Vinblastine (sulfate)_Panc 03.27 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Vinblastine (sulfate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Vinblastine (sulfate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0759239
TRIO trio Rho guanine nucleotide exchange factor 0.0707823
SAMD4A sterile alpha motif domain containing 4A 0.0632555
TSC22D2 TSC22 domain family, member 2 0.0622505
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0585268
PTMA prothymosin, alpha 0.0574045
FNDC3B fibronectin type III domain containing 3B 0.0550824
ARHGAP29 Rho GTPase activating protein 29 0.0519903
PCBP2 poly(rC) binding protein 2 0.0437656
OGA O-GlcNAcase 0.0420773
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.041065
GOLGA4 golgin A4 0.0407373
PARD3 par-3 family cell polarity regulator 0.0400216
SMC4 structural maintenance of chromosomes 4 0.0399075
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0398842
MYOF myoferlin 0.0398113
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0395706
KMT2E lysine (K)-specific methyltransferase 2E 0.0395293
ZNF638 zinc finger protein 638 0.0389975
FRMD5 FERM domain containing 5 0.0385457
SPAG9 sperm associated antigen 9 0.0380291
RBM25 RNA binding motif protein 25 0.0374691
FMNL2 formin-like 2 0.0368679
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0365841
PTK2 protein tyrosine kinase 2 0.0365142
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0352266
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0347543
XPO1 exportin 1 0.0333464
GPHN gephyrin 0.0330784
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0326919
CTBP2 C-terminal binding protein 2 0.0318842
ATP11B ATPase, class VI, type 11B 0.0315724
FAM3C family with sequence similarity 3, member C 0.0313811
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0308349
RIMKLB ribosomal modification protein rimK-like family member B 0.0307221
NAV2 neuron navigator 2 0.0306378
TOP1 topoisomerase (DNA) I 0.030531
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0298255
DLG1 discs, large homolog 1 (Drosophila) 0.0297075
CCNL1 cyclin L1 0.029109
ARHGAP26 Rho GTPase activating protein 26 0.0286965
CCNY cyclin Y 0.0285167
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0284249
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0283246
DTNA dystrobrevin, alpha 0.0281137
ESYT2 extended synaptotagmin-like protein 2 0.0279793
SETD5 SET domain containing 5 0.0278772
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0274988
RYBP RING1 and YY1 binding protein 0.0274448
ECT2 epithelial cell transforming 2 0.0272724
AKAP9 A kinase (PRKA) anchor protein 9 0.0267554
EHBP1 EH domain binding protein 1 0.0266406
IRS2 insulin receptor substrate 2 0.0265474
TRA2A transformer 2 alpha homolog (Drosophila) 0.0264913
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.02632
PCLO piccolo presynaptic cytomatrix protein 0.0260533
SPIDR scaffolding protein involved in DNA repair 0.0259406
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0257068
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0256202
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0256129
RUNX1 runt-related transcription factor 1 0.0254962
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0254421
EZR ezrin 0.0254097
SENP6 SUMO1/sentrin specific peptidase 6 0.0253841
ANKRD28 ankyrin repeat domain 28 0.0252181
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.025208
KLF12 Kruppel-like factor 12 0.0247186
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0247171
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0246661
NCEH1 neutral cholesterol ester hydrolase 1 0.0245765
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0244712
FAF1 Fas (TNFRSF6) associated factor 1 0.0242023
SMAD3 SMAD family member 3 0.0239302
BCAR3 breast cancer anti-estrogen resistance 3 0.0239034
CANX calnexin 0.0237406
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0236724
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0234813
PDIA3 protein disulfide isomerase family A, member 3 0.0234586
FLNB filamin B, beta 0.0234547
NRIP1 nuclear receptor interacting protein 1 0.0234046
NAP1L1 nucleosome assembly protein 1-like 1 0.0233504
RIOK3 RIO kinase 3 0.022992
TRA2B transformer 2 beta homolog (Drosophila) 0.0228892
RBM39 RNA binding motif protein 39 0.0228575
NAMPT nicotinamide phosphoribosyltransferase 0.0228263
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0227878
RASA2 RAS p21 protein activator 2 0.0227866
CHD1 chromodomain helicase DNA binding protein 1 0.0227764
WSB1 WD repeat and SOCS box containing 1 0.0227504
UBA6 ubiquitin-like modifier activating enzyme 6 0.0226117
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0225684
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.0224661
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0224386
KMT2C lysine (K)-specific methyltransferase 2C 0.0224106
