -0.0372144 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0364927 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0357607 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0354008 |
| RPS13 | ribosomal protein S13 | -0.0350324 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0350249 |
| RPL34 | ribosomal protein L34 | -0.034748 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0346951 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0344405 |
| JUP | junction plakoglobin | -0.0341501 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0334423 |
| DST | dystonin | -0.0332249 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0329007 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0327947 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0327847 |
| GOLGA4 | golgin A4 | -0.0324444 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0322322 |
| SBF2 | SET binding factor 2 | -0.0314537 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0314458 |
| KRT17 | keratin 17, type I | -0.0314371 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310389 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0307182 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0303591 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0302586 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0302074 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030085 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0300356 |
| RBM39 | RNA binding motif protein 39 | -0.0298371 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298091 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0292668 |
| STK24 | serine/threonine kinase 24 | -0.0292249 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0288023 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0287601 |
| RPS11 | ribosomal protein S11 | -0.0286866 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0283454 |
| TMEM41B | transmembrane protein 41B | -0.0277292 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0276707 |
| CD2AP | CD2-associated protein | -0.0275318 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0275121 |
| RPL28 | ribosomal protein L28 | -0.0274512 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0273598 |
| LMNA | lamin A/C | -0.027235 |
| S100P | S100 calcium binding protein P | -0.0269294 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0267892 |
| CCNL1 | cyclin L1 | -0.0265951 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0264484 |
| CLDN4 | claudin 4 | -0.026357 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0263354 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0262396 |
| RPS16 | ribosomal protein S16 | -0.0261576 |
