| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.213302 |
| FRMD4A | FERM domain containing 4A | 0.115562 |
| VEGFA | vascular endothelial growth factor A | 0.0845244 |
| CA12 | carbonic anhydrase XII | 0.0775204 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0695183 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0686458 |
| RNF213 | ring finger protein 213 | 0.0651065 |
| GPC6 | glypican 6 | 0.0591052 |
| CP | ceruloplasmin (ferroxidase) | 0.0575476 |
| VIM | vimentin | 0.0533101 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0521994 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.049774 |
| TXNRD1 | thioredoxin reductase 1 | 0.0475689 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0460978 |
| GLIS3 | GLIS family zinc finger 3 | 0.0456936 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0436663 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0431422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0423259 |
| FTL | ferritin, light polypeptide | 0.0418161 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0394099 |
| ASPH | aspartate beta-hydroxylase | 0.0380791 |
| LDHA | lactate dehydrogenase A | 0.0378602 |
| EHBP1 | EH domain binding protein 1 | 0.0355636 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0343889 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0341022 |
| PFN1 | profilin 1 | 0.0330987 |
| HLA-B | major histocompatibility complex, class I, B | 0.033011 |
| PLIN2 | perilipin 2 | 0.0327676 |
| APOL1 | apolipoprotein L, 1 | 0.0316257 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0315964 |
| ITGAV | integrin, alpha V | 0.0312415 |
| FN1 | fibronectin 1 | 0.0306761 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0292382 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.02911 |
| SMYD3 | SET and MYND domain containing 3 | 0.029017 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0265734 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.025613 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0252321 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0246708 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0234065 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0232265 |
| PTH2R | parathyroid hormone 2 receptor | 0.0231548 |
| MX1 | MX dynamin-like GTPase 1 | 0.023059 |
| CALR | calreticulin | 0.0227876 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0222355 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0219819 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0219018 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0216269 |
| HLA-A | major histocompatibility complex, class I, A | 0.0216067 |
| FAT1 | FAT atypical cadherin 1 | 0.0216063 |
| TPM1 | tropomyosin 1 (alpha) | 0.0214001 |
| SP100 | SP100 nuclear antigen | 0.0212819 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0211152 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0211017 |
| NDRG1 | N-myc downstream regulated 1 | 0.0207165 |
| CD109 | CD109 molecule | 0.020471 |
| RPL35A | ribosomal protein L35a | 0.0203414 |
| RAD51B | RAD51 paralog B | 0.0199664 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0199582 |
| PTGR1 | prostaglandin reductase 1 | 0.0197616 |
| ANXA4 | annexin A4 | 0.0195703 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0194544 |
| LAMB3 | laminin, beta 3 | 0.0193462 |
| B2M | beta-2-microglobulin | 0.0193269 |
| TGM2 | transglutaminase 2 | 0.0192141 |
| EGR1 | early growth response 1 | 0.0191126 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0188342 |
| IFI44L | interferon-induced protein 44-like | 0.0187397 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0186778 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0184846 |
| FAM20C | family with sequence similarity 20, member C | 0.018448 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0180806 |
| TGFA | transforming growth factor, alpha | 0.0180029 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.0179986 |
| FAM120A | family with sequence similarity 120A | 0.0178454 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0176492 |
| BNC2 | basonuclin 2 | 0.0171762 |
| IL6 | interleukin 6 | 0.0171694 |
| SMIM14 | small integral membrane protein 14 | 0.0171637 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0170842 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0169833 |
| RIGI | RNA sensor RIG-I | 0.0168472 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0168282 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0167364 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0167003 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0165698 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.016541 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0164284 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0163224 |
| GDA | guanine deaminase | 0.0161844 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0159793 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0159692 |
| SCFD2 | sec1 family domain containing 2 | 0.0159072 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0158863 |
| OXR1 | oxidation resistance 1 | 0.0158723 |
| NUCB2 | nucleobindin 2 | 0.0157726 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.0154517 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0153515 |
| OSMR | oncostatin M receptor | 0.0152898 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0152458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.133197 |
