| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0555606 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0524825 |
| VIM | vimentin | 0.0520494 |
| TXNRD1 | thioredoxin reductase 1 | 0.0465531 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0411251 |
| TPM3 | tropomyosin 3 | 0.0401338 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0400786 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0398063 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0378117 |
| RRM2 | ribonucleotide reductase M2 | 0.0370519 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0367836 |
| ASPH | aspartate beta-hydroxylase | 0.0341622 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0324873 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.0308241 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0300951 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0297813 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0295679 |
| WWOX | WW domain containing oxidoreductase | 0.028886 |
| BCHE | butyrylcholinesterase | 0.0287611 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0282653 |
| PRELID2 | PRELI domain containing 2 | 0.0273864 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0263273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0259447 |
| FOSL1 | FOS-like antigen 1 | 0.0258343 |
| EXOC6B | exocyst complex component 6B | 0.0255489 |
| NHSL1 | NHS-like 1 | 0.0250485 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0248766 |
| RTN4 | reticulon 4 | 0.0246335 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0244668 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0238282 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0237751 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0234148 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0230447 |
| XPO1 | exportin 1 | 0.0228072 |
| IPO7 | importin 7 | 0.0226329 |
| RPL27 | ribosomal protein L27 | 0.0226004 |
| RPS12 | ribosomal protein S12 | 0.0225285 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0224362 |
| CPOX | coproporphyrinogen oxidase | 0.0223692 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0222655 |
| RHOA | ras homolog family member A | 0.0219687 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0217229 |
| VMP1 | vacuole membrane protein 1 | 0.0215835 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.021301 |
| DSPP | dentin sialophosphoprotein | 0.0211344 |
| NUDC | nudC nuclear distribution protein | 0.0211101 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0210749 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0209118 |
| SPATA6 | spermatogenesis associated 6 | 0.0209023 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0208453 |
| SSR1 | signal sequence receptor, alpha | 0.0203566 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.020335 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0202225 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0202078 |
| FGF14 | fibroblast growth factor 14 | 0.020013 |
| PRKCE | protein kinase C, epsilon | 0.0199198 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0198506 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0198236 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.019734 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0191805 |
| RPL4 | ribosomal protein L4 | 0.0191657 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0191098 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0189482 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0187516 |
| RPS27 | ribosomal protein S27 | 0.018376 |
| SFTPA2 | surfactant protein A2 | 0.0182087 |
| SMYD3 | SET and MYND domain containing 3 | 0.0181844 |
| YAP1 | Yes-associated protein 1 | 0.0179205 |
| TMEM106B | transmembrane protein 106B | 0.0179151 |
| CSMD1 | CUB and Sushi multiple domains 1 | 0.0179039 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0178841 |
| ZFR | zinc finger RNA binding protein | 0.017868 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0178456 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0177892 |
| MAP7 | microtubule-associated protein 7 | 0.0176839 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0176714 |
| LCLAT1 | lysocardiolipin acyltransferase 1 | 0.0175828 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0175282 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0175229 |
| TPM4 | tropomyosin 4 | 0.0174879 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0172936 |
| PCM1 | pericentriolar material 1 | 0.0172884 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.017251 |
| AFDN | afadin, adherens junction formation factor | 0.0171003 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0169886 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0168964 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0168031 |
| MCL1 | myeloid cell leukemia 1 | 0.016683 |
| IL6ST | interleukin 6 signal transducer | 0.0166621 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0166392 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0164512 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0164469 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0164023 |
| STMN1 | stathmin 1 | 0.01633 |
| CLSPN | claspin | 0.0161775 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0161582 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0159377 |
| LMO7 | LIM domain 7 | 0.015931 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0159007 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.164185 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110943 |
| NLGN1 | neuroligin 1 | -0.0887997 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0832951 |
| DST | dystonin | -0.0754999 |
| MMP12 | matrix metallopeptidase 12 | -0.0733961 |
| AREG | amphiregulin | -0.0714141 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0712222 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0675618 |
| TMSB10 | thymosin beta 10 | -0.0599588 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0595754 |
| PCDH7 | protocadherin 7 | -0.057761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0564341 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.055804 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0556179 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0535397 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.05291 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0508501 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0503887 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0496835 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0488364 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0486201 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0477163 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0473942 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0470189 |
| EDN1 | endothelin 1 | -0.0469324 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0454469 |
| TENM3 | teneurin transmembrane protein 3 | -0.0453346 |
| SYT1 | synaptotagmin I | -0.0447548 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0444997 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0436765 |
| CCND1 | cyclin D1 | -0.0436637 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0431425 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0423875 |
| MYPN | myopalladin | -0.0420523 |
| ACTG1 | actin gamma 1 | -0.0420352 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0407094 |
| CCN2 | cellular communication network factor 2 | -0.0404281 |
| CDK6 | cyclin-dependent kinase 6 | -0.0398259 |
| SPAG9 | sperm associated antigen 9 | -0.0394995 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0394348 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0391457 |
| FTL | ferritin, light polypeptide | -0.0390606 |
| PEG10 | paternally expressed 10 | -0.0387494 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0380122 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0376055 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0372184 |
| PTMA | prothymosin, alpha | -0.0371876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.036345 |
| TBCA | tubulin folding cofactor A | -0.0363318 |
| ZNF804A | zinc finger protein 804A | -0.0357302 |
| KIF5B | kinesin family member 5B | -0.0356895 |
| ANXA1 | annexin A1 | -0.0356148 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0343321 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0341146 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0340567 |
| POTEF | POTE ankyrin domain family, member F | -0.0331804 |
| TSC22D2 | TSC22 domain family, member 2 | -0.03314 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0329048 |
| SRBD1 | S1 RNA binding domain 1 | -0.0325327 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0321078 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.031546 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.031467 |
| CCDC88A | coiled-coil domain containing 88A | -0.0314056 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0313785 |
| HSPB1 | heat shock 27kDa protein 1 | -0.031352 |
| PFN1 | profilin 1 | -0.0313457 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0312071 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0310896 |
| MKI67 | marker of proliferation Ki-67 | -0.0305566 |
| EPHA6 | EPH receptor A6 | -0.0304884 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0302978 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0302297 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0302041 |
| HMGA2 | high mobility group AT-hook 2 | -0.0300818 |
| USP34 | ubiquitin specific peptidase 34 | -0.0299335 |
| EDARADD | EDAR-associated death domain | -0.0297429 |
| RLF | rearranged L-myc fusion | -0.0292433 |
| TMEM131 | transmembrane protein 131 | -0.028887 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0287886 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0287052 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0283213 |
| NABP1 | nucleic acid binding protein 1 | -0.0281296 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.028127 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0279082 |
| FUS | FUS RNA binding protein | -0.027859 |
| PCBP2 | poly(rC) binding protein 2 | -0.0276916 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0275508 |
| ATG12 | autophagy related 12 | -0.0274939 |
| MPG | N-methylpurine-DNA glycosylase | -0.0270449 |
| TAOK1 | TAO kinase 1 | -0.0268571 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0268243 |
| POU2F1 | POU class 2 homeobox 1 | -0.0265329 |
| KLF6 | Kruppel-like factor 6 | -0.0264733 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0264193 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.026174 |
| FRYL | FRY-like | -0.0260995 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.026015 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0258713 |
| RPL26 | ribosomal protein L26 | -0.0258528 |