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0223415
ZFAND3 zinc finger, AN1-type domain 3 0.022285
ZMYM2 zinc finger, MYM-type 2 0.0222031
COG5 component of oligomeric golgi complex 5 0.0220945
BIRC6 baculoviral IAP repeat containing 6 0.0220889
SHB Src homology 2 domain containing adaptor protein B 0.0220685

decreased expression

Symbol Name Standardized Value
MUC4 mucin 4, cell surface associated -0.125612
TPT1 tumor protein, translationally-controlled 1 -0.116268
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.115813
TMSB10 thymosin beta 10 -0.110464
LMO7 LIM domain 7 -0.109488
TMSB4X thymosin beta 4, X-linked -0.107491
F3 coagulation factor III (thromboplastin, tissue factor) -0.103567
SOX4 SRY (sex determining region Y)-box 4 -0.100295
FN1 fibronectin 1 -0.0829438
DSG2 desmoglein 2 -0.0787046
MUC16 mucin 16, cell surface associated -0.0741269
TPM4 tropomyosin 4 -0.0735378
LAMC2 laminin, gamma 2 -0.0727173
ACTG1 actin gamma 1 -0.0688143
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.0667182
LAMB3 laminin, beta 3 -0.0633171
PLSCR1 phospholipid scramblase 1 -0.0619908
IGFBP3 insulin-like growth factor binding protein 3 -0.0605427
PLAU plasminogen activator, urokinase -0.0601264
PLAUR plasminogen activator, urokinase receptor -0.0525317
CLDN1 claudin 1 -0.0521152
FTH1 ferritin, heavy polypeptide 1 -0.0512665
CD59 CD59 molecule, complement regulatory protein -0.0496466
MACC1 metastasis associated in colon cancer 1 -0.049261
OSMR oncostatin M receptor -0.0489747
KRT17 keratin 17, type I -0.0487376
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0483795
RAP2B RAP2B, member of RAS oncogene family -0.0482298
SYT14 synaptotagmin XIV -0.0477674
MYO1E myosin IE -0.0472845
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0457722
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.044679
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0440873
LIPH lipase, member H -0.043365
SVIL supervillin -0.043284
RPS19 ribosomal protein S19 -0.042897
ZBTB20 zinc finger and BTB domain containing 20 -0.042759
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0425877
RPL12 ribosomal protein L12 -0.0423996
AKAP12 A kinase (PRKA) anchor protein 12 -0.0413335
AHNAK AHNAK nucleoprotein -0.0412703
HDAC9 histone deacetylase 9 -0.0412064
ITGB8 integrin, beta 8 -0.0404491
S100A6 S100 calcium binding protein A6 -0.0403196
HLA-E major histocompatibility complex, class I, E -0.0400006
KLF6 Kruppel-like factor 6 -0.0395222
KLF5 Kruppel-like factor 5 (intestinal) -0.0390441
INHBA inhibin, beta A -0.0388172
KRT7 keratin 7, type II -0.0386969
RPL23 ribosomal protein L23 -0.0380184
KRT19 keratin 19, type I -0.0361144
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.036065
RPL34 ribosomal protein L34 -0.03582
VCL vinculin -0.0353593
UGCG UDP-glucose ceramide glucosyltransferase -0.033812
KRT18 keratin 18, type I -0.0337502
RNF213 ring finger protein 213 -0.0328516
HLA-B major histocompatibility complex, class I, B -0.0326421
RIGI RNA sensor RIG-I -0.0326101
CAPN2 calpain 2, (m/II) large subunit -0.0322289
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0322232
RPL8 ribosomal protein L8 -0.0322175
POTEF POTE ankyrin domain family, member F -0.0316971
DAPK1 death-associated protein kinase 1 -0.0316553
RPS6 ribosomal protein S6 -0.0311646
RPL30 ribosomal protein L30 -0.0310978
LOC112694756 uncharaterized LOC112694756 -0.0310481
RPL26 ribosomal protein L26 -0.0310394
IL1RAP interleukin 1 receptor accessory protein -0.0301872
RPL37 ribosomal protein L37 -0.0298064
ASS1 argininosuccinate synthase 1 -0.0297807
RACK1 receptor for activated C kinase 1 -0.0297576
G0S2 G0/G1 switch 2 -0.0297242
HLA-C major histocompatibility complex, class I, C -0.0295273
RPLP0 ribosomal protein, large, P0 -0.028637
RPS3 ribosomal protein S3 -0.028143
DSC3 desmocollin 3 -0.0280771
RPL18 ribosomal protein L18 -0.0276919
RPS12 ribosomal protein S12 -0.0274816
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.0272702
RPS15 ribosomal protein S15 -0.027132
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0270758
RPS24 ribosomal protein S24 -0.0268377
ETV6 ets variant 6 -0.0267517
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0263659
HMGA1 high mobility group AT-hook 1 -0.0263273
RPL31 ribosomal protein L31 -0.0262995
PDLIM5 PDZ and LIM domain 5 -0.0260434
TM4SF1 transmembrane 4 L six family member 1 -0.0260157
H1-0 H1.0 linker histone -0.0257969
C6ORF132 chromosome 6 open reading frame 132 -0.0252706
CFLAR CASP8 and FADD-like apoptosis regulator -0.0252344
CD2AP CD2-associated protein -0.0250797
ZDHHC13 zinc finger, DHHC-type containing 13 -0.0250449
STEAP4 STEAP family member 4 -0.0248891
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0246381
ARHGAP5 Rho GTPase activating protein 5 -0.0245225
RPS8 ribosomal protein S8 -0.0242428
LY6E lymphocyte antigen 6 complex, locus E -0.0242153
LPP LIM domain containing preferred translocation partner in lipoma -0.0240065