| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.0794255 |
| INTS6 | integrator complex subunit 6 | 0.0716995 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0573379 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0523935 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0464175 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0447498 |
| JMJD1C | jumonji domain containing 1C | 0.0421578 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0403205 |
| HMGA2 | high mobility group AT-hook 2 | 0.0393122 |
| PTK2 | protein tyrosine kinase 2 | 0.0392441 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.038861 |
| MYOF | myoferlin | 0.0387419 |
| EFNA5 | ephrin-A5 | 0.0371463 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0351477 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0327731 |
| DSCAM | Down syndrome cell adhesion molecule | 0.032244 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0321126 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0319356 |
| ASPH | aspartate beta-hydroxylase | 0.0311694 |
| RBM39 | RNA binding motif protein 39 | 0.0302287 |
| RAI14 | retinoic acid induced 14 | 0.0299225 |
| NAV2 | neuron navigator 2 | 0.0295164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0291969 |
| AOPEP | aminopeptidase O (putative) | 0.0281028 |
| FNIP1 | folliculin interacting protein 1 | 0.0278872 |
| VCL | vinculin | 0.0277124 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0272857 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0271646 |
| IFI44L | interferon-induced protein 44-like | 0.0266083 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0264789 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.026209 |
| RIGI | RNA sensor RIG-I | 0.0259832 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0259268 |
| RASAL2 | RAS protein activator like 2 | 0.0256286 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0252202 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0251895 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0245977 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0244594 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0242516 |
| DST | dystonin | 0.024016 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0238046 |
| ATXN1 | ataxin 1 | 0.0237087 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0232195 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0229751 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0227545 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0226089 |
| SQSTM1 | sequestosome 1 | 0.0225556 |
| UTRN | utrophin | 0.0215565 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.021496 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0212119 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0211754 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0209814 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0207567 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0205105 |
| ANO6 | anoctamin 6 | 0.0201155 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0201124 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0199918 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0198078 |
| RNF220 | ring finger protein 220 | 0.0194307 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0191021 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0187116 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0185819 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0185705 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0184257 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0183707 |
| PLS3 | plastin 3 | 0.0182307 |
| UBAP2 | ubiquitin associated protein 2 | 0.0182194 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0180867 |
| TOP1 | topoisomerase (DNA) I | 0.0180601 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0180495 |
| PRKCA | protein kinase C, alpha | 0.0175603 |
| MTSS1 | metastasis suppressor 1 | 0.0174913 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0169268 |
| SMAD3 | SMAD family member 3 | 0.0168966 |
| SVIL | supervillin | 0.0168927 |
| SP100 | SP100 nuclear antigen | 0.0167539 |
| DGKH | diacylglycerol kinase, eta | 0.0164075 |
| HDAC9 | histone deacetylase 9 | 0.0162038 |
| IPO7 | importin 7 | 0.016157 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0161481 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0160943 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0160148 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0159707 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0157947 |
| FMNL2 | formin-like 2 | 0.0157927 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0157109 |
| GPHN | gephyrin | 0.0155912 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.015431 |
| CD44 | CD44 molecule (Indian blood group) | 0.0153451 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0152946 |
| MTAP | methylthioadenosine phosphorylase | 0.0152102 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0151804 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0150675 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.0148736 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0148064 |
| SIK3 | SIK family kinase 3 | 0.0147715 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0146959 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0146879 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0144277 |
