| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vismodegib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vismodegib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDGFC | platelet derived growth factor C | 0.0660637 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0625018 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0609785 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0602275 |
| RTN4 | reticulon 4 | 0.0594311 |
| ANK2 | ankyrin 2, neuronal | 0.0568595 |
| ZNF292 | zinc finger protein 292 | 0.0541379 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0455669 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0451188 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.044982 |
| YAP1 | Yes-associated protein 1 | 0.0439145 |
| ZNF644 | zinc finger protein 644 | 0.0429364 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0425012 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0424599 |
| PYGB | phosphorylase, glycogen; brain | 0.040083 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0393769 |
| NBAS | neuroblastoma amplified sequence | 0.0385276 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0371454 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.036433 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0359104 |
| VCL | vinculin | 0.0356561 |
| SMYD3 | SET and MYND domain containing 3 | 0.0355894 |
| ZNF608 | zinc finger protein 608 | 0.0348613 |
| VMP1 | vacuole membrane protein 1 | 0.0343273 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0341974 |
| RBM39 | RNA binding motif protein 39 | 0.0341345 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0335431 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0334998 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0328258 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0326548 |
| ECT2 | epithelial cell transforming 2 | 0.032504 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031136 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310968 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0309565 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0300654 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0299368 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0297731 |
| RBM33 | RNA binding motif protein 33 | 0.0297681 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0294634 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0288798 |
| FLNB | filamin B, beta | 0.0288694 |
| PRELID2 | PRELI domain containing 2 | 0.0284331 |
| SFPQ | splicing factor proline/glutamine-rich | 0.028022 |
| CDC73 | cell division cycle 73 | 0.0279234 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0278944 |
| TJP1 | tight junction protein 1 | 0.0277703 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0277034 |
| RPL4 | ribosomal protein L4 | 0.0274941 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0274624 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0273025 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0270083 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0269948 |
| RBM26 | RNA binding motif protein 26 | 0.0269766 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0269456 |
| JMJD1C | jumonji domain containing 1C | 0.0267436 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0262557 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0260046 |
| MEF2A | myocyte enhancer factor 2A | 0.0259853 |
| CASC3 | cancer susceptibility candidate 3 | 0.0256975 |
| NCOA3 | nuclear receptor coactivator 3 | 0.025583 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0254488 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0253787 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0250831 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0249952 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0248981 |
| NCKAP1 | NCK-associated protein 1 | 0.0248508 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0247939 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0245793 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0244295 |
| NKTR | natural killer cell triggering receptor | 0.0240861 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0240011 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0239824 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0238407 |
| NUP58 | nucleoporin 58 | 0.0236476 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0235295 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0235105 |
| ATOSA | atos homolog A | 0.0234025 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.022926 |
| SQSTM1 | sequestosome 1 | 0.0227805 |
| CCNY | cyclin Y | 0.0227164 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0225707 |
| ATP11A | ATPase, class VI, type 11A | 0.0224994 |
| SEC24D | SEC24 family member D | 0.0224764 |
| PGK1 | phosphoglycerate kinase 1 | 0.0221549 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0220046 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0218042 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0218038 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0217034 |
| RBM25 | RNA binding motif protein 25 | 0.0216927 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0216786 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0216506 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0214835 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0213144 |
| PTK2 | protein tyrosine kinase 2 | 0.0212958 |
