| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0642866 |
| PKM | pyruvate kinase, muscle | 0.0640874 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0625576 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.061253 |
| POTEF | POTE ankyrin domain family, member F | 0.0600327 |
| ANXA2 | annexin A2 | 0.0572823 |
| ZNF292 | zinc finger protein 292 | 0.0546969 |
| NAV2 | neuron navigator 2 | 0.0496496 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0480454 |
| MSN | moesin | 0.0480165 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0458174 |
| TFG | TRK-fused gene | 0.0437185 |
| MYO1B | myosin IB | 0.0432976 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0422366 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0405645 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0386639 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0380574 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0377237 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0377015 |
| PGM3 | phosphoglucomutase 3 | 0.0372509 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0370079 |
| CCNL1 | cyclin L1 | 0.0360866 |
| SEPTIN2 | septin 2 | 0.0358702 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0355842 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0353244 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0347768 |
| THBS1 | thrombospondin 1 | 0.0344622 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0342745 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0341328 |
| MSR1 | macrophage scavenger receptor 1 | 0.0334844 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0333492 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0332733 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0330086 |
| ITGAV | integrin, alpha V | 0.032815 |
| SMAD3 | SMAD family member 3 | 0.0325796 |
| SPAG9 | sperm associated antigen 9 | 0.0322846 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0321257 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0319044 |
| CENPF | centromere protein F, 350/400kDa | 0.031687 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0314398 |
| CLIC4 | chloride intracellular channel 4 | 0.0312695 |
| NUP58 | nucleoporin 58 | 0.0311406 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0307616 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0305316 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.030445 |
| GOLGA4 | golgin A4 | 0.0303322 |
| UTRN | utrophin | 0.0297796 |
| RTN4 | reticulon 4 | 0.0297551 |
| KYNU | kynureninase | 0.0296399 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0293342 |
| COG5 | component of oligomeric golgi complex 5 | 0.0288425 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0288205 |
| RAB10 | RAB10, member RAS oncogene family | 0.0287829 |
| ZNF644 | zinc finger protein 644 | 0.0287718 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0285444 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0284533 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0283984 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0278528 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.027528 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0273985 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0270955 |
| CALU | calumenin | 0.0270882 |
| CORO1C | coronin, actin binding protein, 1C | 0.0268801 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0267441 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0266984 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0266758 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0264763 |
| DENND4A | DENN/MADD domain containing 4A | 0.0263306 |
| USP3 | ubiquitin specific peptidase 3 | 0.0263229 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0260966 |
| FBXO32 | F-box protein 32 | 0.0260528 |
| ATP13A3 | ATPase type 13A3 | 0.0259736 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0257435 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0255298 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0255086 |
| SEPTIN7 | septin 7 | 0.0253466 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.025236 |
| SETD5 | SET domain containing 5 | 0.025087 |
| SNX14 | sorting nexin 14 | 0.025073 |
| SVIL | supervillin | 0.0249902 |
| XPO1 | exportin 1 | 0.0249723 |
| ZNF207 | zinc finger protein 207 | 0.0249694 |
| ATM | ATM serine/threonine kinase | 0.0249417 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0248761 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0246739 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0246453 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0245493 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0244996 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244955 |
| VMP1 | vacuole membrane protein 1 | 0.0244432 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0243297 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0241263 |
| RBM5 | RNA binding motif protein 5 | 0.0241022 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239237 |
| TGM2 | transglutaminase 2 | 0.0236313 |
| CLINT1 | clathrin interactor 1 | 0.0234602 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0233245 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0232674 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0231527 |
