| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vitamin K4 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vitamin K4_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.164159 |
| VEGFA | vascular endothelial growth factor A | 0.0852834 |
| ZNF292 | zinc finger protein 292 | 0.07492 |
| MED13L | mediator complex subunit 13-like | 0.054657 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0483401 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0462573 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0453135 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0385797 |
| TMSB4X | thymosin beta 4, X-linked | 0.0382241 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0375417 |
| QKI | QKI, KH domain containing, RNA binding | 0.0365791 |
| RNF145 | ring finger protein 145 | 0.0363079 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0354057 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0341142 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0308722 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0303715 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0303711 |
| OGA | O-GlcNAcase | 0.0296374 |
| RBM33 | RNA binding motif protein 33 | 0.0284106 |
| DBN1 | drebrin 1 | 0.0280697 |
| MEF2A | myocyte enhancer factor 2A | 0.027658 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0268278 |
| RBM25 | RNA binding motif protein 25 | 0.026582 |
| PTK2 | protein tyrosine kinase 2 | 0.0261187 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0261013 |
| PRELID2 | PRELI domain containing 2 | 0.0260584 |
| ZNF608 | zinc finger protein 608 | 0.0257237 |
| MTF2 | metal response element binding transcription factor 2 | 0.0255876 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0255458 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0250836 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0242873 |
| PNN | pinin, desmosome associated protein | 0.0240364 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0236873 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0236841 |
| ZNF148 | zinc finger protein 148 | 0.0235841 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0234565 |
| CDK8 | cyclin-dependent kinase 8 | 0.0233223 |
| ITGAV | integrin, alpha V | 0.0232352 |
| XPO1 | exportin 1 | 0.0231457 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0230085 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0229464 |
| KIF11 | kinesin family member 11 | 0.0225303 |
| DENND5A | DENN/MADD domain containing 5A | 0.0223292 |
| NEK7 | NIMA-related kinase 7 | 0.022294 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0222311 |
| NUP58 | nucleoporin 58 | 0.0221603 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0218753 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0218449 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0218288 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0218033 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0216328 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0215192 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0213802 |
| RBM5 | RNA binding motif protein 5 | 0.0213723 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.0211046 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0210515 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0209961 |
| UBP1 | upstream binding protein 1 (LBP-1a) | 0.0207774 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.020523 |
| TPM3 | tropomyosin 3 | 0.0204053 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.020327 |
| PCBP2 | poly(rC) binding protein 2 | 0.0203218 |
| CRY1 | cryptochrome circadian clock 1 | 0.019977 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0199344 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0195995 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0195402 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0194497 |
| STK4 | serine/threonine kinase 4 | 0.0193761 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.019305 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0192682 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0192367 |
| FAM133B | family with sequence similarity 133, member B | 0.0192347 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.019107 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0190561 |
| NRDC | nardilysin convertase | 0.0190374 |
| CENPF | centromere protein F, 350/400kDa | 0.018952 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0188931 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0186013 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0185639 |
| RFX7 | regulatory factor X, 7 | 0.018497 |
| MEMO1 | mediator of cell motility 1 | 0.0184927 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | 0.0184446 |
| PHIP | pleckstrin homology domain interacting protein | 0.0183613 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182803 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0182154 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0182069 |
| PHF3 | PHD finger protein 3 | 0.0181992 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0181015 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0180691 |
| FNBP1L | formin binding protein 1-like | 0.0180226 |
| PDGFC | platelet derived growth factor C | 0.018013 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0180033 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0179788 |
| ANO6 | anoctamin 6 | 0.0179765 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0178789 |
| PDZD8 | PDZ domain containing 8 | 0.0178725 |
