| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vismodegib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vismodegib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.16795 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0904878 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0776936 |
| FMNL2 | formin-like 2 | 0.0775444 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0742677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0710787 |
| AHNAK | AHNAK nucleoprotein | 0.0702398 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0632233 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0631154 |
| CAPRIN2 | caprin family member 2 | 0.0595474 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0589853 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0500739 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0478848 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.046063 |
| FNIP1 | folliculin interacting protein 1 | 0.045995 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0453611 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0451798 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0442746 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0421463 |
| CADM2 | cell adhesion molecule 2 | 0.0416001 |
| SMYD3 | SET and MYND domain containing 3 | 0.0408305 |
| TP63 | tumor protein p63 | 0.0403312 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0397309 |
| YEATS2 | YEATS domain containing 2 | 0.038747 |
| CD44 | CD44 molecule (Indian blood group) | 0.0386916 |
| PTK2 | protein tyrosine kinase 2 | 0.0381533 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.036353 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0354228 |
| OGA | O-GlcNAcase | 0.0352226 |
| APP | amyloid beta (A4) precursor protein | 0.0350769 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0347743 |
| TNS3 | tensin 3 | 0.0347483 |
| SPAG9 | sperm associated antigen 9 | 0.0341702 |
| PGK1 | phosphoglycerate kinase 1 | 0.033231 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0330968 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0330849 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0330066 |
| EXOC4 | exocyst complex component 4 | 0.0325983 |
| RAD51B | RAD51 paralog B | 0.0324127 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0323973 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.03232 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0322312 |
| CANX | calnexin | 0.0322135 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0317118 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.031677 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0316025 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0315676 |
| EHBP1 | EH domain binding protein 1 | 0.0313138 |
| PDE10A | phosphodiesterase 10A | 0.0312066 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0310498 |
| XPO1 | exportin 1 | 0.0308245 |
| TMSB4X | thymosin beta 4, X-linked | 0.0305761 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0301664 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298293 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0296173 |
| DENND1A | DENN/MADD domain containing 1A | 0.0295717 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0291904 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.028697 |
| JMJD1C | jumonji domain containing 1C | 0.0286925 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0281827 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0281725 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0279697 |
| EFNA5 | ephrin-A5 | 0.0278855 |
| USP34 | ubiquitin specific peptidase 34 | 0.0276139 |
| ZNF217 | zinc finger protein 217 | 0.0271295 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0270517 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0270144 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0267527 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0265771 |
| VCL | vinculin | 0.0265507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0263954 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0262178 |
| MYOF | myoferlin | 0.0262067 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.025926 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0258045 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0257319 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0255014 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0252496 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.025085 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0244056 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0239945 |
| CLTC | clathrin, heavy chain (Hc) | 0.0239457 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0236697 |
| DNER | delta/notch-like EGF repeat containing | 0.0235532 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0232889 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0232229 |
| LOXL2 | lysyl oxidase-like 2 | 0.0230264 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0228689 |
| DENND5A | DENN/MADD domain containing 5A | 0.0228576 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227792 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0227627 |
| PRELID2 | PRELI domain containing 2 | 0.0227217 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0224532 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0221847 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0220673 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0220292 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0218843 |
