| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.30409 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.165426 |
| GOLGA4 | golgin A4 | 0.0901459 |
| PTMA | prothymosin, alpha | 0.0751854 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0694372 |
| CALR | calreticulin | 0.059647 |
| RNF145 | ring finger protein 145 | 0.0572319 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0535579 |
| FAM13A | family with sequence similarity 13, member A | 0.0533011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0487542 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0484568 |
| FNDC3B | fibronectin type III domain containing 3B | 0.040809 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0398641 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0385252 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0382918 |
| CENPF | centromere protein F, 350/400kDa | 0.0381018 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0378076 |
| OGA | O-GlcNAcase | 0.0378011 |
| COPA | coatomer protein complex, subunit alpha | 0.0376731 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.037666 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0371439 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0368356 |
| ZNF292 | zinc finger protein 292 | 0.0365705 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0351054 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0345162 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0340613 |
| MED13L | mediator complex subunit 13-like | 0.0340586 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0330781 |
| CANX | calnexin | 0.0327217 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0316491 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0314387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0304786 |
| NEBL | nebulette | 0.030334 |
| NUCB2 | nucleobindin 2 | 0.030196 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0296543 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0293455 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291734 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0287271 |
| TFG | TRK-fused gene | 0.0280286 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0279042 |
| EREG | epiregulin | 0.0278329 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0277751 |
| SEC24D | SEC24 family member D | 0.0277522 |
| RBM39 | RNA binding motif protein 39 | 0.0276578 |
| PCM1 | pericentriolar material 1 | 0.0273471 |
| SRP54 | signal recognition particle 54kDa | 0.0265304 |
| PTEN | phosphatase and tensin homolog | 0.0263217 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0262277 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0261531 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0260267 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0256541 |
| HELZ | helicase with zinc finger | 0.0255869 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0254653 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0252133 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.025118 |
| EXOC1 | exocyst complex component 1 | 0.024975 |
| TMF1 | TATA element modulatory factor 1 | 0.02492 |
| GOLGB1 | golgin B1 | 0.0248395 |
| SETD5 | SET domain containing 5 | 0.0238082 |
| NUP58 | nucleoporin 58 | 0.0237126 |
| VEGFA | vascular endothelial growth factor A | 0.0236447 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0236348 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0234355 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0232959 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0232536 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0232307 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.023213 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0231317 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0230165 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0229431 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0229175 |
| SUCO | SUN domain containing ossification factor | 0.0228529 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0227543 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0227527 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0227343 |
| NEK7 | NIMA-related kinase 7 | 0.0227 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.022655 |
| MED13 | mediator complex subunit 13 | 0.0222925 |
| NBAS | neuroblastoma amplified sequence | 0.022198 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0219814 |
| TXNIP | thioredoxin interacting protein | 0.0219631 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0219303 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0217829 |
| EHF | ets homologous factor | 0.0217755 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0215672 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0211601 |
| USP3 | ubiquitin specific peptidase 3 | 0.0210216 |
| USP6NL | USP6 N-terminal like | 0.0209315 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0208687 |
| WDR45B | WD repeat domain 45B | 0.0204811 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0204769 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0204215 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.020275 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0201864 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0201532 |
| TPR | translocated promoter region, nuclear basket protein | 0.0200759 |
| ZNF654 | zinc finger protein 654 | 0.0200031 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0199741 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0197867 |
| RREB1 | ras responsive element binding protein 1 | 0.0197817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.265714 |
| NPSR1 | neuropeptide S receptor 1 | -0.173974 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.162541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.148947 |
| S100A6 | S100 calcium binding protein A6 | -0.119423 |
| ACTG1 | actin gamma 1 | -0.116634 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.115201 |
| VCL | vinculin | -0.099644 |
| FLNB | filamin B, beta | -0.0788268 |
| TPM4 | tropomyosin 4 | -0.07791 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0743276 |
| MYO1E | myosin IE | -0.0722114 |
| ANXA2 | annexin A2 | -0.0703169 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0678326 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0649443 |
| SLC35F3 | solute carrier family 35, member F3 | -0.062573 |
| AHNAK | AHNAK nucleoprotein | -0.0625028 |
| ONECUT3 | one cut homeobox 3 | -0.0614969 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0613729 |
| ACTN4 | actinin, alpha 4 | -0.0588987 |
| KLF6 | Kruppel-like factor 6 | -0.0564421 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0557858 |
| FTL | ferritin, light polypeptide | -0.0534665 |
| HMGA1 | high mobility group AT-hook 1 | -0.052048 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.051618 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0515654 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0514754 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0511979 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0506153 |
| PIGR | polymeric immunoglobulin receptor | -0.0473926 |
| RPL35A | ribosomal protein L35a | -0.046649 |
| LAMC2 | laminin, gamma 2 | -0.0464031 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0449178 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0447046 |
| SMYD3 | SET and MYND domain containing 3 | -0.0446425 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0445738 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0444591 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.044034 |
| RPL26 | ribosomal protein L26 | -0.0437162 |
| FRMD5 | FERM domain containing 5 | -0.0435399 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0432777 |
| PDLIM5 | PDZ and LIM domain 5 | -0.043007 |
| S100A10 | S100 calcium binding protein A10 | -0.0424497 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0416797 |
| IER3 | immediate early response 3 | -0.0414979 |
| RPS19 | ribosomal protein S19 | -0.0414167 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0411439 |
| RPL31 | ribosomal protein L31 | -0.0400165 |
| ASPH | aspartate beta-hydroxylase | -0.0399127 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0396192 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0374729 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0372905 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0372646 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0368599 |
| KRT19 | keratin 19, type I | -0.0366796 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0364456 |
| SVIL | supervillin | -0.0363222 |
| RPL34 | ribosomal protein L34 | -0.0359751 |
| EZR | ezrin | -0.0355205 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0344269 |
| AREG | amphiregulin | -0.0343177 |
| ANXA3 | annexin A3 | -0.0339129 |
| RPL9 | ribosomal protein L9 | -0.0336744 |
| POTEF | POTE ankyrin domain family, member F | -0.0336319 |
| OCIAD2 | OCIA domain containing 2 | -0.0334436 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0333066 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0329873 |
| RPS12 | ribosomal protein S12 | -0.0329237 |
| CCND1 | cyclin D1 | -0.0329132 |
| KLK10 | kallikrein-related peptidase 10 | -0.0327295 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0324079 |
| LAMB3 | laminin, beta 3 | -0.0319505 |
| RPLP2 | ribosomal protein, large, P2 | -0.0318009 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0315276 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.031395 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0310546 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0308621 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0307952 |
| FHIT | fragile histidine triad | -0.0306627 |
| MTAP | methylthioadenosine phosphorylase | -0.0304296 |
| RPS3 | ribosomal protein S3 | -0.0301012 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0294321 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0290475 |
| PALLD | palladin, cytoskeletal associated protein | -0.0289413 |
| S100A11 | S100 calcium binding protein A11 | -0.0288605 |
| MUC17 | mucin 17, cell surface associated | -0.0288074 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.028721 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0286492 |
| KRT8 | keratin 8, type II | -0.0284786 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0282494 |
| RPL23 | ribosomal protein L23 | -0.0282381 |
| EGR1 | early growth response 1 | -0.0281821 |
| TFF1 | trefoil factor 1 | -0.0281632 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0278832 |
| PERP | PERP, TP53 apoptosis effector | -0.027761 |
| RPS24 | ribosomal protein S24 | -0.0277049 |
| RPL37A | ribosomal protein L37a | -0.0268852 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0265008 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0264376 |
| SH3D19 | SH3 domain containing 19 | -0.0261348 |
