| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vismodegib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vismodegib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.105579 |
| AHNAK | AHNAK nucleoprotein | 0.0965627 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0749481 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0704389 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0652976 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0638372 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0634721 |
| SMAD3 | SMAD family member 3 | 0.060885 |
| CD44 | CD44 molecule (Indian blood group) | 0.0558478 |
| FOXO1 | forkhead box O1 | 0.055571 |
| LMO7 | LIM domain 7 | 0.0543092 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0540395 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0527106 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0525282 |
| NAV2 | neuron navigator 2 | 0.0520843 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0492913 |
| PRELID2 | PRELI domain containing 2 | 0.0488059 |
| PTK2 | protein tyrosine kinase 2 | 0.0471859 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0469538 |
| MYOF | myoferlin | 0.045259 |
| ASPH | aspartate beta-hydroxylase | 0.0442308 |
| OSMR | oncostatin M receptor | 0.0436022 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0424978 |
| CAPRIN2 | caprin family member 2 | 0.0423897 |
| PLEC | plectin | 0.0423302 |
| LAMC2 | laminin, gamma 2 | 0.0418762 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0406708 |
| RIN2 | Ras and Rab interactor 2 | 0.0402538 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0398845 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0388869 |
| KIAA1217 | KIAA1217 | 0.0370409 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0363482 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0362604 |
| RAI14 | retinoic acid induced 14 | 0.0359796 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.035564 |
| BCL2L1 | BCL2-like 1 | 0.0349438 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340769 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.033557 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0327823 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0323666 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.031514 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0313645 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0313471 |
| ANO6 | anoctamin 6 | 0.0309405 |
| VCL | vinculin | 0.0306818 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0304641 |
| SEPTIN9 | septin 9 | 0.0301024 |
| NEK7 | NIMA-related kinase 7 | 0.0299251 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0298234 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0295253 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0294413 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0290336 |
| AMOTL1 | angiomotin like 1 | 0.0289936 |
| FNIP1 | folliculin interacting protein 1 | 0.0289429 |
| PODXL | podocalyxin-like | 0.0286108 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0276983 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.027635 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0274522 |
| EXT1 | exostosin glycosyltransferase 1 | 0.027206 |
| RAB10 | RAB10, member RAS oncogene family | 0.0271442 |
| RAD51B | RAD51 paralog B | 0.0263414 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0262954 |
| SMYD3 | SET and MYND domain containing 3 | 0.026034 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260074 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0251221 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.024963 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0248891 |
| BLCAP | bladder cancer associated protein | 0.0248743 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0245093 |
| OGA | O-GlcNAcase | 0.0244767 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.024245 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0241263 |
| AOPEP | aminopeptidase O (putative) | 0.0238965 |
| NF1 | neurofibromin 1 | 0.0232467 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0229988 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0229381 |
| MYO9A | myosin IXA | 0.0227979 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0227889 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0227722 |
| SBF2 | SET binding factor 2 | 0.0227289 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0225579 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0225369 |
| CUL4B | cullin 4B | 0.0223626 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0223506 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0222639 |
| FRMD6 | FERM domain containing 6 | 0.0221553 |
| MEF2A | myocyte enhancer factor 2A | 0.0219774 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0218595 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0217806 |
| BARX2 | BARX homeobox 2 | 0.0214697 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0212805 |
| DST | dystonin | 0.0208638 |
| KIF16B | kinesin family member 16B | 0.0208288 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0207925 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0206741 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0206716 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0206364 |