| SIK3 | SIK family kinase 3 | 0.0178436 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0178362 |
| BCOR | BCL6 corepressor | 0.0177846 |
| ZNF654 | zinc finger protein 654 | 0.0177786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.163644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153594 |
| PTMA | prothymosin, alpha | -0.13202 |
| VIM | vimentin | -0.12998 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0815532 |
| ACTG1 | actin gamma 1 | -0.0780735 |
| HMGA2 | high mobility group AT-hook 2 | -0.074366 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0707813 |
| TMSB10 | thymosin beta 10 | -0.0641964 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0617513 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0583123 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0547116 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0545574 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0533557 |
| RPS23 | ribosomal protein S23 | -0.0513882 |
| RPS24 | ribosomal protein S24 | -0.0499596 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0458121 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0444574 |
| RPS8 | ribosomal protein S8 | -0.0429144 |
| FTL | ferritin, light polypeptide | -0.042284 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0414198 |
| RPL37A | ribosomal protein L37a | -0.0413905 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0410416 |
| RPL34 | ribosomal protein L34 | -0.041038 |
| RPL35A | ribosomal protein L35a | -0.0408818 |
| PGK1 | phosphoglycerate kinase 1 | -0.0400894 |
| NDRG1 | N-myc downstream regulated 1 | -0.0400561 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0370633 |
| FBXO11 | F-box protein 11 | -0.0366216 |
| RPLP2 | ribosomal protein, large, P2 | -0.0365758 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0362316 |
| MGP | matrix Gla protein | -0.0361455 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0358257 |
| RPL12 | ribosomal protein L12 | -0.0343553 |
| CANX | calnexin | -0.034098 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0336541 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0334825 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0330047 |
| PKM | pyruvate kinase, muscle | -0.0328991 |
| TUBB | tubulin, beta class I | -0.0319206 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0317148 |
| ENO1 | enolase 1, (alpha) | -0.0317095 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0313218 |
| RPS27A | ribosomal protein S27a | -0.0311684 |
| CDK6 | cyclin-dependent kinase 6 | -0.0305616 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0303033 |
| COL1A2 | collagen, type I, alpha 2 | -0.0299587 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0294499 |
| RPL36 | ribosomal protein L36 | -0.0293915 |
| RRBP1 | ribosome binding protein 1 | -0.0292715 |
| RPS29 | ribosomal protein S29 | -0.0292701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0290944 |
| EXOC4 | exocyst complex component 4 | -0.0279409 |
| ASPH | aspartate beta-hydroxylase | -0.0279284 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.027922 |
| KPNB1 | karyopherin (importin) beta 1 | -0.027846 |
| MT2A | metallothionein 2A | -0.0266618 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0266203 |
| CUX1 | cut-like homeobox 1 | -0.026448 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0263773 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0262807 |
| SEPTIN11 | septin 11 | -0.0262226 |
| HLA-B | major histocompatibility complex, class I, B | -0.0260381 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0259544 |
| IER3 | immediate early response 3 | -0.0258548 |
| RPL26 | ribosomal protein L26 | -0.0257821 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0257086 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0255945 |
| RPS13 | ribosomal protein S13 | -0.0255509 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0253703 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.025096 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0248624 |
| RPL38 | ribosomal protein L38 | -0.0247468 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0246349 |
| ATXN2 | ataxin 2 | -0.0244399 |
| MAP1B | microtubule-associated protein 1B | -0.0237979 |
| EFNA5 | ephrin-A5 | -0.0236503 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0234572 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0230851 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230017 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0229824 |
| RPL7 | ribosomal protein L7 | -0.0228727 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0228554 |
| LOC112694756 | uncharaterized LOC112694756 | -0.022305 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0222257 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0221388 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0220654 |
| CDH13 | cadherin 13 | -0.0219567 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0219027 |
| RPS16 | ribosomal protein S16 | -0.0218208 |
| CALU | calumenin | -0.0215768 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0214162 |
| RPL11 | ribosomal protein L11 | -0.0212756 |
| RPLP0 | ribosomal protein, large, P0 | -0.0211106 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0210248 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.020953 |
| RPL27A | ribosomal protein L27a | -0.0206659 |
| ANXA2 | annexin A2 | -0.020644 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0206314 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.020601 |