| FOXO1 | forkhead box O1 | 0.014368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.172851 |
| NDRG1 | N-myc downstream regulated 1 | -0.127095 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.120176 |
| CLU | clusterin | -0.0870978 |
| LDHA | lactate dehydrogenase A | -0.0564877 |
| POTEF | POTE ankyrin domain family, member F | -0.0502874 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0496866 |
| B2M | beta-2-microglobulin | -0.0492613 |
| STC1 | stanniocalcin 1 | -0.0487747 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0486846 |
| MT2A | metallothionein 2A | -0.0459907 |
| PGK1 | phosphoglycerate kinase 1 | -0.0443511 |
| TMSB10 | thymosin beta 10 | -0.0441129 |
| ENO1 | enolase 1, (alpha) | -0.0403921 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.040127 |
| BCL2L1 | BCL2-like 1 | -0.0397197 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0376217 |
| MEF2A | myocyte enhancer factor 2A | -0.0365142 |
| SQLE | squalene epoxidase | -0.0344833 |
| RPS3 | ribosomal protein S3 | -0.0330951 |
| KRT17 | keratin 17, type I | -0.0330846 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0316083 |
| EPHA2 | EPH receptor A2 | -0.030757 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.030388 |
| FOSL1 | FOS-like antigen 1 | -0.0299369 |
| RPS6 | ribosomal protein S6 | -0.0297681 |
| RPS8 | ribosomal protein S8 | -0.0295346 |
| NRG1 | neuregulin 1 | -0.0290611 |
| ITGA6 | integrin, alpha 6 | -0.0285621 |
| RPL37 | ribosomal protein L37 | -0.0283565 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0282736 |
| EFHD2 | EF-hand domain family, member D2 | -0.0280025 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0272341 |
| IGF2 | insulin-like growth factor 2 | -0.0267726 |
| TGM2 | transglutaminase 2 | -0.0266137 |
| RPS17 | ribosomal protein S17 | -0.0266049 |
| PLEC | plectin | -0.0265626 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264691 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0264619 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0258955 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0254255 |
| RPS12 | ribosomal protein S12 | -0.0253991 |
| SULF1 | sulfatase 1 | -0.0247506 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0245031 |
| KISS1 | KiSS-1 metastasis-suppressor | -0.0242265 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0241267 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0240216 |
| LIMA1 | LIM domain and actin binding 1 | -0.0239976 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0238006 |
| CSNK1E | casein kinase 1, epsilon | -0.0237022 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0235299 |
| KRT6A | keratin 6A, type II | -0.0235055 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.023329 |
| OSMR | oncostatin M receptor | -0.0232977 |
| PODXL | podocalyxin-like | -0.0231968 |
| HLA-A | major histocompatibility complex, class I, A | -0.0231581 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.023018 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0227563 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0216438 |
| PFN1 | profilin 1 | -0.0214714 |
| TPM3 | tropomyosin 3 | -0.0213068 |
| TAGLN2 | transgelin 2 | -0.0211579 |
| RPL21 | ribosomal protein L21 | -0.0210979 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0209253 |
| SYNJ2 | synaptojanin 2 | -0.020861 |
| LAMA5 | laminin, alpha 5 | -0.0207076 |
| RPL9 | ribosomal protein L9 | -0.0206569 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0206506 |
| RPL31 | ribosomal protein L31 | -0.0205755 |
| DSG2 | desmoglein 2 | -0.0205705 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0204169 |
| S100A11 | S100 calcium binding protein A11 | -0.0202488 |
| ANXA11 | annexin A11 | -0.0201727 |
| RPS14 | ribosomal protein S14 | -0.0201218 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0200942 |
| WASF2 | WAS protein family, member 2 | -0.0200458 |
| S100A2 | S100 calcium binding protein A2 | -0.0198706 |
| S100A10 | S100 calcium binding protein A10 | -0.0197336 |
| RPS5 | ribosomal protein S5 | -0.0195391 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.019389 |
| PLAT | plasminogen activator, tissue | -0.0192365 |
| HMGA1 | high mobility group AT-hook 1 | -0.0187307 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0187244 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0186152 |
| RPS2 | ribosomal protein S2 | -0.0185961 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0185119 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0184934 |
| TMSB4X | thymosin beta 4, X-linked | -0.018341 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0181538 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0180415 |
| THOC2 | THO complex 2 | -0.0180128 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0176686 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0175436 |
| CD59 | CD59 molecule, complement regulatory protein | -0.017523 |
| RACK1 | receptor for activated C kinase 1 | -0.0174147 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.017217 |
| KRT14 | keratin 14, type I | -0.0172056 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0164203 |
| RPS27 | ribosomal protein S27 | -0.0163096 |
| YBX1 | Y box binding protein 1 | -0.0162162 |