| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0963139 |
| FAM13A | family with sequence similarity 13, member A | 0.0875165 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0798164 |
| PRKCA | protein kinase C, alpha | 0.0751361 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0724755 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0691068 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0668415 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0662883 |
| SMAD3 | SMAD family member 3 | 0.0658896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0646982 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0642365 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0629843 |
| JMJD1C | jumonji domain containing 1C | 0.0617772 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0616601 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0597519 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0588713 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0586127 |
| USP34 | ubiquitin specific peptidase 34 | 0.0581927 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0571404 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0539738 |
| MYOF | myoferlin | 0.0528934 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0517548 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0515707 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0511763 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0499354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0493382 |
| ACTN4 | actinin, alpha 4 | 0.0479602 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0478982 |
| CDC73 | cell division cycle 73 | 0.0471077 |
| FLNB | filamin B, beta | 0.0464445 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0457703 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0452933 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0450523 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0448487 |
| ATXN1 | ataxin 1 | 0.0441214 |
| EFNA5 | ephrin-A5 | 0.0440962 |
| FMNL2 | formin-like 2 | 0.0428259 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0423697 |
| RBM39 | RNA binding motif protein 39 | 0.0420136 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0417852 |
| SBF2 | SET binding factor 2 | 0.0417149 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0416809 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0414123 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0413817 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0409137 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0405939 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0395442 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0395188 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0394996 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0392165 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0381958 |
| FN1 | fibronectin 1 | 0.0381718 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0380796 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0377909 |
| MYO10 | myosin X | 0.0375722 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0372936 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0372607 |
| SEC24D | SEC24 family member D | 0.0365939 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0365302 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0360276 |
| MED13 | mediator complex subunit 13 | 0.0359957 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0359407 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0353599 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0340254 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0339558 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0338744 |
| NAV2 | neuron navigator 2 | 0.0337787 |
| CLINT1 | clathrin interactor 1 | 0.0333886 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0333183 |
| FMN1 | formin 1 | 0.0329092 |
| HELZ | helicase with zinc finger | 0.0328431 |
| DST | dystonin | 0.0327829 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0323629 |
| RBM33 | RNA binding motif protein 33 | 0.0319017 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0318674 |
| FLNA | filamin A, alpha | 0.0317069 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0315903 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0314534 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.031391 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0313777 |
| HDLBP | high density lipoprotein binding protein | 0.0313667 |
| TJP1 | tight junction protein 1 | 0.0313541 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0312227 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0307132 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0306786 |
| NUP98 | nucleoporin 98kDa | 0.0304459 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0302894 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0302214 |
| FRYL | FRY-like | 0.0300383 |
| TES | testin LIM domain protein | 0.0297143 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0294628 |
| GNAS | GNAS complex locus | 0.0287469 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0287355 |
| BBX | bobby sox homolog (Drosophila) | 0.0283562 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0282518 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0282445 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.028214 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0281416 |
| RRBP1 | ribosome binding protein 1 | 0.0280861 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0279842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.128033 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119337 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0829418 |
| LMO7 | LIM domain 7 | -0.0815876 |
| TMSB10 | thymosin beta 10 | -0.0718281 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0688162 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0657481 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0628751 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.061345 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0605713 |
| KRT17 | keratin 17, type I | -0.0573089 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0564586 |
| FTL | ferritin, light polypeptide | -0.0506352 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0499178 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.049272 |
| POTEF | POTE ankyrin domain family, member F | -0.0485011 |
| SPAG9 | sperm associated antigen 9 | -0.048286 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0475994 |
| RPL19 | ribosomal protein L19 | -0.0469563 |
| PERP | PERP, TP53 apoptosis effector | -0.0437886 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0431951 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0427394 |
| STC1 | stanniocalcin 1 | -0.0425168 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0424447 |
| ENO1 | enolase 1, (alpha) | -0.0418331 |
| RNF149 | ring finger protein 149 | -0.0414692 |
| S100A6 | S100 calcium binding protein A6 | -0.0409143 |
| RTN4 | reticulon 4 | -0.0403271 |
| PTMA | prothymosin, alpha | -0.038734 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0387013 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.038389 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0368916 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0362881 |
| SYT1 | synaptotagmin I | -0.0357318 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0349124 |
| RPL12 | ribosomal protein L12 | -0.0347926 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0343459 |
| RPL35A | ribosomal protein L35a | -0.034223 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0340622 |
| RIGI | RNA sensor RIG-I | -0.0339145 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0338776 |
| RPS19 | ribosomal protein S19 | -0.0336207 |
| MUC16 | mucin 16, cell surface associated | -0.033 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0325952 |
| STK17A | serine/threonine kinase 17a | -0.0320692 |
| JUP | junction plakoglobin | -0.0320552 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0319043 |
| FHIT | fragile histidine triad | -0.0318908 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0318349 |
| TMEM41B | transmembrane protein 41B | -0.0318246 |
| RPL15 | ribosomal protein L15 | -0.031824 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0318223 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.031315 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.031269 |
| NRG1 | neuregulin 1 | -0.0304456 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0304108 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0301726 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0300032 |
| ACTG1 | actin gamma 1 | -0.0299898 |
| RPL37 | ribosomal protein L37 | -0.0296726 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0296145 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0295238 |
| EXOC4 | exocyst complex component 4 | -0.0294573 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0291122 |
| H1-0 | H1.0 linker histone | -0.0290791 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290497 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0287841 |
| WWC1 | WW and C2 domain containing 1 | -0.0286587 |
| SEPTIN2 | septin 2 | -0.0286282 |
| RPS6 | ribosomal protein S6 | -0.0283338 |
| KLF6 | Kruppel-like factor 6 | -0.0282038 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0281769 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0280297 |
| RPL36 | ribosomal protein L36 | -0.0279396 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0278072 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.027727 |
| BRD4 | bromodomain containing 4 | -0.0271978 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0271185 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027057 |
| KIAA1217 | KIAA1217 | -0.0270015 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0268324 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0267292 |
| TXNRD1 | thioredoxin reductase 1 | -0.0265758 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0265335 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0264728 |
| MED13L | mediator complex subunit 13-like | -0.0261754 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0260741 |
| DIAPH1 | diaphanous-related formin 1 | -0.0256944 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0256629 |
| HMGA1 | high mobility group AT-hook 1 | -0.0256537 |
| ATP11B | ATPase, class VI, type 11B | -0.0255696 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255482 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0254272 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0253831 |
| RPL26 | ribosomal protein L26 | -0.0251389 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0251036 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0250892 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0250335 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0248892 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0247759 |