| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.083238 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0774468 |
| FMNL2 | formin-like 2 | 0.0747477 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.070819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.065111 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0644976 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0635656 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.062196 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0614627 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0600416 |
| RBM25 | RNA binding motif protein 25 | 0.0567847 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0559135 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.055839 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0557519 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0544758 |
| FTL | ferritin, light polypeptide | 0.0475877 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.046071 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0453565 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0447695 |
| EGFR | epidermal growth factor receptor | 0.0441112 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0439106 |
| COPA | coatomer protein complex, subunit alpha | 0.0436722 |
| MCL1 | myeloid cell leukemia 1 | 0.0411811 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0406981 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0405685 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0395237 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0390446 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0386423 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0384515 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0381536 |
| RBM39 | RNA binding motif protein 39 | 0.0377743 |
| TFG | TRK-fused gene | 0.0374294 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0372786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0372143 |
| IL6 | interleukin 6 | 0.036569 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0364967 |
| VIM | vimentin | 0.0362217 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0357709 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0352593 |
| BRD2 | bromodomain containing 2 | 0.0351966 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0342878 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0341919 |
| POTEF | POTE ankyrin domain family, member F | 0.0340862 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0340089 |
| STC1 | stanniocalcin 1 | 0.0337251 |
| ZNF207 | zinc finger protein 207 | 0.033653 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0334301 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0326896 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0324381 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0320142 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0308673 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030485 |
| PARD3 | par-3 family cell polarity regulator | 0.0299142 |
| CCNY | cyclin Y | 0.029416 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0292778 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0291826 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0287963 |
| ERBIN | erbb2 interacting protein | 0.0285777 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0283915 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0283832 |
| NEBL | nebulette | 0.028275 |
| B2M | beta-2-microglobulin | 0.0280563 |
| CALR | calreticulin | 0.0275617 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0275494 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0275482 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0275477 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0273839 |
| HELZ | helicase with zinc finger | 0.0273139 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0272352 |
| RNF145 | ring finger protein 145 | 0.027073 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0270341 |
| TPM3 | tropomyosin 3 | 0.0266553 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263383 |
| MYO1E | myosin IE | 0.0263115 |
| SIK3 | SIK family kinase 3 | 0.0262186 |
| SLMAP | sarcolemma associated protein | 0.0259363 |
| HLA-B | major histocompatibility complex, class I, B | 0.0258028 |
| MRTFA | myocardin related transcription factor A | 0.0257706 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.025708 |
| LDHA | lactate dehydrogenase A | 0.0256149 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0255055 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0254515 |
| PCBP2 | poly(rC) binding protein 2 | 0.0252138 |
| DOCK5 | dedicator of cytokinesis 5 | 0.024758 |
| FOXO3 | forkhead box O3 | 0.0245244 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0244066 |
| CALD1 | caldesmon 1 | 0.0242392 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0240446 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0240283 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0239152 |
| CCNL1 | cyclin L1 | 0.0238018 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0237587 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0235931 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0235209 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0235082 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0233018 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0232092 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0231997 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0231981 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0230753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | -0.179799 |
| TXNRD1 | thioredoxin reductase 1 | -0.174969 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.170954 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.165142 |
| MT2A | metallothionein 2A | -0.131131 |
| TMSB10 | thymosin beta 10 | -0.12631 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0726384 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0652871 |
| RPL23 | ribosomal protein L23 | -0.063214 |
| AHNAK | AHNAK nucleoprotein | -0.0559041 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0533765 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.053346 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0515125 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0469622 |
| TUBB | tubulin, beta class I | -0.0464899 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0455926 |
| RPL4 | ribosomal protein L4 | -0.0446932 |
| KLF6 | Kruppel-like factor 6 | -0.0442445 |
| OSMR | oncostatin M receptor | -0.0408089 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0390342 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0374509 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.033695 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0335708 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0335486 |
| RPS21 | ribosomal protein S21 | -0.0334262 |
| ASPH | aspartate beta-hydroxylase | -0.0330613 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0330501 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0323745 |
| DST | dystonin | -0.0317234 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0315856 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0305723 |
| TUBA1B | tubulin, alpha 1b | -0.0304343 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0297968 |
| RPLP1 | ribosomal protein, large, P1 | -0.029417 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0292303 |
| RPL19 | ribosomal protein L19 | -0.0289662 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0288493 |
| PFDN2 | prefoldin subunit 2 | -0.0288017 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0287608 |
| RTN4 | reticulon 4 | -0.0287169 |
| RPS19 | ribosomal protein S19 | -0.0276114 |
| RPL8 | ribosomal protein L8 | -0.027054 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0264853 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0261827 |
| AK1 | adenylate kinase 1 | -0.0260604 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.02463 |
| RPL26 | ribosomal protein L26 | -0.0245394 |
| NAV3 | neuron navigator 3 | -0.0245319 |
| RPS27 | ribosomal protein S27 | -0.0232575 |
| PLEC | plectin | -0.0220422 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0209988 |
| IGF2 | insulin-like growth factor 2 | -0.0209261 |
| RPL3 | ribosomal protein L3 | -0.0208555 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0208209 |
| TMEM117 | transmembrane protein 117 | -0.0204758 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0204332 |
| RPS12 | ribosomal protein S12 | -0.0202737 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0200356 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.019984 |
| RACK1 | receptor for activated C kinase 1 | -0.0198751 |
| BICC1 | BicC family RNA binding protein 1 | -0.019338 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0191695 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0190047 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0189799 |
| RPL32 | ribosomal protein L32 | -0.018951 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0188606 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.018403 |
| MAP1B | microtubule-associated protein 1B | -0.0183359 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0181802 |
| FGB | fibrinogen beta chain | -0.0180068 |
| GLIS3 | GLIS family zinc finger 3 | -0.0179679 |
| DSE | dermatan sulfate epimerase | -0.017537 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0173194 |
| PARK7 | parkinson protein 7 | -0.0171493 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0170429 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0170153 |
| HDLBP | high density lipoprotein binding protein | -0.0170097 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0169456 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0166844 |
| PFKP | phosphofructokinase, platelet | -0.0164318 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0164036 |
| RPL12 | ribosomal protein L12 | -0.0163032 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.016227 |
| YME1L1 | YME1-like 1 ATPase | -0.0161934 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0161701 |
| HMOX1 | heme oxygenase 1 | -0.0160673 |
| HDAC9 | histone deacetylase 9 | -0.0159514 |
| S100A9 | S100 calcium binding protein A9 | -0.0158791 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0157773 |
| RPS17 | ribosomal protein S17 | -0.0156772 |
| LAMB1 | laminin, beta 1 | -0.0155221 |
| STEAP1B | STEAP family member 1B | -0.0150871 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0150739 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0148986 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0148883 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0147382 |
| RPL30 | ribosomal protein L30 | -0.0147163 |
| ATF4 | activating transcription factor 4 | -0.0146599 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0144972 |
| RPLP0 | ribosomal protein, large, P0 | -0.0144296 |