| RNF213 | ring finger protein 213 | 0.0218839 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0216625 |
| CUL3 | cullin 3 | 0.0215434 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.263097 |
| VIM | vimentin | -0.195904 |
| MT2A | metallothionein 2A | -0.131692 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.112397 |
| TMSB10 | thymosin beta 10 | -0.0784876 |
| POTEF | POTE ankyrin domain family, member F | -0.0732383 |
| FTL | ferritin, light polypeptide | -0.0614332 |
| HMGA1 | high mobility group AT-hook 1 | -0.0597232 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0545712 |
| EGR1 | early growth response 1 | -0.0527986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0518343 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0437405 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0400136 |
| RPL35A | ribosomal protein L35a | -0.0368563 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0347558 |
| MT1E | metallothionein 1E | -0.0339224 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.033736 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0326011 |
| MT1X | metallothionein 1X | -0.0311679 |
| ACTG1 | actin gamma 1 | -0.0297395 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0290569 |
| RPL23 | ribosomal protein L23 | -0.0280534 |
| RPS6 | ribosomal protein S6 | -0.0275328 |
| RPS8 | ribosomal protein S8 | -0.0272752 |
| RPS19 | ribosomal protein S19 | -0.0268884 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0264835 |
| FOSL1 | FOS-like antigen 1 | -0.026294 |
| RPL12 | ribosomal protein L12 | -0.0238705 |
| RPL28 | ribosomal protein L28 | -0.0238462 |
| PFN1 | profilin 1 | -0.0231112 |
| RPL8 | ribosomal protein L8 | -0.0230173 |
| AREG | amphiregulin | -0.0229842 |
| RPLP0 | ribosomal protein, large, P0 | -0.0227166 |
| PCBP2 | poly(rC) binding protein 2 | -0.0222426 |
| LOC112694756 | uncharaterized LOC112694756 | -0.021972 |
| RPS23 | ribosomal protein S23 | -0.0208293 |
| NDRG1 | N-myc downstream regulated 1 | -0.0197842 |
| S100A6 | S100 calcium binding protein A6 | -0.0194963 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0191898 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0191169 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0184425 |
| SRGN | serglycin | -0.0183393 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0182325 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0176637 |
| CBX3 | chromobox homolog 3 | -0.0174321 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0173525 |
| RPL5 | ribosomal protein L5 | -0.0172947 |
| MYADM | myeloid-associated differentiation marker | -0.0171291 |
| RPS2 | ribosomal protein S2 | -0.0171211 |
| PKM | pyruvate kinase, muscle | -0.016979 |
| RACK1 | receptor for activated C kinase 1 | -0.0166608 |
| ANGPTL4 | angiopoietin-like 4 | -0.0165908 |
| RPS14 | ribosomal protein S14 | -0.0165007 |
| S100A9 | S100 calcium binding protein A9 | -0.0164854 |
| RPS3 | ribosomal protein S3 | -0.015726 |
| RPL35 | ribosomal protein L35 | -0.0153449 |
| S100A10 | S100 calcium binding protein A10 | -0.0152509 |
| RPLP1 | ribosomal protein, large, P1 | -0.0151893 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0151797 |
| BSG | basigin (Ok blood group) | -0.0151779 |
| PTMA | prothymosin, alpha | -0.0151581 |
| RPS4X | ribosomal protein S4, X-linked | -0.0150798 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0150641 |
| SEC24A | SEC24 family member A | -0.0150545 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0149009 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0148861 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0147339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0146488 |
| RPL36 | ribosomal protein L36 | -0.0145499 |
| CALR | calreticulin | -0.0144761 |
| RPS15 | ribosomal protein S15 | -0.0144724 |
| TAPBP | TAP binding protein (tapasin) | -0.0143779 |
| TPI1 | triosephosphate isomerase 1 | -0.0142997 |
| RPS13 | ribosomal protein S13 | -0.0141416 |
| EREG | epiregulin | -0.0141221 |
| BRD2 | bromodomain containing 2 | -0.0140634 |
| RPL18 | ribosomal protein L18 | -0.0134167 |
| RPL7A | ribosomal protein L7a | -0.0134141 |
| RPL9 | ribosomal protein L9 | -0.0132725 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0129353 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0127821 |
| RPL19 | ribosomal protein L19 | -0.0127791 |
| RPS25 | ribosomal protein S25 | -0.0127186 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0126935 |
| RPL36A | ribosomal protein L36a | -0.0126703 |
| RPS5 | ribosomal protein S5 | -0.012661 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0126486 |
| TXNRD1 | thioredoxin reductase 1 | -0.0125686 |
| YBX1 | Y box binding protein 1 | -0.0125144 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0122873 |
| ASTN2 | astrotactin 2 | -0.0122741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0121335 |
| RPLP2 | ribosomal protein, large, P2 | -0.0120738 |
| ATF4 | activating transcription factor 4 | -0.0118136 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0113879 |
| RPL31 | ribosomal protein L31 | -0.0112512 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0112312 |
| RPS29 | ribosomal protein S29 | -0.0110987 |
| RPL34 | ribosomal protein L34 | -0.0110915 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0110737 |