| FOXJ3 | forkhead box J3 | 0.0212306 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0212118 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0212107 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0210655 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0210076 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0208457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198483 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.114186 |
| PTMA | prothymosin, alpha | -0.111967 |
| ACTG1 | actin gamma 1 | -0.0770743 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0764955 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0746247 |
| BMP10 | bone morphogenetic protein 10 | -0.0742046 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0705559 |
| PFN1 | profilin 1 | -0.0625812 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0608427 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0555922 |
| PKM | pyruvate kinase, muscle | -0.0540616 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0536211 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0526869 |
| S100A6 | S100 calcium binding protein A6 | -0.0487234 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.046259 |
| RPS8 | ribosomal protein S8 | -0.0455064 |
| RPS6 | ribosomal protein S6 | -0.0438287 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0434067 |
| RPL35A | ribosomal protein L35a | -0.0424538 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.042163 |
| POTEF | POTE ankyrin domain family, member F | -0.0390092 |
| RPLP1 | ribosomal protein, large, P1 | -0.0367851 |
| HMGA1 | high mobility group AT-hook 1 | -0.0365285 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0362851 |
| ENO1 | enolase 1, (alpha) | -0.0353828 |
| S100A4 | S100 calcium binding protein A4 | -0.0351175 |
| RPLP0 | ribosomal protein, large, P0 | -0.034736 |
| AHNAK | AHNAK nucleoprotein | -0.03234 |
| LDHA | lactate dehydrogenase A | -0.0318019 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0315582 |
| RPS21 | ribosomal protein S21 | -0.0310208 |
| TPM4 | tropomyosin 4 | -0.0309811 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0309312 |
| MKI67 | marker of proliferation Ki-67 | -0.0305042 |
| GLI3 | GLI family zinc finger 3 | -0.0302938 |
| FTL | ferritin, light polypeptide | -0.0300184 |
| RPL32 | ribosomal protein L32 | -0.0300067 |
| RPL36 | ribosomal protein L36 | -0.0294209 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0292393 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291694 |
| PDE7B | phosphodiesterase 7B | -0.0287435 |
| RPL23 | ribosomal protein L23 | -0.028687 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.028069 |
| RPL34 | ribosomal protein L34 | -0.0280128 |
| DUSP6 | dual specificity phosphatase 6 | -0.0278328 |
| S100A9 | S100 calcium binding protein A9 | -0.0276449 |
| FOXP1 | forkhead box P1 | -0.027171 |
| NAV2 | neuron navigator 2 | -0.0268022 |
| ANXA1 | annexin A1 | -0.0264545 |
| RPL8 | ribosomal protein L8 | -0.0260572 |
| CCND1 | cyclin D1 | -0.0259174 |
| RPS19 | ribosomal protein S19 | -0.0258718 |
| RPL19 | ribosomal protein L19 | -0.0258388 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0256734 |
| RPL12 | ribosomal protein L12 | -0.0255167 |
| RPS23 | ribosomal protein S23 | -0.0254792 |
| RACK1 | receptor for activated C kinase 1 | -0.0253736 |
| RPL27A | ribosomal protein L27a | -0.0251208 |
| TXNRD1 | thioredoxin reductase 1 | -0.0247265 |
| TMSB10 | thymosin beta 10 | -0.0246199 |
| RPS11 | ribosomal protein S11 | -0.0246066 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0239238 |
| RPS14 | ribosomal protein S14 | -0.0238231 |
| RPL7A | ribosomal protein L7a | -0.0237208 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0237168 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0224616 |
| RPLP2 | ribosomal protein, large, P2 | -0.0220261 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0215987 |
| MTDH | metadherin | -0.0215523 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0215498 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0204181 |
| CCNI | cyclin I | -0.0203346 |
| MT2A | metallothionein 2A | -0.0202634 |
| RPS4X | ribosomal protein S4, X-linked | -0.0200527 |
| BSG | basigin (Ok blood group) | -0.0199813 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0199426 |
| ASTN2 | astrotactin 2 | -0.0197198 |
| TPI1 | triosephosphate isomerase 1 | -0.0195003 |
| RRBP1 | ribosome binding protein 1 | -0.0193855 |
| SBF2 | SET binding factor 2 | -0.0192531 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0192099 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0191033 |
| RPS13 | ribosomal protein S13 | -0.0191015 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0190984 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.018929 |
| RPS27A | ribosomal protein S27a | -0.0188683 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0188229 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0187931 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0187346 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0182316 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0181978 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.018068 |
| RPL31 | ribosomal protein L31 | -0.0180666 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0180552 |
| RPL28 | ribosomal protein L28 | -0.0180231 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0179676 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0178793 |
| RPS5 | ribosomal protein S5 | -0.0177605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0176386 |
