| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vismodegib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vismodegib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TAS2R14 | taste receptor, type 2, member 14 | 0.0250229 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0237372 |
| TMF1 | TATA element modulatory factor 1 | 0.0230035 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0227496 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.022576 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0218266 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0215599 |
| RIGI | RNA sensor RIG-I | 0.0212351 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0206222 |
| H1-4 | H1.4 linker histone, cluster member | 0.0199136 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0198079 |
| LAMB3 | laminin, beta 3 | 0.0196411 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0194332 |
| RPS2 | ribosomal protein S2 | 0.0188641 |
| VCL | vinculin | 0.0188559 |
| PHF3 | PHD finger protein 3 | 0.0186573 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0183492 |
| RBM25 | RNA binding motif protein 25 | 0.0182314 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0180904 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0180828 |
| METTL15 | methyltransferase like 15 | 0.0180519 |
| EREG | epiregulin | 0.0179313 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0177546 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.017672 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0176563 |
| CANX | calnexin | 0.0173511 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0171756 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0171431 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0169366 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0169104 |
| DYM | dymeclin | 0.0166913 |
| ONECUT3 | one cut homeobox 3 | 0.01544 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0154386 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0151031 |
| SDC4 | syndecan 4 | 0.0150951 |
| COG6 | component of oligomeric golgi complex 6 | 0.0149773 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0147574 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0147134 |
| LAMA4 | laminin, alpha 4 | 0.0146578 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.014503 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0144236 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0142213 |
| RPL6 | ribosomal protein L6 | 0.0141739 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0139975 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0139088 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0138899 |
| RPL3 | ribosomal protein L3 | 0.013523 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0134584 |
| MTAP | methylthioadenosine phosphorylase | 0.0134125 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.013394 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.013224 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0132115 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.013184 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0131123 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0130859 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0129891 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0128821 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0127463 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0126539 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.012629 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.012604 |
| GAN | gigaxonin | 0.0125531 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0125055 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0123614 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0123134 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0123085 |
| GOLGA2 | golgin A2 | 0.0122902 |
| MYOF | myoferlin | 0.0122632 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0121513 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0120501 |
| COMMD10 | COMM domain containing 10 | 0.0119397 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0119156 |
| PAPOLA | poly(A) polymerase alpha | 0.0118173 |
| PMM2 | phosphomannomutase 2 | 0.01179 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0117262 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0115903 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0115115 |
| RPL13A | ribosomal protein L13a | 0.0114678 |
| FDPS | farnesyl diphosphate synthase | 0.011387 |
| EP300 | E1A binding protein p300 | 0.0113708 |
| MAP4 | microtubule-associated protein 4 | 0.0113493 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.0113392 |
| EXOC6B | exocyst complex component 6B | 0.0113028 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0112952 |
| TMSB4X | thymosin beta 4, X-linked | 0.0112823 |
| COG7 | component of oligomeric golgi complex 7 | 0.0112075 |
| MMS22L | MMS22-like, DNA repair protein | 0.0110955 |
| TUT7 | terminal uridylyl transferase 7 | 0.0110904 |
| EXOC4 | exocyst complex component 4 | 0.0109941 |
| HEATR5A | HEAT repeat containing 5A | 0.0109933 |
| PGM3 | phosphoglucomutase 3 | 0.010992 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0109595 |
| PLCH1 | phospholipase C, eta 1 | 0.0109575 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0109519 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0108627 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0108229 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0108072 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0107655 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0107558 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0107149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251795 |
| NDRG1 | N-myc downstream regulated 1 | -0.191194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169959 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.152815 |
| PTMA | prothymosin, alpha | -0.136137 |
| TXNIP | thioredoxin interacting protein | -0.112732 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0967306 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0903703 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0892555 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0863609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0782753 |
| LDHA | lactate dehydrogenase A | -0.0780098 |
| FAT1 | FAT atypical cadherin 1 | -0.0776252 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0738116 |
| ITGA6 | integrin, alpha 6 | -0.0735905 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0731567 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0722258 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0708594 |
| EZR | ezrin | -0.0663571 |
| ANXA2 | annexin A2 | -0.0653967 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0621605 |
| FLNB | filamin B, beta | -0.0587216 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0586742 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0569185 |
| HMGA1 | high mobility group AT-hook 1 | -0.0565723 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.05567 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0554671 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0554148 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.052672 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0521267 |
| S100A6 | S100 calcium binding protein A6 | -0.0518891 |
| ZNF292 | zinc finger protein 292 | -0.050765 |
| SETD5 | SET domain containing 5 | -0.0487116 |
| FAM13A | family with sequence similarity 13, member A | -0.0486074 |
| POTEF | POTE ankyrin domain family, member F | -0.0482734 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0482233 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0480549 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0472149 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0455276 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0452229 |
| TMSB10 | thymosin beta 10 | -0.0450085 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0443725 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0441572 |
| RPL23 | ribosomal protein L23 | -0.0440757 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0436102 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0435602 |
| MUC17 | mucin 17, cell surface associated | -0.0428503 |
| RPS6 | ribosomal protein S6 | -0.042301 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0422436 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0421989 |
| KRT19 | keratin 19, type I | -0.0421804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0418503 |
| RPL35A | ribosomal protein L35a | -0.0410053 |
| TNS4 | tensin 4 | -0.0405524 |
| S100A10 | S100 calcium binding protein A10 | -0.040045 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.039992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0398262 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0394981 |
| PERP | PERP, TP53 apoptosis effector | -0.0391161 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0387391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0386293 |
| RREB1 | ras responsive element binding protein 1 | -0.0385303 |
| MED13 | mediator complex subunit 13 | -0.0384257 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0380873 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0379016 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0375817 |
| JMJD1C | jumonji domain containing 1C | -0.0375581 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0374324 |
| MED13L | mediator complex subunit 13-like | -0.0370936 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0369564 |
| TPM4 | tropomyosin 4 | -0.036636 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0362197 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0358314 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0355973 |
| PCBP2 | poly(rC) binding protein 2 | -0.0352517 |
| DSPP | dentin sialophosphoprotein | -0.0351272 |
| WAC | WW domain containing adaptor with coiled-coil | -0.035111 |
| EMP1 | epithelial membrane protein 1 | -0.0350589 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0350566 |
| ITGB4 | integrin, beta 4 | -0.0349988 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.034949 |
| RPLP0 | ribosomal protein, large, P0 | -0.0343698 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0338501 |
| PGK1 | phosphoglycerate kinase 1 | -0.0334532 |
| FOSL1 | FOS-like antigen 1 | -0.0333689 |
| KRT18 | keratin 18, type I | -0.0332185 |
| FNBP1L | formin binding protein 1-like | -0.0328002 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0323078 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0322966 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321447 |
| PARD3 | par-3 family cell polarity regulator | -0.0319371 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0317337 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0317219 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0314446 |
| WDR45B | WD repeat domain 45B | -0.0312917 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0311336 |
| CCNY | cyclin Y | -0.0310702 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0310531 |
| FHL2 | four and a half LIM domains 2 | -0.0303227 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0303024 |
