| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vinblastine (sulfate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.136108 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0889794 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0686366 |
| CADM2 | cell adhesion molecule 2 | 0.0667092 |
| DST | dystonin | 0.0633277 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0606714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0501821 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0482643 |
| PRELID2 | PRELI domain containing 2 | 0.0449419 |
| RAD51B | RAD51 paralog B | 0.040148 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0391374 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0388409 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0380169 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0350777 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0341043 |
| SETX | senataxin | 0.033239 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0327261 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0318835 |
| CANX | calnexin | 0.0317718 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.030537 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.030392 |
| ENO1 | enolase 1, (alpha) | 0.030163 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0299061 |
| EMP1 | epithelial membrane protein 1 | 0.0295686 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0292747 |
| SP100 | SP100 nuclear antigen | 0.0281671 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0279599 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0272026 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0270183 |
| EXOC4 | exocyst complex component 4 | 0.025248 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0250965 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0250226 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0248727 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0232805 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0226933 |
| PLSCR1 | phospholipid scramblase 1 | 0.0224163 |
| CD44 | CD44 molecule (Indian blood group) | 0.021687 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0213902 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0213632 |
| RIGI | RNA sensor RIG-I | 0.021191 |
| MB21D2 | Mab-21 domain containing 2 | 0.0211393 |
| PMP22 | peripheral myelin protein 22 | 0.0209876 |
| WWOX | WW domain containing oxidoreductase | 0.0208212 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0204782 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0203632 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0202719 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0202076 |
| SMYD3 | SET and MYND domain containing 3 | 0.0200957 |
| CALR | calreticulin | 0.0199066 |
| FERMT1 | fermitin family member 1 | 0.0197932 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0196661 |
| BPTF | bromodomain PHD finger transcription factor | 0.0195761 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0195035 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0194626 |
| HLA-B | major histocompatibility complex, class I, B | 0.0194218 |
| HM13 | histocompatibility (minor) 13 | 0.0190898 |
| CEP128 | centrosomal protein 128kDa | 0.0189892 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.018671 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0186441 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0186009 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0185848 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0178491 |
| SMC4 | structural maintenance of chromosomes 4 | 0.017405 |
| TGM2 | transglutaminase 2 | 0.0172963 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0172797 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0172546 |
| PDE10A | phosphodiesterase 10A | 0.0164406 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0161632 |
| ATM | ATM serine/threonine kinase | 0.0161202 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0161172 |
| VCL | vinculin | 0.0160834 |
| CCDC190 | coiled-coil domain containing 190 | 0.0159156 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0158419 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0156438 |
| DIAPH3 | diaphanous-related formin 3 | 0.0155646 |
| SVIL | supervillin | 0.0154239 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0152659 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0151996 |
| WDR27 | WD repeat domain 27 | 0.0151251 |
| GOLGB1 | golgin B1 | 0.0150639 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.015001 |
| RGS4 | regulator of G-protein signaling 4 | 0.0149808 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0149782 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.014899 |
| RRM2 | ribonucleotide reductase M2 | 0.0148528 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0147584 |
| CCDC18 | coiled-coil domain containing 18 | 0.014708 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0145543 |
| PRKCE | protein kinase C, epsilon | 0.0144859 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0143592 |
| HELLS | helicase, lymphoid-specific | 0.0142504 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0142119 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0141955 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0141476 |
| INTS6 | integrator complex subunit 6 | 0.0140061 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0138483 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.013731 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0136151 |
| RSPH3 | radial spoke 3 homolog (Chlamydomonas) | 0.0136097 |
| KRT18 | keratin 18, type I | 0.0134141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253273 |
| TMSB10 | thymosin beta 10 | -0.198304 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.134842 |
| MT2A | metallothionein 2A | -0.11054 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0936044 |
| RAI1 | retinoic acid induced 1 | -0.0913388 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0864138 |
| APP | amyloid beta (A4) precursor protein | -0.0848802 |
| TMSB4X | thymosin beta 4, X-linked | -0.0700492 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0666346 |
| MT1X | metallothionein 1X | -0.0664291 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.06467 |
| RPL23 | ribosomal protein L23 | -0.0641489 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0640924 |
| FTL | ferritin, light polypeptide | -0.0615422 |
| FMNL2 | formin-like 2 | -0.061347 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0597915 |
| RPL35A | ribosomal protein L35a | -0.0568064 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0563393 |
| PTMA | prothymosin, alpha | -0.0560169 |
| CAPRIN2 | caprin family member 2 | -0.0541589 |
| EZR | ezrin | -0.0519916 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0519818 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0517909 |
| TXNIP | thioredoxin interacting protein | -0.0515589 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0511048 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0508383 |
| RAB27B | RAB27B, member RAS oncogene family | -0.050737 |
| AHNAK | AHNAK nucleoprotein | -0.0501085 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0494092 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0493194 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0487426 |
| TXNRD1 | thioredoxin reductase 1 | -0.0484069 |
| RPL12 | ribosomal protein L12 | -0.0483305 |
| PTK2 | protein tyrosine kinase 2 | -0.0480307 |
| SRPK2 | SRSF protein kinase 2 | -0.0475331 |
| ZNF292 | zinc finger protein 292 | -0.0469061 |
| KLF6 | Kruppel-like factor 6 | -0.0461833 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0461695 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0457137 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0443194 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0442148 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043602 |
| RPS19 | ribosomal protein S19 | -0.0432829 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.043056 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0428212 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0422194 |
| SPAG9 | sperm associated antigen 9 | -0.0414685 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0414101 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0412626 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0408389 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0407034 |
| SBF2 | SET binding factor 2 | -0.0402608 |
| RLF | rearranged L-myc fusion | -0.0401098 |
| RBM39 | RNA binding motif protein 39 | -0.0398591 |
| USP36 | ubiquitin specific peptidase 36 | -0.039694 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0391945 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0391728 |
| EHBP1 | EH domain binding protein 1 | -0.0382742 |
| EREG | epiregulin | -0.0379574 |
| RPL26 | ribosomal protein L26 | -0.0378486 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0367289 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0366503 |
| TOP1 | topoisomerase (DNA) I | -0.0361276 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | -0.0359382 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0356735 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0351751 |
| PGK1 | phosphoglycerate kinase 1 | -0.0349631 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0346612 |
| POTEF | POTE ankyrin domain family, member F | -0.0344338 |
| CCNL1 | cyclin L1 | -0.034324 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0342477 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0342353 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0340948 |
| RPS24 | ribosomal protein S24 | -0.0339385 |
| WDR45B | WD repeat domain 45B | -0.0339032 |
| RPS23 | ribosomal protein S23 | -0.0338133 |
| ANXA1 | annexin A1 | -0.0337504 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.03373 |
| MATR3 | matrin 3 | -0.0334108 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0333621 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0324563 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0323367 |
| RNF145 | ring finger protein 145 | -0.0311448 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.030676 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0306414 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0305323 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0303969 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0302385 |
| RTN4 | reticulon 4 | -0.0302252 |
| YBX3 | Y box binding protein 3 | -0.0301784 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0300552 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0299748 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0298445 |
| OGA | O-GlcNAcase | -0.029666 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.029358 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.029221 |
| RPS21 | ribosomal protein S21 | -0.0291284 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.028833 |
| ACTG1 | actin gamma 1 | -0.0282565 |