| DIAPH3 | diaphanous-related formin 3 | 0.0229049 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.153662 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.152669 |
| CDH13 | cadherin 13 | -0.146679 |
| MT2A | metallothionein 2A | -0.130007 |
| B2M | beta-2-microglobulin | -0.128631 |
| HLA-B | major histocompatibility complex, class I, B | -0.116406 |
| VIM | vimentin | -0.103201 |
| TMSB10 | thymosin beta 10 | -0.0987327 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.09325 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0862812 |
| FTL | ferritin, light polypeptide | -0.0822055 |
| COL1A1 | collagen, type I, alpha 1 | -0.0796091 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0793357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0769938 |
| COL5A1 | collagen, type V, alpha 1 | -0.0744334 |
| STC1 | stanniocalcin 1 | -0.072066 |
| IL1B | interleukin 1, beta | -0.0693309 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0637342 |
| LOXL2 | lysyl oxidase-like 2 | -0.0584105 |
| RPL12 | ribosomal protein L12 | -0.0568964 |
| CADM1 | cell adhesion molecule 1 | -0.0551481 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0550348 |
| RPS19 | ribosomal protein S19 | -0.0548312 |
| FAM20C | family with sequence similarity 20, member C | -0.0520447 |
| HLA-A | major histocompatibility complex, class I, A | -0.0519748 |
| FRMD4A | FERM domain containing 4A | -0.0518661 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0499615 |
| RPS6 | ribosomal protein S6 | -0.0499032 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0493199 |
| RAI14 | retinoic acid induced 14 | -0.0470992 |
| SP100 | SP100 nuclear antigen | -0.0470975 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0460248 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0460117 |
| NAV1 | neuron navigator 1 | -0.045953 |
| HLA-C | major histocompatibility complex, class I, C | -0.0454798 |
| RPL37A | ribosomal protein L37a | -0.0453691 |
| TMEM178B | transmembrane protein 178B | -0.0448922 |
| FNIP1 | folliculin interacting protein 1 | -0.0444291 |
| RPL35A | ribosomal protein L35a | -0.0442815 |
| RPS17 | ribosomal protein S17 | -0.0439102 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0439083 |
| RPLP2 | ribosomal protein, large, P2 | -0.0423462 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0418227 |
| RPLP1 | ribosomal protein, large, P1 | -0.0406088 |
| INHBA | inhibin, beta A | -0.0405125 |
| POU2F2 | POU class 2 homeobox 2 | -0.0394401 |
| TNS3 | tensin 3 | -0.0391547 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0382335 |
| RPS8 | ribosomal protein S8 | -0.0374201 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0364771 |
| EXT1 | exostosin glycosyltransferase 1 | -0.036261 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0350534 |
| RPS16 | ribosomal protein S16 | -0.034847 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0339043 |
| GRB10 | growth factor receptor-bound protein 10 | -0.033685 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329117 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0323557 |
| RPL31 | ribosomal protein L31 | -0.0321273 |
| OXR1 | oxidation resistance 1 | -0.0320004 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0318855 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0315534 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0315461 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0310731 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.030979 |
| CLMP | CXADR-like membrane protein | -0.0306411 |
| PTMA | prothymosin, alpha | -0.0303128 |
| PCBP3 | poly(rC) binding protein 3 | -0.0303037 |
| RIGI | RNA sensor RIG-I | -0.0302216 |
| TNNC1 | troponin C type 1 (slow) | -0.029612 |
| RPL37 | ribosomal protein L37 | -0.029557 |
| RPL34 | ribosomal protein L34 | -0.029219 |
| FOXN3 | forkhead box N3 | -0.0290894 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0290697 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0286639 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.028549 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0285016 |
| RPL26 | ribosomal protein L26 | -0.028373 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0283408 |
| IER3 | immediate early response 3 | -0.0281314 |
| RACK1 | receptor for activated C kinase 1 | -0.0277902 |
| RPL9 | ribosomal protein L9 | -0.0277373 |
| RPS12 | ribosomal protein S12 | -0.0276506 |
| PRRX1 | paired related homeobox 1 | -0.0274585 |
| AGBL1 | ATP/GTP binding protein-like 1 | -0.0274372 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0271358 |
| NBEA | neurobeachin | -0.0269564 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.02695 |
| MMP12 | matrix metallopeptidase 12 | -0.026839 |
| FAM107B | family with sequence similarity 107, member B | -0.0268307 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0268191 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0265798 |
| XAF1 | XIAP associated factor 1 | -0.0264395 |
| DNER | delta/notch-like EGF repeat containing | -0.0263712 |
| PARD3 | par-3 family cell polarity regulator | -0.0263093 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0262615 |
| RPS3 | ribosomal protein S3 | -0.0262184 |
| RPS25 | ribosomal protein S25 | -0.0261889 |
| RPL23 | ribosomal protein L23 | -0.0260133 |
| DENND1A | DENN/MADD domain containing 1A | -0.0257974 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0257878 |
