| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.164502 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.141314 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.128564 |
| NAV2 | neuron navigator 2 | 0.123441 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108981 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.102532 |
| ASPH | aspartate beta-hydroxylase | 0.102356 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0867139 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0863088 |
| INTS6 | integrator complex subunit 6 | 0.0859686 |
| TLE4 | transducin-like enhancer of split 4 | 0.0831361 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0771216 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0681525 |
| ENO1 | enolase 1, (alpha) | 0.0674814 |
| SET | SET nuclear proto-oncogene | 0.0649969 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0624082 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0615565 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.061518 |
| UBC | ubiquitin C | 0.0612623 |
| SMAD3 | SMAD family member 3 | 0.0604691 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0572602 |
| PKM | pyruvate kinase, muscle | 0.0560834 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0557741 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0556822 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0553349 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0548878 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0548393 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0545519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0536699 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0523222 |
| CANX | calnexin | 0.0503833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0488529 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0488416 |
| SQSTM1 | sequestosome 1 | 0.0478019 |
| RIGI | RNA sensor RIG-I | 0.0471382 |
| PRELID2 | PRELI domain containing 2 | 0.0470064 |
| PCBP2 | poly(rC) binding protein 2 | 0.0458544 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0456766 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0454859 |
| MYOF | myoferlin | 0.0454817 |
| PLSCR1 | phospholipid scramblase 1 | 0.0449885 |
| ERBIN | erbb2 interacting protein | 0.0447404 |
| BBX | bobby sox homolog (Drosophila) | 0.0443147 |
| FLNA | filamin A, alpha | 0.0431145 |
| FN1 | fibronectin 1 | 0.0430386 |
| VCL | vinculin | 0.0421291 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0418483 |
| RAD51B | RAD51 paralog B | 0.0416418 |
| ATXN1 | ataxin 1 | 0.0413595 |
| FNIP1 | folliculin interacting protein 1 | 0.0411209 |
| POTEF | POTE ankyrin domain family, member F | 0.0406656 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0402419 |
| RND3 | Rho family GTPase 3 | 0.0400944 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0400696 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0399422 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0397808 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0393652 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0390579 |
| SEPTIN9 | septin 9 | 0.0389794 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0386824 |
| DST | dystonin | 0.0386363 |
| WWOX | WW domain containing oxidoreductase | 0.0386347 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0382817 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0382559 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0380437 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0377351 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0374745 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0374521 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0374383 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0373736 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0367844 |
| CLIC4 | chloride intracellular channel 4 | 0.0365424 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0363241 |
| RNF213 | ring finger protein 213 | 0.0362302 |
| LDHA | lactate dehydrogenase A | 0.0362259 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0360262 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0358324 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0356167 |
| MED13L | mediator complex subunit 13-like | 0.0355274 |
| DTNA | dystrobrevin, alpha | 0.0355161 |
| MYO10 | myosin X | 0.0353289 |
| RUNX1 | runt-related transcription factor 1 | 0.0343904 |
| MSN | moesin | 0.0343364 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0340615 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0340344 |
| TPM3 | tropomyosin 3 | 0.0339735 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0338699 |
| FHIT | fragile histidine triad | 0.0338616 |
| SMYD3 | SET and MYND domain containing 3 | 0.0336953 |
| UTRN | utrophin | 0.0336557 |
| EFNA5 | ephrin-A5 | 0.0335755 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0334398 |
| UBAP2 | ubiquitin associated protein 2 | 0.0333197 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0331619 |
| PRKCA | protein kinase C, alpha | 0.0330716 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0329931 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0328766 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0322955 |
| DIPK2A | divergent protein kinase domain 2A | 0.0321846 |
| TUFT1 | tuftelin 1 | 0.0317741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.164169 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.159721 |