| RPS2 | ribosomal protein S2 | -0.111743 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.101178 |
| RPS6 | ribosomal protein S6 | -0.0775084 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0763541 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0695452 |
| RBM39 | RNA binding motif protein 39 | -0.068474 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0682348 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0681798 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0656787 |
| CADM1 | cell adhesion molecule 1 | -0.0654971 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.064604 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0641077 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0630605 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0626292 |
| NOP58 | NOP58 ribonucleoprotein | -0.0610304 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0610252 |
| SPAG9 | sperm associated antigen 9 | -0.0606539 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601162 |
| JAK1 | Janus kinase 1 | -0.0598182 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0589378 |
| CLTC | clathrin, heavy chain (Hc) | -0.0550012 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0513647 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0509612 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0508408 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0501238 |
| WDR43 | WD repeat domain 43 | -0.0497148 |
| FMNL2 | formin-like 2 | -0.0497088 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0495769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0487553 |
| RPL7 | ribosomal protein L7 | -0.0458221 |
| RPL26 | ribosomal protein L26 | -0.045276 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0450349 |
| ANLN | anillin, actin binding protein | -0.0449184 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0441475 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0438516 |
| ATP13A3 | ATPase type 13A3 | -0.0438042 |
| ANKRD11 | ankyrin repeat domain 11 | -0.042842 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0428263 |
| UBQLN1 | ubiquilin 1 | -0.0417125 |
| SMAD3 | SMAD family member 3 | -0.0410222 |
| SET | SET nuclear proto-oncogene | -0.0401231 |
| TFG | TRK-fused gene | -0.0400037 |
| RHEB | Ras homolog enriched in brain | -0.0393732 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0393051 |
| MSN | moesin | -0.0391179 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0389515 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0388837 |
| DENND4A | DENN/MADD domain containing 4A | -0.0388126 |
| SUCO | SUN domain containing ossification factor | -0.0387663 |
| PTMA | prothymosin, alpha | -0.0384503 |
| GOLT1B | golgi transport 1B | -0.0383974 |
| RPS8 | ribosomal protein S8 | -0.0383131 |
| RPL19 | ribosomal protein L19 | -0.0379707 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0375375 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0368172 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0365124 |
| CLINT1 | clathrin interactor 1 | -0.0364766 |
| CRY1 | cryptochrome circadian clock 1 | -0.0364465 |
| PTK2 | protein tyrosine kinase 2 | -0.036193 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0356654 |
| SQSTM1 | sequestosome 1 | -0.0355443 |
| NUP98 | nucleoporin 98kDa | -0.0353649 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.035011 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0343277 |
| RASA2 | RAS p21 protein activator 2 | -0.0342945 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.034199 |
| IL6ST | interleukin 6 signal transducer | -0.0340685 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0338715 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0337888 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0334651 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0334456 |
| CD44 | CD44 molecule (Indian blood group) | -0.0333963 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0330181 |
| RTN4 | reticulon 4 | -0.0330148 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0329714 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0327928 |
| NAV2 | neuron navigator 2 | -0.032423 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0323334 |
| SBF2 | SET binding factor 2 | -0.0322689 |
| SDCBP | syndecan binding protein (syntenin) | -0.0322525 |
| QKI | QKI, KH domain containing, RNA binding | -0.0322465 |
| RPL38 | ribosomal protein L38 | -0.0322228 |
| RPL37A | ribosomal protein L37a | -0.0320944 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0320873 |
| DSTN | destrin (actin depolymerizing factor) | -0.0320451 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0317928 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0315776 |
| TLE4 | transducin-like enhancer of split 4 | -0.0314626 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0313613 |
| HIP1 | huntingtin interacting protein 1 | -0.0313434 |
| DENND2B | DENN domain containing 2B | -0.0313148 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0311757 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0311709 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.0309127 |
| MORF4L2 | mortality factor 4 like 2 | -0.0306804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0306487 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0303931 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0302853 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0302242 |
