| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vinblastine (sulfate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vinblastine (sulfate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.093198 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0797189 |
| FN1 | fibronectin 1 | 0.0777114 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0609149 |
| SMYD3 | SET and MYND domain containing 3 | 0.0428825 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0423621 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0418739 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.032113 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0315953 |
| DST | dystonin | 0.030971 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0262758 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0256355 |
| ANXA2 | annexin A2 | 0.0254395 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0251787 |
| TRIM33 | tripartite motif containing 33 | 0.025098 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0248269 |
| CDK6 | cyclin-dependent kinase 6 | 0.0247966 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241723 |
| PRELID2 | PRELI domain containing 2 | 0.024128 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0234864 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0225448 |
| HELZ | helicase with zinc finger | 0.0224229 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0220513 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0220151 |
| HHAT | hedgehog acyltransferase | 0.0219107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0213836 |
| QKI | QKI, KH domain containing, RNA binding | 0.0212658 |
| COG5 | component of oligomeric golgi complex 5 | 0.0211809 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0209635 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0208756 |
| OGA | O-GlcNAcase | 0.0205773 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0201958 |
| ATXN1 | ataxin 1 | 0.0197503 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0193514 |
| ANK2 | ankyrin 2, neuronal | 0.0193142 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0181408 |
| AUTS2 | autism susceptibility candidate 2 | 0.0179918 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0175835 |
| EVI5 | ecotropic viral integration site 5 | 0.0169621 |
| CORO1C | coronin, actin binding protein, 1C | 0.0166046 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0165351 |
| PTK2 | protein tyrosine kinase 2 | 0.0165349 |
| EFNA5 | ephrin-A5 | 0.0163698 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.016331 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0163303 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0163191 |
| CTBP2 | C-terminal binding protein 2 | 0.0163124 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0162363 |
| MATR3 | matrin 3 | 0.0161821 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.015933 |
| OXSR1 | oxidative stress responsive 1 | 0.0158773 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0157474 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0157243 |
| FMNL2 | formin-like 2 | 0.0156014 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0155721 |
| HDAC9 | histone deacetylase 9 | 0.0155352 |
| CD109 | CD109 molecule | 0.0155182 |
| DENND1A | DENN/MADD domain containing 1A | 0.0154237 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0153686 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0152894 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.014935 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0148389 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0147324 |
| MORF4L2 | mortality factor 4 like 2 | 0.0146945 |
| OLA1 | Obg-like ATPase 1 | 0.0146906 |
| NEGR1 | neuronal growth regulator 1 | 0.0146101 |
| TCF12 | transcription factor 12 | 0.0145278 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0144277 |
| RNF145 | ring finger protein 145 | 0.014424 |
| USP3 | ubiquitin specific peptidase 3 | 0.0143689 |
| NF1 | neurofibromin 1 | 0.0143112 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0142726 |
| TFG | TRK-fused gene | 0.0141744 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0141136 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0140816 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0140475 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0140296 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0140252 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0139723 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0139087 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0138677 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0138176 |
| FRMD5 | FERM domain containing 5 | 0.013799 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0137936 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0137848 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0137211 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0137211 |
| RAD51B | RAD51 paralog B | 0.0136433 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0136069 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.013475 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0133879 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0133806 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.013368 |
| RASAL2 | RAS protein activator like 2 | 0.0133198 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0132599 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0132291 |