| HLA-B | major histocompatibility complex, class I, B | -0.108344 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.101661 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0994897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.080832 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0794311 |
| GLIS3 | GLIS family zinc finger 3 | -0.0756782 |
| OSMR | oncostatin M receptor | -0.0747446 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0675138 |
| TXNRD1 | thioredoxin reductase 1 | -0.0649814 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0595418 |
| ATP13A3 | ATPase type 13A3 | -0.05911 |
| HLA-C | major histocompatibility complex, class I, C | -0.0538017 |
| TUBB | tubulin, beta class I | -0.052074 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.05184 |
| MT1X | metallothionein 1X | -0.0509434 |
| MT2A | metallothionein 2A | -0.0492683 |
| POSTN | periostin, osteoblast specific factor | -0.0492156 |
| FTL | ferritin, light polypeptide | -0.0492034 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0476858 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0458812 |
| CD44 | CD44 molecule (Indian blood group) | -0.0442675 |
| TGFB2 | transforming growth factor, beta 2 | -0.0439806 |
| TMSB10 | thymosin beta 10 | -0.0434918 |
| MAP1B | microtubule-associated protein 1B | -0.042696 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.041125 |
| RPS6 | ribosomal protein S6 | -0.0404693 |
| RPL35A | ribosomal protein L35a | -0.0392256 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0386161 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0380658 |
| ACTG1 | actin gamma 1 | -0.0374618 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0356336 |
| MKI67 | marker of proliferation Ki-67 | -0.0342857 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0337204 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0324553 |
| GOLGA3 | golgin A3 | -0.0314445 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301077 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0295884 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0291855 |
| PGK1 | phosphoglycerate kinase 1 | -0.0288909 |
| SCFD2 | sec1 family domain containing 2 | -0.0288489 |
| RPL12 | ribosomal protein L12 | -0.0286952 |
| ARF4 | ADP-ribosylation factor 4 | -0.0284539 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | -0.0278937 |
| TRIM56 | tripartite motif containing 56 | -0.0275224 |
| LOX | lysyl oxidase | -0.0266556 |
| RPS19 | ribosomal protein S19 | -0.0264928 |
| TMEM41B | transmembrane protein 41B | -0.0264824 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.026348 |
| GPR107 | G protein-coupled receptor 107 | -0.0262936 |
| FOXP1 | forkhead box P1 | -0.0260869 |
| ARF1 | ADP-ribosylation factor 1 | -0.025038 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.024908 |
| GOLGA2 | golgin A2 | -0.0246796 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0239624 |
| PLCB4 | phospholipase C, beta 4 | -0.02384 |
| UFM1 | ubiquitin-fold modifier 1 | -0.023804 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0235568 |
| GRAMD2B | GRAM domain containing 2B | -0.0231642 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.022838 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0226472 |
| RPLP2 | ribosomal protein, large, P2 | -0.0225205 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0224094 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0223988 |
| TMSB4X | thymosin beta 4, X-linked | -0.0221726 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0219126 |
| MAP4 | microtubule-associated protein 4 | -0.0219019 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0218824 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0217219 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0216692 |
| NPPB | natriuretic peptide B | -0.0214878 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0213397 |
| KLF6 | Kruppel-like factor 6 | -0.0212612 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0211531 |
| GOLT1B | golgi transport 1B | -0.0209943 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0208282 |
| PTX3 | pentraxin 3, long | -0.0206244 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0204543 |
| ZXDC | ZXD family zinc finger C | -0.020391 |
| CTSD | cathepsin D | -0.0202559 |
| NUP214 | nucleoporin 214kDa | -0.0202139 |
| RAB2A | RAB2A, member RAS oncogene family | -0.020026 |
| MGLL | monoglyceride lipase | -0.0199827 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0199155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0197245 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0195231 |
| HM13 | histocompatibility (minor) 13 | -0.0192905 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0192524 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0191044 |
| RPLP1 | ribosomal protein, large, P1 | -0.0188436 |
| RPL35 | ribosomal protein L35 | -0.0187345 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0186572 |
| FSTL1 | follistatin-like 1 | -0.0185234 |
| RPL26 | ribosomal protein L26 | -0.0184664 |
| SERF2 | small EDRK-rich factor 2 | -0.0184071 |
| MYL12B | myosin, light chain 12B, regulatory | -0.018121 |
| HLA-A | major histocompatibility complex, class I, A | -0.0180905 |
| BSG | basigin (Ok blood group) | -0.0180034 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0177734 |