| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0468479 |
| FBN1 | fibrillin 1 | 0.0467849 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0324777 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0317228 |
| DSCAM | Down syndrome cell adhesion molecule | 0.022112 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0218519 |
| GPC6 | glypican 6 | 0.0216316 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0211424 |
| COL3A1 | collagen, type III, alpha 1 | 0.020526 |
| THBS2 | thrombospondin 2 | 0.020458 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0195812 |
| OGA | O-GlcNAcase | 0.0189066 |
| SLC22A23 | solute carrier family 22, member 23 | 0.01866 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0179522 |
| ARRDC3 | arrestin domain containing 3 | 0.0177175 |
| SEPTIN9 | septin 9 | 0.0174105 |
| COL1A2 | collagen, type I, alpha 2 | 0.0171777 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0166323 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0165095 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0159519 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0157232 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0156646 |
| SBF2 | SET binding factor 2 | 0.0156143 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0152818 |
| STC1 | stanniocalcin 1 | 0.015166 |
| ATXN1 | ataxin 1 | 0.0147785 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0145896 |
| OPTN | optineurin | 0.0140348 |
| LOX | lysyl oxidase | 0.0135334 |
| CLU | clusterin | 0.0134808 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0134017 |
| ATP13A3 | ATPase type 13A3 | 0.0132721 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0130022 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0129446 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0129285 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0128247 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0127258 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0126984 |
| NAV2 | neuron navigator 2 | 0.0126346 |
| TMOD1 | tropomodulin 1 | 0.0125662 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0122805 |
| VEGFA | vascular endothelial growth factor A | 0.0122555 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0122538 |
| APP | amyloid beta (A4) precursor protein | 0.0119655 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0119506 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.011931 |
| COG5 | component of oligomeric golgi complex 5 | 0.0118032 |
| FLNB | filamin B, beta | 0.0117417 |
| TXNIP | thioredoxin interacting protein | 0.0115078 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0115056 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0114865 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0114643 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0114209 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0113888 |
| LOXL2 | lysyl oxidase-like 2 | 0.0112605 |
| ANKRD36 | ankyrin repeat domain 36 | 0.011117 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0106929 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0106827 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0106462 |
| ANK2 | ankyrin 2, neuronal | 0.0105543 |
| SDC4 | syndecan 4 | 0.0103684 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0102964 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0100734 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0100661 |
| ITSN2 | intersectin 2 | 0.00999703 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00997488 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00973713 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00970376 |
| NGLY1 | N-glycanase 1 | 0.00962372 |
| MYO9A | myosin IXA | 0.00961795 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.00954318 |
| SVIL | supervillin | 0.0094722 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00946093 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.00916284 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.00914516 |
| FNBP1L | formin binding protein 1-like | 0.00904459 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00903021 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0089982 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00898306 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00897849 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.00896927 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.00896354 |
| PHF3 | PHD finger protein 3 | 0.00895254 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00891105 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00889384 |
| KIAA1217 | KIAA1217 | 0.0088907 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.00888238 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00886612 |
| GOLGA4 | golgin A4 | 0.00885603 |
| XPO1 | exportin 1 | 0.00884951 |
| TRIM22 | tripartite motif containing 22 | 0.00883372 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00868837 |
| AUTS2 | autism susceptibility candidate 2 | 0.00861235 |
| ARFGEF3 | ARFGEF family member 3 | 0.00856065 |
| LRRC49 | leucine rich repeat containing 49 | 0.00855399 |
| YEATS2 | YEATS domain containing 2 | 0.00851357 |
| SLC35F5 | solute carrier family 35, member F5 | 0.00844022 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00841636 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00829947 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00824376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.290764 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.276969 |
| TMSB10 | thymosin beta 10 | -0.217986 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.14141 |
| PODXL | podocalyxin-like | -0.120778 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.115705 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112196 |
| MAP1B | microtubule-associated protein 1B | -0.105928 |
| FN1 | fibronectin 1 | -0.0974809 |
| S100A10 | S100 calcium binding protein A10 | -0.0857907 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0853932 |
| CDH13 | cadherin 13 | -0.0852447 |
| PLAT | plasminogen activator, tissue | -0.0806816 |
| POTEF | POTE ankyrin domain family, member F | -0.079593 |
| SUCNR1 | succinate receptor 1 | -0.0744902 |
| S100A6 | S100 calcium binding protein A6 | -0.0736587 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0722441 |
| CSTB | cystatin B (stefin B) | -0.0661387 |
| LMNA | lamin A/C | -0.065159 |
| MT2A | metallothionein 2A | -0.0626822 |
| COL5A1 | collagen, type V, alpha 1 | -0.0620264 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0617405 |
| TAGLN2 | transgelin 2 | -0.0588164 |
| NAV1 | neuron navigator 1 | -0.0541854 |
| PRSS23 | protease, serine, 23 | -0.0536472 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0535482 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0521532 |
| SLC39A11 | solute carrier family 39, member 11 | -0.049835 |
| B2M | beta-2-microglobulin | -0.0490802 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0488405 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0439801 |
| TPM4 | tropomyosin 4 | -0.0431576 |
| PKM | pyruvate kinase, muscle | -0.0403956 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0401602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0396653 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0395782 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0392045 |
| HLA-B | major histocompatibility complex, class I, B | -0.0388414 |
| MX2 | MX dynamin-like GTPase 2 | -0.0383613 |
| CALR | calreticulin | -0.0374533 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0364747 |
| PTMA | prothymosin, alpha | -0.0364612 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0362586 |
| PFN1 | profilin 1 | -0.0349615 |
| LRRC17 | leucine rich repeat containing 17 | -0.0345968 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0330539 |
| TUBB4B | tubulin, beta 4B class IVb | -0.033021 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.033006 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0329735 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0327534 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0324822 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0322676 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0318151 |
| ASPH | aspartate beta-hydroxylase | -0.0316436 |
| S100A11 | S100 calcium binding protein A11 | -0.0315733 |
| CD59 | CD59 molecule, complement regulatory protein | -0.031551 |
| SEPTIN7 | septin 7 | -0.0314379 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0308987 |
| S100A4 | S100 calcium binding protein A4 | -0.0308797 |
| DCLK2 | doublecortin-like kinase 2 | -0.0308483 |
| CYTH3 | cytohesin 3 | -0.0308098 |
| CD99 | CD99 molecule | -0.0303213 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.030313 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.029448 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0291913 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0291835 |
| KRT81 | keratin 81, type II | -0.0290462 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281059 |
| TPM1 | tropomyosin 1 (alpha) | -0.0276904 |
| CCND1 | cyclin D1 | -0.0273978 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0270131 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0269045 |
| ACTG1 | actin gamma 1 | -0.0268508 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0266801 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0257239 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0257223 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0251116 |
| LDHA | lactate dehydrogenase A | -0.0247508 |
| SEC61G | Sec61 gamma subunit | -0.0247107 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0245397 |
| NDRG1 | N-myc downstream regulated 1 | -0.024224 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0241722 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0239642 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0236823 |
| ENO1 | enolase 1, (alpha) | -0.0234658 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0234552 |
| IL7R | interleukin 7 receptor | -0.0234522 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0234209 |
| RIGI | RNA sensor RIG-I | -0.0232738 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0232701 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.023042 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.022878 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0228061 |
| MT1X | metallothionein 1X | -0.0227471 |
| PLXNA2 | plexin A2 | -0.0225573 |
| EGFR | epidermal growth factor receptor | -0.0222154 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0221347 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0219544 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0217747 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0216414 |