| MSN | moesin | 0.0205794 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0205544 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.020524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.229011 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149032 |
| PTMA | prothymosin, alpha | -0.0970742 |
| TMSB10 | thymosin beta 10 | -0.0919869 |
| CLU | clusterin | -0.090813 |
| B2M | beta-2-microglobulin | -0.0818592 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0720736 |
| RPS8 | ribosomal protein S8 | -0.0705038 |
| RPS6 | ribosomal protein S6 | -0.0684852 |
| POTEF | POTE ankyrin domain family, member F | -0.0673498 |
| S100A10 | S100 calcium binding protein A10 | -0.0667111 |
| NDRG1 | N-myc downstream regulated 1 | -0.0622719 |
| LDHA | lactate dehydrogenase A | -0.0576276 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0551508 |
| RPS21 | ribosomal protein S21 | -0.0540789 |
| MT2A | metallothionein 2A | -0.0511332 |
| TMSB4X | thymosin beta 4, X-linked | -0.0499746 |
| ANXA1 | annexin A1 | -0.0480714 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0474693 |
| GNAS | GNAS complex locus | -0.0467958 |
| RPS13 | ribosomal protein S13 | -0.0450029 |
| FTL | ferritin, light polypeptide | -0.0447992 |
| KRT17 | keratin 17, type I | -0.0440437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437924 |
| RPS3 | ribosomal protein S3 | -0.0436817 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.042918 |
| SQLE | squalene epoxidase | -0.0428081 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0427508 |
| HLA-B | major histocompatibility complex, class I, B | -0.0427125 |
| RPLP2 | ribosomal protein, large, P2 | -0.0412875 |
| S100A9 | S100 calcium binding protein A9 | -0.040223 |
| RPS19 | ribosomal protein S19 | -0.0399367 |
| RPL12 | ribosomal protein L12 | -0.039799 |
| RPL8 | ribosomal protein L8 | -0.0395264 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0395153 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0394956 |
| DSTN | destrin (actin depolymerizing factor) | -0.0391832 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0386714 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0382443 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382393 |
| RPL11 | ribosomal protein L11 | -0.0378717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0361424 |
| LMNA | lamin A/C | -0.0360661 |
| STC1 | stanniocalcin 1 | -0.0355863 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.035486 |
| S100A2 | S100 calcium binding protein A2 | -0.0348665 |
| YBX1 | Y box binding protein 1 | -0.0348417 |
| S100A6 | S100 calcium binding protein A6 | -0.0344525 |
| RPS14 | ribosomal protein S14 | -0.0344481 |
| RPS25 | ribosomal protein S25 | -0.0342781 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0336135 |
| RACK1 | receptor for activated C kinase 1 | -0.0335712 |
| RPL35A | ribosomal protein L35a | -0.0335517 |
| RPL23 | ribosomal protein L23 | -0.0334902 |
| S100A11 | S100 calcium binding protein A11 | -0.0320861 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0310615 |
| ENO1 | enolase 1, (alpha) | -0.0308321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0305429 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0304868 |
| RPL26 | ribosomal protein L26 | -0.0302881 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0299168 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0295346 |
| RPL34 | ribosomal protein L34 | -0.0293751 |
| PFN1 | profilin 1 | -0.0292686 |
| RPS23 | ribosomal protein S23 | -0.0290312 |
| TAGLN2 | transgelin 2 | -0.028931 |
| CALR | calreticulin | -0.0288386 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0288093 |
| RPS27 | ribosomal protein S27 | -0.0286966 |
| RPL31 | ribosomal protein L31 | -0.0286566 |
| RPS24 | ribosomal protein S24 | -0.027981 |
| RPS12 | ribosomal protein S12 | -0.0279133 |
| RPL37A | ribosomal protein L37a | -0.0277731 |
| PKM | pyruvate kinase, muscle | -0.0274972 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0274368 |
| RPL37 | ribosomal protein L37 | -0.0272205 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0269037 |
| PGK1 | phosphoglycerate kinase 1 | -0.0267129 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0259708 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0258365 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0257697 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0253499 |
| RPL27A | ribosomal protein L27a | -0.0252633 |
| RPLP0 | ribosomal protein, large, P0 | -0.025097 |
| CSTB | cystatin B (stefin B) | -0.0248676 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0248598 |
| MT1X | metallothionein 1X | -0.0242154 |
| RPL36 | ribosomal protein L36 | -0.0241223 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0239998 |
| RPL30 | ribosomal protein L30 | -0.0239045 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0238507 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0237786 |
| RPL32 | ribosomal protein L32 | -0.0237744 |
| RPS27A | ribosomal protein S27a | -0.023606 |
| RPS20 | ribosomal protein S20 | -0.0234638 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0230622 |
| MORF4L2 | mortality factor 4 like 2 | -0.0230042 |
| HLA-E | major histocompatibility complex, class I, E | -0.022998 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022928 |
| IGF2 | insulin-like growth factor 2 | -0.0228681 |
