| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vismodegib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vismodegib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.106148 |
| NAV1 | neuron navigator 1 | 0.0887662 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0828229 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.077891 |
| PODXL | podocalyxin-like | 0.0751959 |
| CDH13 | cadherin 13 | 0.0646443 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0642951 |
| COL5A1 | collagen, type V, alpha 1 | 0.0588515 |
| GLIS3 | GLIS family zinc finger 3 | 0.0583791 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0509591 |
| AHNAK | AHNAK nucleoprotein | 0.0473533 |
| EGFR | epidermal growth factor receptor | 0.0378826 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0364107 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0362069 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0341639 |
| RASAL2 | RAS protein activator like 2 | 0.0339481 |
| EFNA5 | ephrin-A5 | 0.033507 |
| FRMD4A | FERM domain containing 4A | 0.0330476 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0320157 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0315889 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0314309 |
| VEGFC | vascular endothelial growth factor C | 0.0303345 |
| SMYD3 | SET and MYND domain containing 3 | 0.03003 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0296404 |
| DST | dystonin | 0.0296263 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0282292 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278598 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.027299 |
| CDK13 | cyclin-dependent kinase 13 | 0.0270388 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0270152 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.02632 |
| AUTS2 | autism susceptibility candidate 2 | 0.0262255 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0260954 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0258537 |
| DCLK2 | doublecortin-like kinase 2 | 0.0255954 |
| VCL | vinculin | 0.0254941 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0251072 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0243968 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0241009 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0237814 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0235182 |
| NEK7 | NIMA-related kinase 7 | 0.0231958 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0231727 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0229701 |
| MYOF | myoferlin | 0.0228195 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0227996 |
| INTS6 | integrator complex subunit 6 | 0.0226631 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0225144 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0223285 |
| HDAC9 | histone deacetylase 9 | 0.0222534 |
| CYTH3 | cytohesin 3 | 0.0221333 |
| PLAT | plasminogen activator, tissue | 0.0220889 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0220182 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0216155 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0212965 |
| RAI14 | retinoic acid induced 14 | 0.0212143 |
| IPO9 | importin 9 | 0.0210669 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0208894 |
| GOLGB1 | golgin B1 | 0.0204618 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0196764 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.019659 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0196434 |
| PRSS23 | protease, serine, 23 | 0.0196219 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0192623 |
| RNF213 | ring finger protein 213 | 0.0192247 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0191234 |
| PRELID2 | PRELI domain containing 2 | 0.0189112 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0188526 |
| CUX1 | cut-like homeobox 1 | 0.0186273 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0185563 |
| FN1 | fibronectin 1 | 0.0183637 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0180572 |
| NLGN4Y | neuroligin 4, Y-linked | 0.0179795 |
| EHBP1 | EH domain binding protein 1 | 0.0177533 |
| JAZF1 | JAZF zinc finger 1 | 0.0177195 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0176171 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0175474 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0173209 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.017274 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0170944 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0170304 |
| CD44 | CD44 molecule (Indian blood group) | 0.0169714 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0169634 |
| NF1 | neurofibromin 1 | 0.0169163 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0168686 |
| RNF144A | ring finger protein 144A | 0.0165442 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0164615 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0164593 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0164282 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0163914 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0163567 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0163423 |
| FAM120B | family with sequence similarity 120B | 0.0162905 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0161993 |
| USP47 | ubiquitin specific peptidase 47 | 0.0161199 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0161108 |
| ZNF638 | zinc finger protein 638 | 0.0159291 |
| EXOC6B | exocyst complex component 6B | 0.015928 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0158344 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0155822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181068 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.153772 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.124099 |
| TMSB10 | thymosin beta 10 | -0.110634 |
| NDRG1 | N-myc downstream regulated 1 | -0.109181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108072 |
| MT2A | metallothionein 2A | -0.105808 |
| VIM | vimentin | -0.095536 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0760855 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0656092 |
| UBC | ubiquitin C | -0.063179 |
| PTMA | prothymosin, alpha | -0.0623653 |
| SQSTM1 | sequestosome 1 | -0.0619044 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0590753 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0542503 |
| POTEF | POTE ankyrin domain family, member F | -0.0530903 |
| B2M | beta-2-microglobulin | -0.0505915 |
| LDHA | lactate dehydrogenase A | -0.0474965 |
| TPM4 | tropomyosin 4 | -0.0451391 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0449248 |
| CSTB | cystatin B (stefin B) | -0.0443346 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0433499 |
| ADM | adrenomedullin | -0.0433323 |
| STC1 | stanniocalcin 1 | -0.042603 |
| TAGLN2 | transgelin 2 | -0.0413747 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.041356 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0409964 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0409873 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0404119 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0399173 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0399125 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.038963 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.038873 |
| PKM | pyruvate kinase, muscle | -0.0379582 |
| RTN4 | reticulon 4 | -0.0375679 |
| FLNB | filamin B, beta | -0.0374682 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0370463 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0370306 |
| S100A6 | S100 calcium binding protein A6 | -0.0366301 |
| S100A10 | S100 calcium binding protein A10 | -0.0355677 |
| FTL | ferritin, light polypeptide | -0.0338093 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0333135 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0323629 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0319157 |
| COL1A2 | collagen, type I, alpha 2 | -0.0317667 |
| PFN1 | profilin 1 | -0.0297469 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0292587 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0290168 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0289496 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0286138 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0285122 |
| VEGFA | vascular endothelial growth factor A | -0.0278273 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0275401 |
| FOSL1 | FOS-like antigen 1 | -0.0274991 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0273244 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0272086 |
| MT1X | metallothionein 1X | -0.0269684 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0268586 |
| ANXA2 | annexin A2 | -0.026781 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0267806 |
| RND3 | Rho family GTPase 3 | -0.0259178 |
| CANX | calnexin | -0.0258368 |
| MYADM | myeloid-associated differentiation marker | -0.0248134 |
| RPS6 | ribosomal protein S6 | -0.024651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0246145 |
| TMSB4X | thymosin beta 4, X-linked | -0.0243291 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0242454 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0242106 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0241821 |
| CD99 | CD99 molecule | -0.0241036 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.023867 |
| PGK1 | phosphoglycerate kinase 1 | -0.0231495 |
| RIOK3 | RIO kinase 3 | -0.0229495 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0225568 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0225022 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0223931 |
| GNAS | GNAS complex locus | -0.0220547 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0218123 |
| INSIG1 | insulin induced gene 1 | -0.0217978 |
| RNF24 | ring finger protein 24 | -0.021657 |
| FAM107B | family with sequence similarity 107, member B | -0.0216295 |
| SEPTIN7 | septin 7 | -0.0216167 |
| HELZ | helicase with zinc finger | -0.0216029 |
| ZNF292 | zinc finger protein 292 | -0.0214393 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0212757 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212644 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0212622 |
| CLU | clusterin | -0.020969 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0209115 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0208298 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.020722 |
| PCBP2 | poly(rC) binding protein 2 | -0.0206594 |
| BSG | basigin (Ok blood group) | -0.020636 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0206345 |
| SEC24A | SEC24 family member A | -0.0204351 |
| RAI1 | retinoic acid induced 1 | -0.0203986 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0203862 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0203049 |
| IRF1 | interferon regulatory factor 1 | -0.0202652 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0201106 |