| TUBB | tubulin, beta class I | 0.0132075 |
| USP24 | ubiquitin specific peptidase 24 | 0.0131502 |
| CANX | calnexin | 0.0131426 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0129664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | -0.142233 |
| NLGN1 | neuroligin 1 | -0.122784 |
| VIM | vimentin | -0.120174 |
| RPS3 | ribosomal protein S3 | -0.107167 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105004 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0835045 |
| LSAMP | limbic system-associated membrane protein | -0.0833435 |
| NRG3 | neuregulin 3 | -0.0807757 |
| SQSTM1 | sequestosome 1 | -0.077921 |
| MT2A | metallothionein 2A | -0.077319 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0644867 |
| RPS12 | ribosomal protein S12 | -0.0620369 |
| TMSB10 | thymosin beta 10 | -0.0527887 |
| FRMD4A | FERM domain containing 4A | -0.0467274 |
| RPS6 | ribosomal protein S6 | -0.0453001 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450633 |
| RPS13 | ribosomal protein S13 | -0.0425569 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0399623 |
| RPL37A | ribosomal protein L37a | -0.0379238 |
| RPLP2 | ribosomal protein, large, P2 | -0.0376194 |
| RPS8 | ribosomal protein S8 | -0.0370836 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0367144 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0362046 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0360894 |
| PGK1 | phosphoglycerate kinase 1 | -0.035915 |
| SFTPA2 | surfactant protein A2 | -0.0351959 |
| B2M | beta-2-microglobulin | -0.03511 |
| FTL | ferritin, light polypeptide | -0.0343757 |
| HLA-B | major histocompatibility complex, class I, B | -0.0333059 |
| RPL35A | ribosomal protein L35a | -0.0329629 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0325809 |
| PMEL | premelanosome protein | -0.0325126 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322907 |
| RPL9 | ribosomal protein L9 | -0.0317409 |
| RPS23 | ribosomal protein S23 | -0.0314991 |
| RPS27A | ribosomal protein S27a | -0.0312423 |
| RPL38 | ribosomal protein L38 | -0.0310131 |
| PKM | pyruvate kinase, muscle | -0.0304924 |
| CTSB | cathepsin B | -0.0296898 |
| RPL36A | ribosomal protein L36a | -0.0296487 |
| S100A9 | S100 calcium binding protein A9 | -0.0290521 |
| TENM1 | teneurin transmembrane protein 1 | -0.0289764 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0286927 |
| RPS19 | ribosomal protein S19 | -0.0285629 |
| RPL31 | ribosomal protein L31 | -0.0284146 |
| RPL37 | ribosomal protein L37 | -0.028326 |
| RPL19 | ribosomal protein L19 | -0.0282759 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0281716 |
| TPI1 | triosephosphate isomerase 1 | -0.0278169 |
| RPS17 | ribosomal protein S17 | -0.0268721 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0268212 |
| POTEF | POTE ankyrin domain family, member F | -0.026758 |
| RPL32 | ribosomal protein L32 | -0.0259121 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.025884 |
| RPS2 | ribosomal protein S2 | -0.0253663 |
| PTMA | prothymosin, alpha | -0.0251703 |
| RPS24 | ribosomal protein S24 | -0.0250363 |
| RACK1 | receptor for activated C kinase 1 | -0.0250146 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0244856 |
| RPS29 | ribosomal protein S29 | -0.0244223 |
| RPS14 | ribosomal protein S14 | -0.0238403 |
| RPS16 | ribosomal protein S16 | -0.0232605 |
| RPL36 | ribosomal protein L36 | -0.022959 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0229003 |
| RPL11 | ribosomal protein L11 | -0.022823 |
| CLTC | clathrin, heavy chain (Hc) | -0.0224996 |
| ENO1 | enolase 1, (alpha) | -0.022369 |
| RPL12 | ribosomal protein L12 | -0.021937 |
| RPS21 | ribosomal protein S21 | -0.0218419 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0216072 |
| GOLGA4 | golgin A4 | -0.021433 |
| LDHA | lactate dehydrogenase A | -0.0214014 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.021285 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0212621 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.021235 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0211534 |
| APOD | apolipoprotein D | -0.0210357 |
| ANGPTL4 | angiopoietin-like 4 | -0.0205064 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0204764 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0201885 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0193618 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0193438 |
| ADAR | adenosine deaminase, RNA-specific | -0.019327 |
| RPL34 | ribosomal protein L34 | -0.0193264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0192784 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0192742 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0188727 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | -0.0187487 |
| FHIT | fragile histidine triad | -0.0185965 |
| SET | SET nuclear proto-oncogene | -0.0185047 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0184467 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0184333 |
| RPL7 | ribosomal protein L7 | -0.018305 |
| RPL7A | ribosomal protein L7a | -0.0182977 |
| UBC | ubiquitin C | -0.0182504 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0178497 |
| RPL23 | ribosomal protein L23 | -0.017775 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0177147 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0176966 |
| LMNA | lamin A/C | -0.0175685 |
